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New Drug Combo Shows Promise Against Aggressive Leukemia in Landmark Study

A novel drug combination targeting LSD1 and GSK3 shows promise in treating acute myeloid leukemia by promoting cell differentiation and reducing tumor growth.

28 Apr 2025

Unraveling the Role of Long Noncoding RNAs in the Tumor Microenvironment

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to influence tumorigenesis, progression, and metastasis.

25 Apr 2025

Researchers Develop Quantum-AI Platform to Predict Antimicrobial Resistance in Salmonella

SARPLLM leverages large language modeling and quantum algorithms to predict Salmonella AMR, offering robust analysis and user-friendly data visualization tools.

17 Apr 2025

Lab-Grown Lung Cancer Cells to Unlock Targeted Treatments

Scientists at the Cancer Research Manchester Institute have created a new model of Lung Squamous Cell Carcinoma (LUSC), a common type of lung cancer, to study the development, activity, and vulnerabilities of the disease.

9 Apr 2025

Carbon Dot-Based Fluorosensor Shows Superior Performance in Enterovirus RNA Detection

Scientists from the University of Jyväskylä's Nanoscience Center in Finland have introduced a novel, label-free ratiometric fluorosensor intended for the sensitive and specific detection of enteroviral RNA.

7 Apr 2025

DNA Aptamers Offer Precision Attack Against Leukemia Stem Cells

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.

4 Apr 2025

Scientists Build Live African Swine Fever Virus From Synthetic DNA Using CRISPR

Utilizing CRISPR-Cas9, scientists reconstitute live African swine fever virus from synthetic genomes, accelerating vaccine development for this deadly virus.

2 Apr 2025

Novel AI Models Enhance Disease Diagnosis and Pathogen Identification

With the widespread availability of AI tools, numerous fields within the technical and natural sciences are experiencing rapid advancements.

1 Apr 2025

Ice Baths May Help Boost Your Cells' Ability to Handle Stress

Ever wondered what happens to your body when you take those trendy ice baths? Scientists at the University of Ottawa just found out, and it's pretty fascinating.

29 Mar 2025

Researchers Unearth Powerful New Antibiotic from Soil

Researchers at McMaster have made a significant discovery that may be the answer to combating antimicrobial resistance, nearly thirty years after the last time a novel class of antibiotics was brought to market.

28 Mar 2025

AI Revolutionizes Cell Analysis for Personalized Cancer Treatment

A groundbreaking artificial intelligence (AI)-driven neural network has been developed to swiftly analyze and interpret millions of cells from patient samples, enabling predictions of molecular alterations within tissues.

19 Mar 2025

Bispecific antibodies for SARS-CoV-2 variant neutralization

Bispecific antibodies targeting multiple SARS-CoV-2 sites offer enhanced neutralization against emerging variants, advancing COVID-19 treatment strategies.

14 Mar 2025

New Cannabinoid Drug Brings Hope For Treating Chronic Pain Without Addiction

VIP36, a new CB1 agonist, targets a cryptic pocket to provide analgesia for chronic pain while minimizing side effects and avoiding opioid-related risks.

13 Mar 2025

Circular RNA's Transformative Role in Tumor Biology and Treatment

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

10 Mar 2025

Minoryx Announces Dosing of the First Patient with Leriglitazone in the Phase 2a Study in Rett Syndrome (TREE Study)

Minoryx Therapeutics, a late-stage biotech company focused on the development of therapies for orphan central nervous system (CNS) disorders, today announces that the first patient in the TREE study has been dosed with leriglitazone.

6 Mar 2025

Mapping Bacterial Responses to Reactive Nitrogen and Oxygen Species

A study in Microbiological Research explored the impact of varying ratios of Reactive Nitrogen Species (RNS) and Reactive Oxygen Species (ROS) on pathogenic bacteria, including Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa.

28 Feb 2025

Innovative Screening Method Targets Specific Tissues for Drug Delivery

A method developed by a research group at Tampere University seeks specific molecules that can target desired tissues through the bloodstream and penetrate tissues by passing through cells.

27 Feb 2025

Researchers Develop Mycobacteria Strains with Kill Switches for Safer TB Vaccines

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with "kill switches" that can be triggered to stop the bacteria after they activate an immune response.

26 Feb 2025

New Strategy Targets Bacterial Communication to Combat Pseudomonas aeruginosa

Pseudomonas aeruginosa is notorious for its role in food spoilage and infections, posing a significant threat to both food safety and human health.

26 Feb 2025

Harbour BioMed and Insilico Collaborate on Advanced AI-Driven Antibody Discovery

Harbour BioMed (HKEX: 02142, the "Company"), a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on immunology and oncology, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced a strategic collaboration to accelerate the discovery and development of innovative therapeutic antibodies, leveraging their respective technological strengths in antibody discovery and artificial intelligence.

22 Feb 2025