Compound News and Research

RSS

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight loss also helps protect the liver from inflammation through a previously unknown signaling pathway, opening new possibilities for treating advanced fatty liver disease.

11 Aug 2026

Research Reevaluates Crucial Microtubule Stabilizing Protein in Dementia Progression

A protein named tau, which has been highly implicated in the world's No. 1 cause of dementia - Alzheimer's disease - and several other neurodegenerative disorders, may spur these diseases in a way that differs greatly from the pathological pathway usually ascribed to it.

7 Aug 2026

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

6 Aug 2026

Salt Toxicity Impacts Yields and Herbal Quality of Salvia Miltiorrhiza

Salt stress is one of the most destructive environmental threats to crop production, causing osmotic imbalance, ion toxicity, and oxidative damage that stunt growth and reduce yields.

3 Aug 2026

Innovative SenMayo Gene Set Consistently Identifies Diverse Senescent Cells

A series of seven Mayo Clinic studies is helping reshape scientists' understanding of senescent, or "zombie," cells - aging cells that no longer divide but remain metabolically active and release inflammatory molecules that contribute to age-related diseases.

31 Jul 2026

New Molecule Restores Muscle Repair Signal Linked to Age-Related Muscle Loss

One of the first tissues to deteriorate with aging is skeletal muscle. Weakness, scarring, internal muscle fat accumulation, and the loss of fast-twitch muscle fibers—which are crucial for rapid and forceful movements—can result from this deterioration.

27 Jul 2026

Quality Management and Traceability in Regulated Manufacturing: Moving From Silos to Integrated Data

Regulated manufacturers today face a paradox. As products become more complex and regulatory oversight more stringent, the volume of quality data required to demonstrate compliance has increased dramatically.

17 Jul 2026

Unique Odors Help Naked Mole Rat Queens Stop Power Struggles

Imagine the following scenario: A head of state enters a room and emits a scent that prevents potential rivals from even considering challenging them.

16 Jul 2026

Shifting Body Temperatures can Keep Malaria from Spreading

The fever experienced by malaria patients exposes parasites to high temperatures within blood cells.

13 Jul 2026

Researchers Map Marine Bacterial Enzyme to Tweak Therapeutic Red Pigments

Many important medicines and agricultural compounds have origins in natural products made by microorganisms.

7 Jul 2026

Study Finds Common COVID-19 Pandemic Drugs are Toxic to Marine Life

A new study published in New Contaminants suggests that several drugs widely used during the COVID-19 pandemic can be toxic to marine organisms, even at relatively low concentrations.

2 Jul 2026

Research Links Bifidobacterium animalis Metabolites to Improved Anti-Tumor T Cell Immunity

Immune checkpoint inhibitors like anti-PD-1 have transformed melanoma treatment, yet more than half of patients fail to respond or eventually develop resistance. The tumor microenvironment and the gut microbiome are increasingly recognized as critical determinants of immunotherapy outcomes.

2 Jul 2026

Chinese Researchers Map Greek Oregano Genome for Better Agriculture

Oregano belongs to the Lamiaceae family, which includes many aromatic and medicinal plants.

30 Jun 2026

Opposing Cellular States Collaborate Internally to Manage Vital Tissue Repair

Cellular senescence and stemness represent two biological entities with several opposing properties

30 Jun 2026

Scripps Scientists Find Key Vulnerability in Drug-Resistant Enterococcus Strains

Antibiotic resistance is one of the most urgent threats to global health, linked to an estimated 4.7 million deaths worldwide in 2019 alone.

30 Jun 2026

Researchers Discover Molecules Targeting Vital Cell Signaling Proteins

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals. That's why GPCRs are targeted by roughly one-third of all FDA‑approved drugs.

25 Jun 2026

DNA Barcode Technology Enables Massive Simultaneous Drug Candidate Validation

A Korean research team has launched a public drug discovery service capable of screening and validating tens of millions of compounds simultaneously.

10 Jun 2026

New Antibiotic Compound Blocks Ribosome to Starve Dangerous Pathogens

Researchers at McMaster University have discovered a new antibiotic that kills some of the world's most dangerous and drug-resistant bacteria - and does so by targeting a previously unknown vulnerability, opening the door to an entirely new class of treatments.

5 Jun 2026

Intact Gut Microbes Accelerate Selenium Excretion to Protect Against Toxic Overload

Selenium is an essential micronutrient that supports antioxidant and immune functions, yet how its metabolism is regulated by interactions between host and gut microbiota remains unclear. In a recent study, researchers from Japan used rats to investigate how gut microbiota and the host jointly manage selenium metabolism.

2 Jun 2026

Novel Cyclic Peptides Cross Cell Membranes to Fight Disease

Many diseases are driven by proteins interacting with each other inside cells. But blocking these interactions with drugs is difficult because our typic "small-molecule" drugs often prove to be too small to grip the broad, flat surfaces involved in protein-protein interactions.

1 Jun 2026