Electron Microscopy News and Research

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Higher-Order Receptor Clustering Acts as Hidden Lymphangiogenic Signal Amplifier

Lymphatic vessels act as the body's "drainage system," collecting excess fluid from tissues. When lymphatic drainage is impaired because lymphatic vessels are underdeveloped, damaged, or dysfunctional, lymphedema can develop, causing swelling, particularly in the arms and legs.

6 Oct 2026

Targeting Host Cellular Repair Mechanisms Enhances Tissue Resistance to Infection

Epithelial cells form the body's frontline barriers, helping keep microbes, toxins, and other harmful substances out. Yet these protective cells are constantly exposed to threats, including microbial infections.

6 Oct 2026

Electron Microscopy Imaging Confirms Piezo1-Dependent Axonal Sheath Structural Remodeling

Researchers at Upstate Medical University have identified a key mechanism that helps determine the length of myelin, the protective coating that surrounds many nerve fibers and allows signals to travel efficiently through the nervous system.

1 Oct 2026

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Using cryo-electron microscopy, researchers at the Max Delbrück Center have revealed how muscle cell calcium channels open synchronously. The findings, published in "Nature Communications," may explain a mechanism behind serious muscle diseases.

25 Sep 2026

Trans-spliceosome Architecture Maps Evolutionary Divergence in Eukaryotic RNA Processing

A study conducted between the University of Liège and Rockefeller University reveals, with near-atomic precision, the three-dimensional structure and function of a gigantic molecular machine essential to the survival of trypanosomatid parasites, which cause serious diseases in humans, animals and plants.

24 Sep 2026

Cryo-EM Captures Interactions Between BRD4 Bromodomains and Nucleosomal DNA

Researchers have uncovered a new 3D structure of a cancer-linked protein bound to its cellular partner, detailing how it attaches to chromosomes and offering key insights for future disease treatments.

16 Sep 2026

Research Reveals Molecular Link Between Matrix Protein Motifs and Ameloblast Organization

Tooth enamel looks simple from the outside and consists of a hard, smooth surface built to withstand years of wear.

12 Sep 2026

New Insights Into How Giant-Nucleus Cells Promote Early-Stage Cancer Growth

Iron is an essential micronutrient, but excess iron can damage cells and increase cancer risk. While many cells die from iron-induced oxidative stress, a subset survives and may become cancerous. Previously, the identity of these surviving cells was unclear.

11 Sep 2026

Key Cellular Complexes Drive Protein Localization Within Resistant Bacterial Membranes

Gram-negative bacteria are responsible for causing several infections that are hard to treat, owing to their high resistance to antibiotics.

7 Sep 2026

RNA Polymerase Successfully Transcribes an Expanded Genetic Alphabet

All known life on earth utilizes the same genetic alphabet, consisting of four letters. Now, researchers at University of California San Diego have demonstrated that one of biology's most essential enzymes can accurately read and transcribe an expanded, eight-letter genetic alphabet.

4 Sep 2026

Researchers Unlock Key Potassium Channel That Controls Plant Stalk Elongation

Potassium (K) is one of the three essential nutrients for plants. It plays a critical role in a wide range of processes, including cell growth, photosynthesis, and regulation of water balance. Plants take up K from the soil and circulate it throughout their bodies via molecules called K+ channels.

3 Sep 2026

Colorectal Cancer and Nerve Damage: A Hidden Link Uncovered in Mice and Primates

Colorectal tumors trigger inflammatory nerve damage, suggesting cancer itself may be a risk factor for neuropathy in survivors, independent of treatments.

27 Aug 2026

Powerful Imaging Technique Captures Gene Transcription Inside Living Organisms

All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the molecules responsible for helping build proteins that keep organisms alive.

21 Aug 2026

Study Reveals Previously Unknown Mechanism of RNA Synthesis Shared Across Life Forms

Scientists have long been fascinated by two promising classes of antibiotics that disable RNA polymerase (RNAP).

13 Aug 2026

New Study Reveals How Genetic Mutations Hijack the Parkinson's LRRK2 Switch

Researchers at Weill Cornell Medicine have uncovered how a key Parkinson's protein called LRRK2 shifts between inactive and active forms, revealing the structural changes that enable certain mutations to push the protein into an overactive state.

11 Aug 2026

Researchers Uncover Molecular Defenses in Cold-Resilient Loquat

Loquat (Eriobotrya japonica) is an evergreen fruit tree whose winter growth and flowering make it especially vulnerable to sudden freezes.

10 Aug 2026

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

6 Aug 2026

Protein Discovery Sheds Light on Scarring Diseases

UK and US scientists have uncovered an important piece of the puzzle on the signaling pathway that causes damaging scar tissue to build up in the body, raising hopes for future treatments.

5 Aug 2026

Dynamic Structural Flexibility of Human Norovirus Evade the Immune System

Human norovirus is the leading cause of acute gastroenteritis worldwide and is estimated to infect 600–700 million people each year. Despite its enormous public health impact, no effective antiviral drugs are currently available.

5 Aug 2026

New Research Bypasses Rapid Fungicide Resistance Through Cell Wall Disruption

Powdery mildew is among the most widespread crop diseases, affecting cereals, grapes, cucurbits, tomatoes, fruit crops, and ornamentals in fields and greenhouses.

5 Aug 2026

Electron Microscopy News and Research

Higher-Order Receptor Clustering Acts as Hidden Lymphangiogenic Signal Amplifier

Targeting Host Cellular Repair Mechanisms Enhances Tissue Resistance to Infection

Electron Microscopy Imaging Confirms Piezo1-Dependent Axonal Sheath Structural Remodeling

Cryo-ET Reveals Native Membrane Architecture of Synchronous RyR1 Calcium Channels

Trans-spliceosome Architecture Maps Evolutionary Divergence in Eukaryotic RNA Processing

Cryo-EM Captures Interactions Between BRD4 Bromodomains and Nucleosomal DNA

Research Reveals Molecular Link Between Matrix Protein Motifs and Ameloblast Organization

New Insights Into How Giant-Nucleus Cells Promote Early-Stage Cancer Growth

Key Cellular Complexes Drive Protein Localization Within Resistant Bacterial Membranes

RNA Polymerase Successfully Transcribes an Expanded Genetic Alphabet

Researchers Unlock Key Potassium Channel That Controls Plant Stalk Elongation

Colorectal Cancer and Nerve Damage: A Hidden Link Uncovered in Mice and Primates

Powerful Imaging Technique Captures Gene Transcription Inside Living Organisms

Study Reveals Previously Unknown Mechanism of RNA Synthesis Shared Across Life Forms

New Study Reveals How Genetic Mutations Hijack the Parkinson's LRRK2 Switch

Researchers Uncover Molecular Defenses in Cold-Resilient Loquat

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Protein Discovery Sheds Light on Scarring Diseases

Dynamic Structural Flexibility of Human Norovirus Evade the Immune System

New Research Bypasses Rapid Fungicide Resistance Through Cell Wall Disruption

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