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Fusion Genes Emerge as Key Drivers in Cancer Development

Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic alterations result in the creation of hybrid genes with altered functions, often driving tumor progression.

25 Jun 2025

Newly Evolved Genes Found to Influence Human Cell Division

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria.

24 Jun 2025

CRNKL1 Gene Identified as Key to Rare Neurological Disorder

A study identifies specific changes in the CRNKL1 gene, revealing its crucial role in brain development and the severe impacts of related genetic disorders.

24 Jun 2025

Imported Seafood and the Spread of Colistin Resistance

Findings show imported seafood as a potential source of colistin-resistance genes, underscoring the urgency of addressing antimicrobial resistance globally.

23 Jun 2025

UT Southwestern Researchers Develop Multi-Organ Gene Editing Strategy

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows.

23 Jun 2025

Scientists Reveal Molecular Battle Between Maternal and Paternal Genes in Bees

Despite having identical genetic instructions, female honey bee larvae can develop into either long-lived reproductive queens or short-lived sterile workers who help rear their sisters rather than laying their own eggs.

23 Jun 2025

Anthrobots Reveal How Cells Can Build New Shapes Without Genetic Edits

Modern humans have existed for over 200,000 years, and each new generation has begun with a single cell-dividing, changing shape and function, organizing into tissues, organs, and limbs.

23 Jun 2025

Do Genetic Variants That Affect DNA Methylation Influence Colorectal Cancer Risk or Outcomes?

The study identifies genetic variants influencing colorectal cancer risk through DNA methylation, suggesting new avenues for targeted screening and prevention.

20 Jun 2025

Study Reveals TRF's Role in Reshaping Gut Microbiome and Metabolism

Metatranscriptomics uncovers how time-restricted feeding restores gut microbial cycles, offering insights into improving metabolic health and disease treatment.

20 Jun 2025

Organotypic Model of the Human Gut Epithelium Demonstrates Genetic Determinants of Shigella Colonization

A study in Nature Genetics uses organotypic gut models to reveal genome-wide genetic determinants of Shigella colonization, spotlighting type III secretion system effectors as crucial for early infection.

20 Jun 2025

UQ Tech Bringing Regenerative Medicines Closer Than Ever

Tiny gel droplets enhanced with University of Queensland technology could open new pathways to repairing and replacing damaged organs.

20 Jun 2025

Hundreds of Human Genes Found to Act Like On Off Switches

Gene expression, where cells use the genetic information encoded in DNA to produce proteins, has been thought of as a dimmer light.

19 Jun 2025

New Australian Chickpea Pan-Genome Poised to Boost National Chickpea Production

Researchers from the Centre for Crop and Food Innovation (CCFI) at Murdoch University have led the generation of a pan-genome tailored specifically to Australian chickpea varieties, paving the way for improved chickpea production across the country.

19 Jun 2025

Targeting RNA Polymerase 1 Rewires Cancer Cell Splicing and Halts Growth

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

19 Jun 2025

New STAMP Technique Combines Microscopy with Single-Cell RNA Analysis

Single-cell RNA sequencing provides scientists with important information about gene expression in health and disease.

18 Jun 2025

Quantifying Breast Cancer Heterogeneity Through Single-Cell Transcriptomics

Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental levels.

18 Jun 2025

Histone Variant H2AZ1 Identified as Key Driver of Stem Cell Aging

Cellular senescence-a state of irreversible growth arrest accompanied by chronic inflammation-is a major contributor to aging and tissue degeneration.

18 Jun 2025

Cas13d Gene Editing Shows Promise for Glaucoma Treatment

Gene editing with CRISPR shows promise in treating glaucoma by reducing intraocular pressure without permanent DNA changes, paving the way for future therapies.

18 Jun 2025

Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

17 Jun 2025

Ant Evolution Traced Through Genomic Reshuffling Across 100 Million Years

Aristotle praised the political organization of ant colonies while ancient Chinese Daoists appreciated ants as illustrative symbols showing how ephemeral human ambitions and power are.

17 Jun 2025