Embryo News and Research

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New technique controls gene activity without altering the DNA sequence of the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

7 Mar 2022

Researchers discover new stem cell population that closely matches existing human stem cells

Reik lab researchers’ recent discovery describes a new subpopulation of human embryonic stem cells that closely match the cells present at the genomic “wake up call” of the 8-cell embryo stage in humans.

28 Feb 2022

Researchers create a regulatory map of zebrafish genome

The zebrafish is an important model organism for studying things like genetic diseases. A regulatory map of its genome has been successfully created using high-throughput experiments and AI methods, a team led by Uwe Ohler now reports in Cell Genomics and Nature Machine Intelligence.

25 Feb 2022

Researchers gain better understanding of the fast signaling dynamics in stem cells

Divide, differentiate or die? Making decisions at the right time and place is what defines a cell's behavior and is particularly critical for stem cells of an developing organisms.

From The Max Planck Institute 25 Feb 2022

CRISPR/Cas9-mediated gene editing is now feasible in ticks

Researchers have successfully used CRISPR-Cas9 to edit the genomes of the black-legged tick. To accomplish this feat, they developed an embryo injection protocol that overcame a major barrier in the field.

17 Feb 2022

Researchers elucidate how early embryo cells begin to independently produce proteins

It happens in the first hours after fertilization: The cells of the early embryo begin to independently produce proteins, the building blocks for cells and organs.

16 Feb 2022

Moving cell groups push forward as they form organs, become cancerous and spread

Cells push and pull on surrounding tissue to move in groups as they form organs in an embryo, track down invading bacteria, and become cancerous and spread.

From New York University (NYU) 15 Feb 2022

Experts identify the master regulator of Nodal signaling in human embryonic stem cells

A new study has led to the discovery that the Hippo signaling effector YAP1 is a master controller of Nodal signaling in hESCs for a process crucial to human development.

14 Feb 2022

Epigenetic effects of pollutants can be transmitted over many generations in water fleas

A new study led by University of Liverpool reserchers has shown that the effects of pollutants can be transmitted over many generations in water fleas and may persist long enough to influence the evolutionary process.

10 Feb 2022

Study compares the chromosomal position of genes from diverse animals

Many of today's marine invertebrates, including sponges and jellyfish, have chromosomes with the same ancient structure they inherited from their primitive ancestors more than 600 million years ago, according to a new study.

9 Feb 2022

Scientists examine key mechanisms underlying genomic imprinting

Hereditary diseases, along with cancers and cardiovascular diseases, may be linked to genomic imprinting.

13 Jan 2022

Study finds gene family that regulates tissue-specific DNA methylation patterns

According to researchers at Salk, the CLASSY gene family controls which portions of the genome are turned off in a tissue-specific manner.

13 Jan 2022

New method to generate embryo-like cell complexes from the stem cells of mice

Researchers at the University of Bonn have developed a method to generate embryo-like cell complexes from the stem cells of mice. The method provides new insights into embryonic development. In the medium term, it might also be suitable for developing tests for substances that could be harmful to fertility. The study is published in the prestigious journal Nature Communications.

17 Dec 2021

Services to accelerate genome editing research

AMSBIO has expanded its range of custom gene editing services to complement its extensive portfolio of off-the-shelf CRISPR/Cas9 products.

From AMS Biotechnology 17 Dec 2021

Study identifies how embryonic cells detect stiffness in their environment

According to recent research by UCL scientists, cells in the developing embryo sense the stiffness of other cells surrounding them, a vital factor that makes them move together to form the skull and face.

From University College London 9 Dec 2021

Experts identify first non-coding RNA that controls chromosome loop formation

Recent research carried out by scientists from Massachusetts General Hospital (MGH) reveals that a significant player in the healthy development of female embryos also performs a vital role in controlling the behavior of chromosome loops and gene expression in both sexes.

7 Dec 2021

Researchers come up with a novel technique to produce single-sex litters

Researchers from the Francis Crick Institute along with the University of Kent utilized gene-editing technology to produce male-only and female-only mice litter with 100% efficacy.

7 Dec 2021

Glial cells in the heart play critical role in cardiac development and function

Glial cells in the heart help regulate heart rate and rhythm, and drive its development in the embryo, according to a new study publishing November 18th in the open-access journal PLOS Biology by Nina Kikel-Coury, Cody Smith and colleagues at the University of Notre Dame.

19 Nov 2021

Researchers identify new role of Hox genes in adulthood

Among their many extraordinary feats, some planarian flatworms reproduce by tearing off pieces of themselves to regenerate new worms.