Gene Editing News and Research

RSS

Prime Assembly Approach Transforms Gene Therapy With Large DNA Inserts

New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment from cancellation of disease-causing mutations to replacement of an entire gene, scientists say.

30 Apr 2026

Gene Editing Reprograms Immune System to Produce Therapeutic Proteins

An innovative gene-editing strategy could establish a new way for the body to manufacture therapeutic proteins-including certain kinds of highly potent antibodies the are naturally difficult to produce-by reprogramming the immune system itself.

20 Apr 2026

New Tool Directly Transfers Cytoplasm and Organelles Between Living Cells

Cells are not isolated units; they continuously exchange proteins, genetic material, and even entire organelles with their neighbors.

6 Apr 2026

New Gene-Editing Approach Eliminates Painful Crises in Sickle Cell Disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

2 Apr 2026

Newly Discovered CRISPR System Activates Genes Without Cutting DNA

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR gene-editing systems that merely find and cut DNA.

26 Mar 2026

New Base Editing Tool Reduces Unwanted DNA Bystander Mutations

The trajectory of base editing has been remarkable, progressing from the laboratory to patient care, treating debilitating or terminal illnesses, in less than a decade.

19 Mar 2026

New Gene-Editing Strategy to Eliminate Aggressive Cancer Cells

The initiation and severity of cancer are associated with the atypical behavior of specific genes, referred to as oncogenes. The most recognized of these changes is mutation; however, it is not the sole alteration.

9 Feb 2026

Cellares to Expand Automated Manufacturing to Gene-Edited Stem Cell Therapies

Cellares, the first Integrated Development and Manufacturing Organization (IDMO), today announced a collaboration with the Stanford Center for Definitive and Curative Medicine (CDCM) and Stanford Innovative Medicines Accelerator (IMA) to automate manufacturing and release testing for gene-edited hematopoietic stem cell (HSC) therapies, expanding the application of Cellares' automation platforms beyond T cell therapies into a new cell modality.

From Cellares 8 Feb 2026

Human Neurons Reveal Why Some Cells Resist Tau Protein Buildup

New research by UCLA Health and UC San Francisco has uncovered why certain brain cells are more resilient than others to the buildup of a toxic protein that is a hallmark of Alzheimer's disease and related dementias, potentially leading to new targets for therapies or treatments.

31 Jan 2026

Expanding CRISPR to Tackle Incurable Skin Diseases

Gene-editing techniques such as CRISPR have enabled new treatments for previously incurable diseases. Researchers at the University of British Columbia are now expanding those capabilities to include the skin for the first time.

28 Jan 2026

Study Reveals How Cells Compensate for Missing Chromosomes

A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy.

4 Dec 2025

New Genetic Pathway Explains Why Some Citrus Fruits Taste Less Sour

The characteristic sour-sweet balance of citrus fruits is largely defined by citric acid accumulation in the vacuoles of juice sacs.

10 Nov 2025

New Retron-Based Gene Editing Method Corrects Multiple Disease-Causing Mutations

Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person's genome, often with enough variation that even two individuals who share the same disorder might have a different combination of mutations.

24 Oct 2025