CRISPR News and Research

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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

Cysteine is one of the main building blocks that cells use to make proteins. But this amino acid is a double-edged sword–too much cysteine is toxic to the cell.

24 Sep 2026

A Tiny Worm Helps Scientists Unravel a Genetic Clue to Kidney Disease

A microscopic worm that has no kidneys is helping Rutgers scientists understand a genetic change suspected of causing a serious inherited kidney disease.

24 Sep 2026

Blocking Mitochondrial Iron Transport Protects Cells Against Elevated Cysteine Toxicity

Cysteine is one of the main building blocks that cells use to make proteins.

22 Sep 2026

Integrated DNA Technologies and Aldevron Launch New Cas9 mRNA Solutions to Accelerate Path From Gene Editing Research to Development

Danaher companies Integrated DNA Technologies (IDT), a global leader in genomics, and Aldevron, a premier manufacturing partner for DNA, RNA, and protein, today announced the launch of research grade S.p. Cas9 mRNA in wild type and SpyFi™ high-fidelity formats.

From Integrated DNA Technologies 18 Sep 2026

Single-Cell Multiomics Model Decodes Enhancer Networks in Rare Cell Populations

Understanding gene regulation may be the key to interpreting human disease genetics. Genes are regulated in part by stretches of DNA called enhancers, which define when, where, and how strongly each gene is turned on.

17 Sep 2026

Research Reveals Molecular Link Between Matrix Protein Motifs and Ameloblast Organization

Tooth enamel looks simple from the outside and consists of a hard, smooth surface built to withstand years of wear.

12 Sep 2026

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques can accurately edit genes in human embryos-giving scientists indispensable tools for understanding normal human development-but has also uncovered important risks that currently preclude the use of the techniques in the clinic.

10 Sep 2026

Human Embryos Repair Single-Strand DNA Damage Reliably but Fail at Double-Strand Breaks

Although DNA repair is one of the fundamental processes required for normal human embryonic development, little has been known about how it operates during the earliest stages of development.

10 Sep 2026

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one specialized for cytokine production and the other for direct killing.

7 Sep 2026

AI-Designed Protein Vehicle Enables Lower RNA Dosing While Maximizing Therapeutic Protein Expression

Researchers at Helmholtz Munich and TUM have developed Synthetic Transfer Vehicles (STVs), an entirely new class of RNA transporters. To do so, they combined naturally occurring protein building blocks with synthetic protein structures designed using generative AI.

3 Sep 2026

Bulky Molecular CRISPR Systems Barely Fit Inside Single Viral Vectors

The ability to precisely adjust the expression of genes inside the human body - ramping up protective ones and tamping down harmful ones - holds enormous potential for treating and preventing disease.

31 Aug 2026

Single-Gene Edits Fall Short of Stopping Immune Rejection in Beta Cell Grafts

In people with type 1 diabetes, the immune system mistakenly destroys the pancreatic beta cells responsible for producing insulin. Patients therefore require lifelong insulin therapy to regulate their blood glucose levels.

21 Aug 2026

Advanced AI Tools Sift Through Complex Data to Find Gene Mutations

One of the most important goals of studying genetics is to find genes that are involved with diseases. The problem is that most diseases aren't caused by a single gene or mutation.

19 Aug 2026

Method Reveals How Influenza A Takes Over Host Cell Machinery

A new study identifies influenza A virus interactions with human proteins, uncovering mechanisms of paraspeckle disruption and insights for antiviral development.

4 Aug 2026

New Base Editing Strategy Rewrites Genetic Code to Minimize Huntington's Symptoms

A gene editing tool designed to precisely rewrite the gene that causes Huntington's disease reduced toxic protein fragments and symptoms associated with the disease in mice, researchers at the University of Illinois Urbana-Champaign report.

30 Jul 2026

Type I CRISPR Systems Regulate Embedded Innate Immunity Genes in Neisseria

The main function of CRISPR-Cas systems, the revolutionary tool scientists now employ to edit genes, is to defend bacteria against threats such as viruses called bacteriophages. Researchers have continued to study all flavors of CRISPR-Cas systems (to date, 2 classes, 7 types and 46 subtypes have been identified) to understand all their capabilities.

27 Jul 2026

CRISPR Gene Editing Reveals How Enhancer Hierarchies Regulate Gene Expression

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated.

23 Jul 2026

Bacteria Use CRISPR-Cas to Control Diverse Innate Defense Systems

All cellular life-from humans to bacteria-possesses two layers of immunity: innate and adaptive. Scientists have long understood how these two types of immunity work together in higher organisms but not in the microbial world.

23 Jul 2026

UC San Diego and Innovative Genomics Institute Partner to Develop Cutting-Edge Genomic Tools

The University of California San Diego and the Innovative Genomics Institute (IGI), founded by Nobel laureate and CRISPR gene editing co-discoverer Jennifer Doudna, announced a new partnership today to jointly develop cutting-edge genomic tools for addressing large-scale challenges in health and the environment.

21 Jul 2026

CRISPR Technology Enables First Successful Gene Editing in Biting Midges

Scientists have successfully edited the genome of biting midges, opening the door to new research on how these insects transmit disease.

20 Jul 2026

CRISPR News and Research

Further Reading

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

A Tiny Worm Helps Scientists Unravel a Genetic Clue to Kidney Disease

Blocking Mitochondrial Iron Transport Protects Cells Against Elevated Cysteine Toxicity

Integrated DNA Technologies and Aldevron Launch New Cas9 mRNA Solutions to Accelerate Path From Gene Editing Research to Development

Single-Cell Multiomics Model Decodes Enhancer Networks in Rare Cell Populations

Research Reveals Molecular Link Between Matrix Protein Motifs and Ameloblast Organization

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

Human Embryos Repair Single-Strand DNA Damage Reliably but Fail at Double-Strand Breaks

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

AI-Designed Protein Vehicle Enables Lower RNA Dosing While Maximizing Therapeutic Protein Expression

Bulky Molecular CRISPR Systems Barely Fit Inside Single Viral Vectors

Single-Gene Edits Fall Short of Stopping Immune Rejection in Beta Cell Grafts

Advanced AI Tools Sift Through Complex Data to Find Gene Mutations

Method Reveals How Influenza A Takes Over Host Cell Machinery

New Base Editing Strategy Rewrites Genetic Code to Minimize Huntington's Symptoms

Type I CRISPR Systems Regulate Embedded Innate Immunity Genes in Neisseria

CRISPR Gene Editing Reveals How Enhancer Hierarchies Regulate Gene Expression

Bacteria Use CRISPR-Cas to Control Diverse Innate Defense Systems

UC San Diego and Innovative Genomics Institute Partner to Develop Cutting-Edge Genomic Tools

CRISPR Technology Enables First Successful Gene Editing in Biting Midges

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