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St. Jude Scientists Discover Hidden Binding Pocket in Nuclear Receptors

A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, revealing a much-needed new therapy route for this important class of drug targets.

7 Nov 2025

Breakthrough Small Molecule Offers New Hope for Diabetes Treatment

Researchers from the University at Albany and NYU Grossman School of Medicine have found a way to block a key cellular pathway known to drive chronic inflammation and impaired wound healing in people with diabetes.

31 Oct 2025

Retinal Implant Restores Sight for Patients With Macular Degeneration

A wireless photovoltaic implant shows promise in restoring central vision for patients with macular degeneration, enhancing visual acuity and independence.

29 Oct 2025

Scientists Reveal How Nanovaccines Boost the Immune Fight Against Aggressive Breast Cancers

Nanovaccines show promise in breast cancer therapy, enhancing immune activation and targeting cold tumors, particularly in challenging triple-negative cases.

24 Oct 2025

Ingestible Bioprinter Revolutionizes Possibilities for Non-Invasive Tissue Repair

The MEDS device enables non-invasive tissue repair in the GI tract, utilizing innovative bioprinting techniques for effective treatment of internal lesions.

23 Oct 2025

Cracking the Code of T Cell Expansion Inside Tumors

The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key to the success of modern day cancer immunotherapies.

22 Oct 2025

PapB Could Make Ozempic-Style Drugs Stronger and Last Longer

Chemistry researchers at the University of Utah have discovered an enzyme referred to as PapB, which is capable of "tying off" therapeutic peptides, drugs resembling proteins, into compact rings, a process termed macrocyclization.

17 Oct 2025

Combating Influenza A Virus with CRISPR and Human Lung Organ Chips

The Influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally.

16 Oct 2025

GlyTR Therapeutics Unveils Groundbreaking Glycan-Targeting Cancer Immunotherapy

GlyTR Therapeutics, a biotech company pioneering development of glycan-targeting cancer immunotherapies, announced the publication of its foundational technology in the journal, Cell.

14 Oct 2025

Masks Attenuate Exposure of Traffic Pollutants’ Adherence to Red Blood Cells

Inhaled traffic pollutants attach to red blood cells, facilitating systemic transport. Wearing FFP" masks lessens this exposure, emphasizing the protective role of masks against air pollution.

10 Oct 2025

Antibody 04_A06 Neutralizes Nearly All Tested HIV Variants in Laboratory Studies

A Cologne-led research team has discovered the antibody 04_A06, which neutralizes the human immunodeficiency virus (HIV) in almost all tested variants in vitro and even overcomes typical resistance mechanisms.

7 Oct 2025

Microbial Molecule Controls Cancer Progression and Boosts Chemotherapy

An international team of scientists led by researchers from the MRC Laboratory of Medical Sciences (LMS), Imperial College London, and the University of Cologne discovered that microbes associated with tumors produce a molecule that can control cancer progression and improve chemotherapy efficacy.

15 Sep 2025

A Molecular Magnifying Glass for Tracking Protein Misfolding in Living Cells

A novel strategy developed at Rice University allows scientists to zoom in on tiny segments of proteins inside living cells, revealing localized environmental changes that could indicate the earliest stages of diseases such as Alzheimer's, Parkinson's and cancer.

15 Sep 2025

Researchers Develop New Technique to Detect Causality in Neural Spike Trains

Understanding the brain's functional architecture is a fundamental challenge in neuroscience. The connections between neurons ultimately dictate how information is processed, transmitted, stored, and retrieved, thus forming the basis of our cognitive functions.

10 Sep 2025

New Research Highlights a More Efficient CAR T Treatment

This review article focuses on the transformative potential of in vivo CAR T cell treatment in overcoming the constraints of standard CAR T cell production.

8 Sep 2025

Scientists Identify Human Proteins Essential for SARS-CoV-2 Infection and Replication

Despite vaccines and treatments, SARS-CoV-2-the virus that causes COVID-19-continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood.

5 Sep 2025

BioDlink Expands Ecosystem Alliance to Empower Biotech Innovators Worldwide

As BioDlink, a leading global CDMO, affirms its commitment to strategic alliances to support biotech innovation worldwide as it marks 15 years of operations.

From BioDlink 5 Sep 2025

Novel Fluorescent Reporter Technology Enables Real-Time Visualization of Apoptosis Inside Cells

Cells in our body are programmed to die after a certain period of time-a natural process known as apoptosis or "cell suicide."

4 Sep 2025

AI Tool for Designing Antibiotics from Scratch

In a recent Cell Biomaterials study, University of Pennsylvania researchers offer AMP-Diffusion, a generative AI tool for creating tens of thousands of novel antimicrobial peptides (AMPs) — short strings of amino acids that serve as the building blocks of proteins — with bacteria-killing capability.

3 Sep 2025

Tackling KRAS Mutations Unlocks New Hope for Pancreatic Cancer Patients

Accounting for nearly 90% of all pancreatic cancers, pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of just 13%. Late-stage diagnosis, limited surgical options, and toxic chemotherapy regimens contribute to its poor outcomes.

2 Sep 2025