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Investigating the Neandertal Origin of Dupuytren’s Disease

Recent research published by Oxford University Press in Molecular Biology and Evolution demonstrates that Dupuytren’s disease is partially Neandertal in origin.

15 Jun 2023

Understanding Potential Mechanisms Underlying Genetic Variation in Older Trees

Older, long-lived trees are thought to contribute more to the creation and maintenance of genetic mutations than short-lived trees, according to research on the link between the growth rate of tropical trees and the frequency of genetic mutations they collect.

7 Jun 2023

High-Resolution, Stable Brain Stimulation by Ultraflexible Nanoelectrodes

Conventional implantable medical devices designed for brain stimulation are often too rigid and bulky for what is one of the body's softest and most delicate tissues.

31 May 2023

Researchers Design Artificial Fibers that can Change Shape and Generate Force Like a Muscle

In two new studies, North Carolina State University researchers designed and tested a series of textile fibers that can change shape and generate force like a muscle.

26 May 2023

From Clocks to Cells: Unleashing the Potential of Dual Oscillatory Signaling

Christian Huygens recorded his observations of the synchronization of two pendulum clocks in 1665. It takes precise quantitative control to properly regulate oscillatory dynamics, which are seen in essential biological processes including circadian clocks, segmentation, and transcription factor responses in addition to physical systems.

22 May 2023

Untangling the Effects of Admixture on the Genomes of Modern Humans

The course of human history has been marked by complex patterns of migration, isolation, and admixture, the latter a term that refers to gene flow between individuals from different populations.

22 May 2023

Chemical Modification Improves Non-Viral Gene Editing as Well as a New Type of DNA Repair

Gene editing is a powerful method for both research and therapy. Since the advent of the Nobel Prize-winning CRISPR/Cas9 technology, a quick and accurate tool for genome editing discovered in 2012, scientists have been working to explore its capabilities and boost its performance.

12 May 2023

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene.

12 May 2023

New Insights on Cases of Post-Vaccine Heart Inflammation

Public health experts discovered an increase in cases of myocarditis, an inflammation of heart muscle, after the introduction of the new COVID-19 vaccinations two years ago, particularly in young males who had received mRNA vaccines.

8 May 2023

Tokyo Tech Researchers Discover How Surface Chemistry can Influence Adhesion of Bacterial Cells

The biofilm-forming bacteria E. coli adheres firmly to hydrophobic and hydrophilic protein-adsorbing self-assembling monolayers (SAMs) and weakly to hydrophilic protein-resisting SAMs, uncovered a recent study by Tokyo Tech researchers.

8 May 2023

Study Sheds Light on How Foxp2 Gene Controls the Ability to Produce Speech

Mutations of a gene called Foxp2 have been linked to a type of speech disorder called apraxia that makes it difficult to produce sequences of sound. A new study from MIT and National Yang Ming Chiao Tung University sheds light on how this gene controls the ability to produce speech.

5 May 2023

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Recent research from Temple University’s Lewis Katz School of Medicine and the University of Nebraska Medical Center demonstrates that gene-editing therapy aimed at two targets - HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that aids the virus getting into cells—can effectively eliminate HIV infection.

2 May 2023

Novel Mathematical Framework Evaluates the Dynamics of Adaptive Immune Evasion

Recent research published in the journal eLife proposes a theory for how cancer cells might actively adapt to the immune system to become resistant to immunotherapy.

27 Apr 2023

Next-Generation Sequencing Provides New Insights into Mutations of Mitochondrial DNA

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

17 Apr 2023

Microbial Drought Resistance Could Result in Soil Carbon Losses

Soil stores more carbon than plants and the atmosphere combined, and soil microbes are largely responsible for putting it there.

13 Apr 2023

Study helps understand at the cellular level how physical activity contributes to fitness during aging

Regular exercise can guarantee quality of life and longevity, specialists agree. However, exactly how exercise influences the functioning of muscle cells is poorly understood.

30 Mar 2023

Resistance genes in human gut influenced by national trends in antibiotic consumption

According to a new study performed at the Earlham Institute and Quadram Institute in Norwich, the community of microbes living in and on human bodies might be serving as a reservoir for antibiotic resistance.

28 Mar 2023

TurboID-based proximity labeling in meiotic cells of Arabidopsis thaliana

During meiosis, reshuffling of genetic information between homologous chromosomes through meiotic recombination creates variable gametes and hence genetic variation in offsprings.

14 Mar 2023

Analyzing the antimicrobial resistance profile of the main agent of urinary tract infections

The human intestine is an environment inhabited by many bacteria and other microorganisms collectively known as the gut microbiome, gut microbiota or intestinal flora. In most people, it contributes to wellness. A healthy gut indicates a stronger immune system, improved metabolism, and a healthy brain and heart, among other functions.