Metabolite News and Research

RSS

Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis.

30 Sep 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

Open Sesame: Can Plants Acquire Genes from the Species They Parasitize On?

A new study shows how Cuscuta plants acquire and repurpose a functional gene from a host species through horizontal gene transfer, thereby enhancing metabolic diversity.

8 Sep 2026

Advanced Computational Methods Map Metabolite Binding Proteins Across Cellular Contexts

Endogenous metabolites participate in nearly every fundamental biological process, serving not only as metabolic intermediates but also as signaling molecules that influence physiology and disease.

1 Sep 2026

International Team Establishes Standardized Nomenclature For Selenosugar Research

Selenosugars are the major urinary metabolites responsible for the physiological excretion of selenium. Understanding selenium metabolism relies on accurately detecting and identifying selenosugars.

21 Aug 2026

New Oral Nanomedicine Leverages Gut Metabolites to Destroy Tumors

A joint research team-led by Professor Young Seok Cho from the School of Medicine, alongside Professor James J. Moon from the University of Michigan-has successfully developed the world's first oral, microbiome-based nanomedicine.

12 Aug 2026

New Microbiome Study Reveals Natural Defense Mechanism Restricting Candida Albicans

A metabolic byproduct formed when gut bacteria break down dietary fiber appears to protect against dangerous fungal infections common in immunocompromised patients, a study led by UT Southwestern Medical Center researchers shows.

15 Jul 2026

Gut Bacteria Metabolites Successfully Boost Immune Response to Melanoma Tumors

A new study from a team including University of Nebraska–Lincoln researchers is the first to show metabolites produced by certain bacteria in the gut can positively impact the body's immune response to cancer.

15 Jul 2026

Study Identifies Novel Metabolic Pathway Driving Cancer Gene Activation

A team at Roswell Park Comprehensive Cancer Center has identified a novel metabolic pathway that plays a key role in enabling cancer to progress through gene activation.

9 Jul 2026

Gut Microbiome Signatures Correlate With Clinical Efficacy in Immunotherapy Outcomes

Cancer remains notoriously difficult to treat, partly because tumors co‑opt their surrounding environment, including the resident microbiota, to evade immune surveillance and resist conventional therapies.

9 Jul 2026

Research Links Bifidobacterium animalis Metabolites to Improved Anti-Tumor T Cell Immunity

Immune checkpoint inhibitors like anti-PD-1 have transformed melanoma treatment, yet more than half of patients fail to respond or eventually develop resistance. The tumor microenvironment and the gut microbiome are increasingly recognized as critical determinants of immunotherapy outcomes.

2 Jul 2026

New Method Dissects Light Signaling and Heme Pathways in Chloroplast Formation

For plants, light is an important environmental factor not only as a source of energy for photosynthesis but also as a signal for capturing environmental information. Light signals are sensed by photoreceptor proteins called phytochrome. The amino acids that make up proteins are transparent and cannot absorb visible light.

8 Jun 2026

Study Connects Lysosomal Lipid Movement Directly to Cellular Growth Signaling

While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite. Some tumor cells use as much cholesterol as they can access to accelerate their growth beyond the capabilities of normal cells.

25 May 2026

Epigenetic Engineering Boosts Stable Production of Safe Monascus Pigments

This study was led by Professor Yi Wang and Professor Weiming Zhu from the School of Medicine and Pharmacy, Ocean University of China.

15 May 2026

Web-Based Platform Facilitates Chemical Structure Queries in Metabolomics

An international team led by researchers at University of California San Diego and University of California, Riverside has developed a free, web‑based platform designed to make public metabolomics data more accessible.

15 May 2026

New Single-Cell Technique Reveals Why Bacteria Survive Antibiotics

SinBactM's innovative approach to single-bacterium metabolomics reveals distinct metabolic states, enhancing understanding of antibiotic resistance in bacteria.

6 May 2026

Metabolic Pathway Loss Makes Cancer Cells Vulnerable to PARP Drugs

Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern Medical Center researchers shows.

5 May 2026

New Genetic Pathways Linked to Cardiometabolic Disease Identified

A study published today in PLOS Medicine has identified two new genetic pathways that contribute to cardiometabolic disease, which includes heart disease, obesity and diabetes.

24 Apr 2026

Study Reveals the "Black Box" of Protein Quality Control in the ER

Over the past few years, Kivanç Birsoy of Rockefeller University and his colleagues in the Laboratory of Metabolic Regulation and Genetics have uncovered amazing information about the antioxidant glutathione, which has numerous vital functions in the body, including eliminating free radicals and repairing cellular damage.

20 Apr 2026

Genomic Study Maps the Biosynthesis of Dihydromyricetin in Vine Tea

Vine tea has been consumed in China for centuries and is valued as both a beverage and a medicinal plant.

10 Apr 2026

Metabolite News and Research

Further Reading

Gut-Derived Neutral Ceramidase Regulates MASH Through Microbial and Epithelial Signaling

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

Open Sesame: Can Plants Acquire Genes from the Species They Parasitize On?

Advanced Computational Methods Map Metabolite Binding Proteins Across Cellular Contexts

International Team Establishes Standardized Nomenclature For Selenosugar Research

New Oral Nanomedicine Leverages Gut Metabolites to Destroy Tumors

New Microbiome Study Reveals Natural Defense Mechanism Restricting Candida Albicans

Gut Bacteria Metabolites Successfully Boost Immune Response to Melanoma Tumors

Study Identifies Novel Metabolic Pathway Driving Cancer Gene Activation

Gut Microbiome Signatures Correlate With Clinical Efficacy in Immunotherapy Outcomes

Research Links Bifidobacterium animalis Metabolites to Improved Anti-Tumor T Cell Immunity

New Method Dissects Light Signaling and Heme Pathways in Chloroplast Formation

Study Connects Lysosomal Lipid Movement Directly to Cellular Growth Signaling

Epigenetic Engineering Boosts Stable Production of Safe Monascus Pigments

Web-Based Platform Facilitates Chemical Structure Queries in Metabolomics

New Single-Cell Technique Reveals Why Bacteria Survive Antibiotics

Metabolic Pathway Loss Makes Cancer Cells Vulnerable to PARP Drugs

New Genetic Pathways Linked to Cardiometabolic Disease Identified

Study Reveals the "Black Box" of Protein Quality Control in the ER

Genomic Study Maps the Biosynthesis of Dihydromyricetin in Vine Tea

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

RecentIndustryFocuses

Editorial Focus eBook - Biopharmaceuticals (2nd edition)

Improving Cell Culture Efficiency with Image-Guided Automation

Improving Scalability in Organoid Research

Cosmetic Formulation and Manufacturing

Latest in Genomics