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Nanobowl-stabilized liposomes are less leaky than regular liposomes

For many years, researchers have analyzed the use of liposomes, which are hollow spheres composed of lipid bilayers, to transmit chemotherapy drugs to tumor cells.

22 May 2020

Study shows senotherapy blunts the progression of liver tumors

According to a new study performed by researchers, “senotherapy” blunts the progression of liver tumor in animal models.

22 May 2020

Scientists develop novel model of liver cancer stem cells from normal iPSCs

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma.

22 May 2020

Genetic discoveries raise the promise of developing new treatments for schizophrenia

In recent years, genome-wide association studies have identified many different genetic variants associated with schizophrenia.

22 May 2020

Determining The Quantity And Location Of Lipids In The Brain

Researchers have developed a new technique that can determine the specific molecular form, location, and the number of lipids in samples of rat brain tissue.

22 May 2020

What If We Could Design Powerful Drugs Without Unwanted Side Effects?

Psychedelics have proven effective in treating depression and PTSD, but the medical use of these drugs is limited by their hallucinations.

22 May 2020

A 'Switch' That Turns Autoimmunity Drugs Into Powerful Anti-Cancer Treatments

Scientists have discovered a way to transform antibody drugs into antibodies with powerful anti-cancer activity through a simple molecular "switch".

22 May 2020

Cell-culture based in vitro test systems for screening of antitumor drugs

As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body.

21 May 2020

Bacteria’s drug resistance is not affected by genetic tradeoffs

Bacteria can still acquire antibiotic resistance even in the face of complex genetic compromises related to different concentrations of antibiotics.

21 May 2020

New technique can determine the location and quantity of lipids in the brain

A research team has devised a unique method that can establish the amount, location, and specific molecular form of lipids in rat brain tissue samples.

21 May 2020

Innovative tool to speed up the drug discovery process

A better understanding of the interaction between a molecule and the organism is important to consider its therapeutic potential.

21 May 2020

Novel technique can produce pure therapeutic drugs without side effects

Scientists from Hong Kong Baptist University have developed a novel technique that can produce pure therapeutic drugs without the associated side effects.

20 May 2020

Researchers uncover additional genetic cause for non-alcoholic fatty liver disease

In Germany about 18 million people suffer from non-alcoholic fatty liver. The causes of this disease are manifold and include environmental as well as genetic factors.

19 May 2020

Using light to control the viability and mobility of individual cells

Photopharmacology is the study that examines the use of light to change the impact of drugs on and off. For the first time, researchers from Jena, Munich, and New York have successfully applied this technique to regulate a component of cells that was earlier believed to be inaccessible.

18 May 2020

Aging neurons build up DNA damage, study finds

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Computational methods can help design protein-based vaccines

Vaccines are regarded as an effective intervention to stop the spread of infectious diseases. They produce antibodies by activating the immune system.

18 May 2020

Genes May Play A Role In Weight Gain From Birth Control

A woman's genetic make-up may cause her to gain weight when using a popular form of birth control, according to a study from researchers.

18 May 2020

Genome-wide pattern found in glioblastoma tumors predicts patient survival

For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma (GBM) -- the most common and the most aggressive brain cancer -- has simply been age at diagnosis.

15 May 2020

Study reveals nuanced role for oncogene in contact inhibition

Like subway com muters on a crowded train, cells generally prefer not to be packed in too tightly. In fact, they have set up mechanisms to avoid this, a phenomenon called "contact inhibition."

15 May 2020

Treating solid cancers using the formation of natural killer-tumor cell immunological synapse

There are immune cells in our bodies that directly destroy infected or cancer cells - they are called natural killer cells. Recently, a POSTECH research team has developed an integrative cancer therapy using adoptive natural killer cell therapy and chemotherapy.

14 May 2020