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Telomerase Protects Against Chronic Disease Beyond Cellular Aging

A protein long studied for its connection to aging may also play a key role in protecting the body from chronic disease, according to new research from the laboratory of Mikhail Kolonin, PhD, published in Aging Cell.

29 May 2026

Molecular Blueprint Shows How Vital Gene Regulation Complexes Form

While scientists have known for over two decades that all cells use a strategy called RNA interference to regulate gene expression, a new study is the first to describe how a specific protein manages the step-by-step process of assembling the molecular complex that performs the regulatory job.

27 May 2026

Genomewide CRISPR Screen Reveals Unexpected Structural Protein Link Behind Chronic Colon Inflammation

Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor formation, potentially leading to colorectal cancer, by secreting a toxin that damages the lining of the colon. But until now, the exact mechanism the toxin uses to latch onto those cells remained a mystery.

25 May 2026

Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping

23 May 2026

Analysis Reveals Blurred Neural Patterns During Failed Cognitive Switches

Most people have experienced the feeling: switching from one task to another, only to find the brain momentarily stuck in the old mode of thinking. Sometimes, even after realizing a strategy no longer works, the mind keeps returning to it anyway.

21 May 2026

Low-Oxygen Environments Enhance Engraftment and Function of Transplanted Stem Cells

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that human hematopoietic stem cells are highly sensitive to oxygen, which can dictate how the cells grow and function.

19 May 2026

Prime Assembly Enables Precise Insertion of Large DNA Segments Into the Genome

Researchers at UMass Chan Medical School have developed a gene editing technology that allows for the precise and efficient insertion of very large DNA segments into the human genome.

13 May 2026

Prime Assembly Approach Transforms Gene Therapy With Large DNA Inserts

New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment from cancellation of disease-causing mutations to replacement of an entire gene, scientists say.

30 Apr 2026

Protein Adgrl2 Regulates Brain Synapses and Blood Vessel Integrity

The communication network in the developing brain builds when neurons partner up to form contact points called synapses, allowing signals to pass form one cell to another.

28 Apr 2026

Kinesin Motor Protein Variations Control Cargo Specificity in Neuronal Transport

Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations.

13 Apr 2026

AI Predicts Viral Mutations to Design Future-Proof Vaccines

The wave-shaped chart Ratul Chowdhury pulls up on a computer monitor in his office captures the evolutionary cat-and-mouse game his research lab is up against.

13 Apr 2026

Non-Coding DNA Mutations Identified as Cause of Rare Neonatal Diabetes

Scientists have found new genetic causes for diabetes in babies – in a part of the genome that has historically been overlooked in genetic studies.

10 Apr 2026

New Method Reveals Genome Changes and Activity in Cancer

Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like cancer.

9 Apr 2026

Study Identifies Stemness Checkpoint Controlling Stem Cell Identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages.

9 Apr 2026

Nonviral Nanoparticles Show Promise for Safer Gene Delivery Methods

In a demonstration that helps pave the way for gene therapies with fewer side effects, several human cell types were genetically modified with protein nanoparticles designed at University of Michigan Engineering and Michigan Medicine.

1 Apr 2026

Tick-Borne Parasite Treatment Benefits From Replacing Infected Red Cells

In a multicenter study, researchers at Mass General Brigham found that exchange transfusion was associated with markedly improved outcomes compared with standard treatment for a potentially life-threatening tick-borne infection

31 Mar 2026

New PanNDA Atlas Maps Protein Networks in Neurodegenerative Diseases

Neurodegenerative diseases form a tangled biological web with overlapping molecular signatures and symptoms. To decode this complexity, a multi-institute collaboration led by St. Jude Children's Research Hospital scientists developed the pan-neurodegeneration atlas (PanNDA).

24 Mar 2026