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Researchers develop CAR-T cell therapy based on TCR signal transduction

The T cell receptor (TCR) is a key receptor that is responsible for detecting tumor antigens in T cells.

4 Aug 2020

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Diabetes, obesity and nonalcoholic fatty liver disease (NAFLD) are all common diseases that can lead to serious health implications.

3 Aug 2020

Study shows how psychological stress leads to debilitating vessel-clogging episodes

Researchers from the Albert Einstein College of Medicine have demonstrated that chronic psychological stress can result in painful vessel-clogging episodes—a frequent cause of hospitalizations and the most typical complication of sickle-cell disease or SCD.

31 Jul 2020

Rapid drug development yields potential treatment for yellow fever

Yellow fever, a hemorrhagic disease that is common in South America and sub-Saharan Africa, infects about 200,000 people per year and causes an estimated 30,000 deaths.

From Massachusetts Institute of Technology (MIT) 30 Jul 2020

Cholesterol-lowering medication improves function of the coronary arteries

In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart.

30 Jul 2020

Novel measurement technology may open up new potentials in personalized medicine

Similar to blood sugar, various biomarkers could in future be identified using just a few drops of blood. Researchers at Ruhr-Universität Bochum are developing a multi-analyte test strip for this purpose that will open up new potentials in personalized medicine by facilitating the continuous measurement of various parameters.

29 Jul 2020

A new cell-based gene therapy approach to correct hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

29 Jul 2020

Specific protein found at high levels in the blood of people with early signs of Alzheimer's

Two decades or more before symptoms arise, plaques of a sticky protein called amyloid begin forming in the brains of people later diagnosed with Alzheimer's disease.

29 Jul 2020

Supercomputer analyses point to a new pathway for COVID-19 inflammatory response

Analyses of lung fluid cells from COVID-19 patients conducted on a supercomputer point to patterns that may explain the body's response to SARS-CoV-2.

29 Jul 2020

Researchers uncover a novel mechanism by which cancer cells adapt to stress

Collaborative Cancer Research UK-funded studies from University of Oxford researchers have uncovered a new mechanism by which cancer cells adapt to the stresses they encounter as they grow and respond to therapies.

29 Jul 2020

Human genome may explain the neonatal origins of immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

29 Jul 2020

Novel label-free imaging method can differentiate between quiescent and activated T cells

T cells are the immune soldiers at the frontlines of the battle with infiltrating pathogens that seek to cause disease. A new study published in Nature Biomedical Engineering describes a novel label-free imaging technique that can differentiate active T cells from those off duty.

28 Jul 2020

Study shows the efficacy of plant-based diet on blood pressure

Consuming a plant-based diet can lower blood pressure even if small amounts of meat and dairy are consumed too, according to new research from the University of Warwick.

From The University of Warwick 27 Jul 2020

Heparin blocks SARS-CoV-2 infection in cell studies

In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease.

27 Jul 2020

New study shows how T cells function in atherosclerosis

High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the arteries. Statins have helped reduce mortality, but millions are still at risk.

27 Jul 2020

Higher levels of specific protein linked with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

27 Jul 2020

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

CAR-T cell therapy, which attacks cancer cells using a person's reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial led by researchers at UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston.

24 Jul 2020

Study shows KBTBD2 gene plays a key role in regulating insulin sensitivity

Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows.

24 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

Study shows the effectiveness of plant-based diets in controlling type 1 diabetes

Plant-based diets rich in whole carbohydrates can improve insulin sensitivity and other health markers in individuals with type 1 diabetes, according to two case studies published by researchers from the Physicians Committee for Responsible Medicine in the Journal of Diabetes & Metabolism.

24 Jul 2020

Blood News and Research

Researchers develop CAR-T cell therapy based on TCR signal transduction

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

Study shows how psychological stress leads to debilitating vessel-clogging episodes

Rapid drug development yields potential treatment for yellow fever

Cholesterol-lowering medication improves function of the coronary arteries

Novel measurement technology may open up new potentials in personalized medicine

A new cell-based gene therapy approach to correct hemophilia A

Specific protein found at high levels in the blood of people with early signs of Alzheimer's

Supercomputer analyses point to a new pathway for COVID-19 inflammatory response

Researchers uncover a novel mechanism by which cancer cells adapt to stress

Human genome may explain the neonatal origins of immune and inflammatory diseases

Novel label-free imaging method can differentiate between quiescent and activated T cells

Study shows the efficacy of plant-based diet on blood pressure

Heparin blocks SARS-CoV-2 infection in cell studies

New study shows how T cells function in atherosclerosis

Higher levels of specific protein linked with severity of COVID-19 symptoms

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

Study shows KBTBD2 gene plays a key role in regulating insulin sensitivity

New approach is more effective in treating certain blood cancers

Study shows the effectiveness of plant-based diets in controlling type 1 diabetes

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