Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Axxam and B'SYS Partner to Expand Access to Validated Ion Channel Cell Lines for High-Throughput Electrophysiology

Axxam S.p.A., a premier provider of integrated early drug discovery services, and B'SYS GmbH, a specialist in ion channel biology, are pleased to announce a strategic collaboration focused on enabling access to validated ion channel cell lines for hit and lead identification through high-throughput electrophysiological screening.

From Axxam S.p.A 8 Sep 2025

Scientists Identify Human Proteins Essential for SARS-CoV-2 Infection and Replication

Despite vaccines and treatments, SARS-CoV-2-the virus that causes COVID-19-continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood.

5 Sep 2025

Novel Fluorescent Reporter Technology Enables Real-Time Visualization of Apoptosis Inside Cells

Cells in our body are programmed to die after a certain period of time-a natural process known as apoptosis or "cell suicide."

4 Sep 2025

Human-Derived 3D Skin Model May Replace Animals In Wound Studies

Engineered 3D skin model successfully simulates early wound healing, offering insights into inflammatory responses and potential therapeutic applications.

3 Sep 2025

Cornell Study Reveals Early Genetic Differences Between Male and Female Embryos

Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization.

1 Sep 2025

GEMORNA Platform Generates Novel mRNA Sequences With Superior Drug Properties

Raina Biosciences Inc., ("Raina"), an mRNA technology and therapeutics company, today announced the publication of data from its generative AI platform in Science.

28 Aug 2025

Emory Chemists Boost Synthesis of Vinylic Ethers for Drug Discovery

A new approach to an established reaction boosts the ability to synthesize vinylic ethers - key building blocks for many molecules important to human health.

28 Aug 2025

Aptamer Group Introduces Novel Biomarker Discovery Service

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, today announced the launch of its biomarker discovery service, offering researchers in pharmaceutical, biotechnology, and diagnostic development an innovative approach to identify and validate new disease markers.

28 Aug 2025

Mitsui, QSimulate, and Quantinuum Launch “QIDO”: A Quantum-Integrated Chemistry Platform Targeting Faster Drug and Materials Discovery

Mitsui & Co., Ltd. (“Mitsui”), QSimulate, and Quantinuum today announced the launch of a new quantum-integrated chemistry platform, QIDO (Quantum-Integrated Discovery Orchestrator).

From Quantinuum Ltd 22 Aug 2025

Small Protein LptM Plays Key Role in Assembling Protective Outer Membrane in Bacteria

Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria.

5 Aug 2025

Amino Acids Guide Cell Responses to Drugs Through a Complex Network

Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like bricks that communicate with each other within a structure.

17 Jul 2025

Study Reveals Surprising Redundancy in Staph Metabolism

In the ongoing battle against antibiotic-resistant bacteria, MSU researchers have made a discovery that could reshape how we target deadly pathogens like staph infections.

17 Jul 2025

New Microchip Maps Antibody Responses Using Just a Drop of Blood

A new microchip invented by Scripps Research scientists can reveal how a person's antibodies interact with viruses-using just a drop of blood.

14 Jul 2025

ColdBrew Enhances Accuracy of Protein Water Mapping for Drug Design

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers function.

30 Jun 2025

New Technique Enhances Three Dimensional Immunolabeling in Thick Tissues

Three dimensional immunohistochemistry (3D-IHC) has transformed our ability to visualize the spatial arrangement of cells and molecules in intact tissues.

20 Jun 2025

Novel Strategy for Combating High-Fat Diet-Induced Metabolic Dysfunction

Research on receptor FFA2 reveals how different activators influence metabolic processes, paving the way for innovative treatments for diabetes and obesity.

20 Jun 2025

Bio-Rad Extends Anti-Idiotypic Antibody and SpyCatcher Reagent Ranges for Bioanalysis and Antibody Drug Development

Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics products, today extended its range of recombinant monoclonal anti-idiotypic antibodies with the introduction of antibodies specific to pertuzumab (Perjeta), guselkumab (Tremfya), canakinumab (Ilaris), belimumab (Benlysta), and the bispecific drug emicizumab (Hemlibra).

18 Jun 2025