Biotherapeutics News and Research

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Scientists Uncover the Molecular Fingerprints of mRNA Vaccine-Induced T Cells

The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the Nobel-prize–winning technology is being adapted to fight cancer, with mRNA vaccines in clinical trials for melanoma, small cell lung cancer and bladder cancer, among others, opening the door to new ways of preventing and treating the disease.

17 Apr 2026

Early Epigenetic Changes and Gut Microbiome Interact to Shape Neurodevelopment

The gut microbiome and epigenetics-molecular switches that turn genes on or off-are intertwined, and both contribute to neurodevelopment, finds a study publishing April 10 in the Cell Press journal Cell Press Blue.

13 Apr 2026

Mosaic Cell Reprogramming Primes Skin for Rapid Injury Response

It is well known that students who prepare in advance perform better on exams. Now, it appears that the skin can do the same.

9 Apr 2026

Researchers Use Retron Systems to License DNA for Cellular Tasks

Stepping away from its billions-of-years-old role as a genetic "blueprint," DNA is now embarking on a new journey as an active "field agent" within cells. This research by a team led by Professor Jongmin Kim and Ph.D. candidate Geonhu Lee from the Department of Life Sciences at POSTECH (Pohang University of Science and Technology) was published in the online edition of the international chemistry journal, Nature Chemistry.

2 Apr 2026

Novel INSTALL Technology Achieves Non-Toxic Gene Integration in Multiple Cell Types

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

12 Mar 2026

Rentschler Biopharma and Coriolis Pharma Announce Strategic Collaboration for Integrated Biopharma Solutions

Rentschler Biopharma, a leading global contract development and manufacturing organization (CDMO) for biopharmaceuticals, and Coriolis Pharma, a globally operating contract research and development organization (CRDO) and a leader in formulation research and development for biopharmaceuticals, today announced a strategic collaboration.

2 Dec 2025

Study Shows Flatulence Gas Hydrogen is Crucial for Gut Health

Farts are causing a stink in the research world, but in a positive way.

24 Oct 2025

Gut Microbes Influence Human Genes and Health

The trillions of microbes that live in the human gut may play a bigger role in health than previously thought, according to a new research by the University of Hawaiʻi at Mānoa.

24 Sep 2025

USC Researchers Advance Toward Building Functional Synthetic Kidneys

A USC Stem Cell-led research team has achieved a major step forward in the effort to build mouse and human synthetic kidneys.

18 Sep 2025

Engineered Base Editor Corrects ACTA2 Mutation in Rare Childhood Disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

13 Sep 2025

Genome-Wide Study Connects Human Genetic Variation to Mycobiome Diversity and Disease

A new genome-wide study uncovers evidence of the first three-way relationships between human genetic variation, variation in the fungal component of the human microbiome - known as the mycobiome - and risk of developing chronic disease.

10 Sep 2025

Harbour BioMed and Insilico Collaborate on Advanced AI-Driven Antibody Discovery

Harbour BioMed (HKEX: 02142, the "Company"), a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on immunology and oncology, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced a strategic collaboration to accelerate the discovery and development of innovative therapeutic antibodies, leveraging their respective technological strengths in antibody discovery and artificial intelligence.

22 Feb 2025

Friendly Germs May Hold the Key to Overcoming Antimicrobial Resistance

Friendly germs armed with their own biological syringes and poisons could hold the key to overcoming the antimicrobial resistance crisis, according to a new study by biologists at the Universities of Manchester and Basel.

15 Jan 2025

New Treatment Targets Tumor Microenvironment to Fight Breast Cancer

"Build your enemy a golden bridge to retreat across" is a piece of advice offered by Sun Tzu in his ancient military treatise, The Art of War. It turns out that cancerous growths adopt this strategy in their battle against the immune system.

24 Dec 2024

Discovery of 18-Digit Code Unlocks Exosome-Based Drug Delivery

Researchers at The Ottawa Hospital and the University of Ottawa have discovered an 18-digit code that allows proteins to attach themselves to exosomes - tiny pinched-off pieces of cells that travel around the body and deliver biochemical signals.

12 Dec 2024

Mobile Genetic Elements Alter Antagonistic Strategies of Gut Bacteria

Bacteria evolve rapidly in the human gut by sharing genetic elements with each other. Bacteriodales is a prolific order of gut bacteria that trade hundreds of genetic elements.

25 Oct 2024

Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion.

16 Sep 2024

CRISPR and Antibodies Offer New Hope for Improving CAR-T Cell Therapy Outcomes

Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.

13 Sep 2024

Study Reveals How Damaged Cells Contribute to Chronic Kidney Disease Progression

A study published in Nature Communications provides new insight into how damaged cells interact within disease-promoting microenvironments following acute kidney injury, or AKI.

6 Sep 2024

The Impact of Catalysis for Site-Specific Protein Modification

As they recently reported in the journal Nature Chemistry, Boston College researchers have developed a new tool that can be used to develop novel biotherapeutics and protein-based research tools: the ability to precisely modify proteins using a mild charge of electricity.

6 Mar 2024