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Generative AI Model Accelerates Drug Discovery With New Antibiotic Candidate

Researchers at McMaster University have developed a new generative artificial intelligence (AI) model capable of drastically speeding up drug discovery - and, in early tests, it has already designed a brand-new antibiotic.

24 Apr 2026

Fragment-Based Drug Design Accelerates Efficient Discovery of New Medicines

Modern medicine has played a significant role in improving the length and quality of our lives. While many treatments may seem like miracles, they are the result of a lengthy, rigorous research process.

24 Apr 2026

Genomic Study Maps the Biosynthesis of Dihydromyricetin in Vine Tea

Vine tea has been consumed in China for centuries and is valued as both a beverage and a medicinal plant.

10 Apr 2026

Study Reveals Microbiota Control of Intestinal Cell Plasticity

A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and intestinal cells.

8 Apr 2026

Novel ENDOtollins Block Harmful Inflammation While Preserving Infection Response

Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

7 Apr 2026

New Genetic Pathways and Compounds Identified to Prevent Cone Degeneration

Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have identified genetic pathways and compounds capable of protecting cone photoreceptors from the degeneration that underlies conditions like age-related macular degeneration.

30 Mar 2026

Turning Plastic Bottles into Levodopa, a Key Parkinson’s Treatment

This study demonstrates the conversion of plastic bottles into levodopa using engineered bacteria, highlighting a novel approach to sustainable drug production.

25 Mar 2026

Cooperative Microbes Enable Efficient Breakdown of Harmful Plasticizers

Plastic trash has reached the world's most remote locations, from the bottom of the Mariana Trench to the summit of Everest.

19 Mar 2026

New AI Tool Guides Chemists Toward Faster Drug Discovery

Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits and suddenly, a molecule makes a promising new medicine.

10 Mar 2026

Mars Soil May Harm Living Organisms

Tardigrades, also known as water bears, could be better recognized by a new name: Tardiguardians of the Galaxy.

2 Mar 2026

Promega Unveils Cellular Target Engagement Technology Aimed at Expanding the Druggable Proteome at SLAS 2026

Promega Corporation is launching a new live-cell target engagement platform that could close a long-standing gap between biochemical and cellular assays for understudied or difficult-to-interrogate proteins.

27 Feb 2026

5,000-Year-Old Cave Bacterium Resists Antibiotics and Kills Pathogens

Psychrobacter SC65A.3, preserved in cave ice, harbors multidrug resistance genes and exhibits antimicrobial activity, offering insights into ancient resistomes.

26 Feb 2026

Engineered E. coli Produces Key Plant Compound at Record Levels

Researchers engineered E. coli to produce orsellinic acid-derived meroterpenoids, offering a sustainable alternative to traditional plant extraction methods.

25 Feb 2026

Scientists Create Charge-Free Polymer to Improve Gene Therapy Delivery

Researchers from Tokyo Metropolitan University have created a new molecule which carries DNA into biological cells, to treat or vaccinate against illnesses.

23 Feb 2026

Microbial Engineering Breakthrough Improves Supply of Promising Pharmaceuticals

Bioengineered E. coli bacteria can now produce a group of compounds with anticancer, anti-HIV, antidiabetic and anti-inflammatory activities.

18 Feb 2026

Chemical Tweaks Boost Peptide Stability and Antimicrobial Power

Antibiotic treatments are losing effectiveness against a range of common bacterial pathogens, including E. coli, K. pneumoniae, Salmonella and Acinetobacter, according to a warning issued by the World Health Organization last October.

16 Feb 2026

Mapping the Binding Energy of Histamine Receptors

G-protein-coupled receptors (GPCRs) are one of the biggest groups of cell surface proteins in the human body, recognizing hormones, neurotransmitters, and drugs.

16 Feb 2026

New Boron Compounds Enable Easier Drug Modification Without Breakdown

A major step towards simpler drug development has been taken at the University of Gothenburg. In a new study, researchers have developed stable boron-fluorine compounds that make it possible to increase the effect or reduce side effects without breaking down the medicine.

4 Feb 2026

Gut Microbial Metabolite Hippuric Acid Amplifies Immune Responses

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from berries, tea, and other plant-based foods.

31 Jan 2026

Trojan Horse Drug Works in Combination With Copper to Kill Bacteria

A research team at the University of Arizona College of Medicine – Tucson is developing a drug that works in combination with copper to kill bacteria, including those that cause MRSA, a type of staph infection that is resistant to usual treatments.

24 Jan 2026