Efficacy News and Research

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Single-cell atlas reveals how melanoma evades the immune system

Integrative analysis of immune ecotypes in skin cancers highlights metabolic reprogramming and macrophage polarization as key factors in melanoma progression.

11 Feb 2026

Understanding Inter-Micellar Interactions Governing Drug Nanocarriers

Polymer micelles are tiny, self-assembled particles that are revolutionizing the landscape of drug delivery and nanomedicine.

10 Feb 2026

Chemistry Breakthrough Improves Gene Delivery, Reduces Side Effects

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

5 Feb 2026

Postmortem Human Retinas Recover Neural Light Signals

The ability to restore light responses in human retinas postmortem offers a novel model for studying retinal recovery and developing vision-restoring therapies.

5 Feb 2026

Gravity-Driven Microfluidic Platform Enhances Immune Cell-Tissue Co-Culture

Advanced in vitro models such as organ-on-chip systems aim to replicate human physiology more accurately than conventional cell cultures. However, most existing platforms struggle to incorporate circulating cells like immune cells or circulating tumor cells.

3 Feb 2026

Integrated Micro-Optical System Revolutionizes Tissue Monitoring

Microphysiological systems and organ-on-chip technologies are increasingly used to model human tissues outside the body, offering alternatives to animal experiments and traditional cell cultures.

2 Feb 2026

Microfluidic Technology Creates Realistic 3D Cell Environments for Research

Most cells in the human body exist in complex three-dimensional environments, yet they are still commonly studied on flat plastic dishes.

30 Jan 2026

Bioengineered Lymphatic Tissue Shows Promise in Treating Secondary Lymphedema

The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes.

27 Jan 2026

A Week of 40-Hz Sound Triggers Long-Lasting Amyloid Changes in Monkeys

Forty-hertz auditory stimulation in aged monkeys doubles CSF amyloid-β levels, offering insights into non-invasive strategies for Alzheimer's disease treatment.

15 Jan 2026

New Technique Measures How Effectively Antibiotics Kill Bacteria

Drugs that act against bacteria are mainly assessed based on how well they inhibit bacterial growth under laboratory conditions.

12 Jan 2026

Specialized Immune Cells Grown in Labs Offer Hope for Autoimmune Patients

Researchers at the University of British Columbia (UBC) have made a significant discovery regarding the cultivation of specialized immune cells, facilitating the development of readily available off-the-shelf cell therapies aimed at treating cancer, autoimmune diseases, and additional conditions.

9 Jan 2026

Microneedle Patches May Unlock Safer, Localized Cancer Immunotherapy

This review highlights the potential of natural polysaccharide microneedles in cancer immunotherapy, focusing on localized treatment and immune activation.

7 Jan 2026

Blocking Retinoic Acid Pathway Improves Dendritic Cell Anti-Tumor Function

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic acid-compromises both the body's normal anti-cancer immune response and, in a different context, the efficacy of a promising type of cancer vaccine.

6 Jan 2026

m-RNA and Immunostimulant Activate CAR-Macrophages in Cancer Cells to Fight Cancer

Immune cells (macrophages) capable of combating cancer exist within tumors in the human body, but they are unable to fulfill their functions adequately due to tumor suppression.

2 Jan 2026

Computational Brain Model Predicts Errors, Uncovers Previously Unseen Neurons

A new computational model of the brain based closely on its biology and physiology not only learned a simple visual category learning task exactly as well as lab animals, but even enabled the discovery of counterintuitive activity by a group of neurons that researchers working with animals to perform the same task had not noticed in their data before, said a team of scientists at Dartmouth College, MIT, and the State University of New York at Stony Brook.

30 Dec 2025

Mitochondrial Protein That “Erases” Huntington’s Aggregates

DGIST has made a groundbreaking announcement: a research team, under the guidance of professors Jiwon Um and Jaewon Ko, has achieved a global first by elucidating the function of ‘ClpB.’

29 Dec 2025

Antibiotic Resistance: A Global Crisis Threatening Modern Medicine's Future

Once a medical miracle, antibiotics are now losing their power. Across the world, common infections are becoming harder-and sometimes impossible-to treat. This new review paints a sobering picture of global antimicrobial resistance (AMR), tracing how bacteria and fungi are evolving faster than medicine can respond.

24 Dec 2025