Oxidative Stress News and Research

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Oxidative Stress is a condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma.

New Insights Into How Giant-Nucleus Cells Promote Early-Stage Cancer Growth

Iron is an essential micronutrient, but excess iron can damage cells and increase cancer risk. While many cells die from iron-induced oxidative stress, a subset survives and may become cancerous. Previously, the identity of these surviving cells was unclear.

11 Sep 2026

SMART Researchers Discover First PLP-Dependent Enzyme That Influences Bacterial Protein Production

Researchers from the Singapore-MIT Alliance for Research & Technology’s (SMART) Antimicrobial Resistance (AMR) interdisciplinary research group, alongside collaborators from Massachusetts Institute of Technology (MIT), Nanyang Technological University (NTU Singapore), and institutions in the United States, Poland, and France, have discovered aminovaleramididine synthetase (AvaS), the first identified pyridoxal phosphate (PLP)-dependent enzyme responsible for producing a chemical modification linked to how bacteria respond to metabolic stress.

10 Sep 2026

First Chromosome-Level Genome Unveils Blueprints of Valued Medicinal Compounds

Spuriopimpinella brachycarpa, known locally as Dayeqin or Shanqincai, has long been used in traditional medicine to treat colds, indigestion, abdominal pain, and cough.

8 Sep 2026

Bacterial Protein Fragment Disrupts Cell Quality Systems Causing Tissue Scarring

A bacterial protein fragment called corisin drives the process of pulmonary fibrosis by infiltrating and disrupting the cell's quality-control system, researchers at the University of Illinois Urbana-Champaign and Mie University in Japan found in a new study.

1 Sep 2026

Novel Chemical Probes Improve Capture of Elusive DNA Repair Proteins

PARylation is a reversible post-translational modification in which PARP enzymes use NAD+ to assemble PAR chains on proteins. These chains can function as signaling scaffolds that recruit proteins involved in DNA repair, chromatin organization, transcription, and stress responses.

1 Sep 2026

Tiny Cell Structures Called Peroxisomes Protect Vital Human Insulin Supply

Researchers at LSU's Pennington Biomedical Research Center have identified a previously underappreciated role for tiny structures inside cells called peroxisomes in protecting insulin and maintaining the health and maturity of insulin-producing pancreatic beta cells.

31 Aug 2026

Research Identifies Essential Energy Sources for Developing Carnivorous Larval Fish

Lipids are essential for fish because they supply energy, support cell structure, and help carry fat-soluble nutrients. This is especially important in carnivorous fish, which use carbohydrates less efficiently than many other animals.

25 Aug 2026

Emerging m6A RNA Biology Explains Brain Vulnerability to Environmental Hazards

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026

Stable RNA Structures Revolutionize Quality of Life in Oncology Care

A new review highlights the growing importance of circular RNAs (circRNAs) in addressing one of the most pressing challenges in modern oncology: treatment-related toxicity.

6 Aug 2026

Systematic Platform Accelerates Identification of Novel Protein Degradation Drug Candidates

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

6 Aug 2026

Scientists Discover How Brain Cells Overcome the Effects of a Disease-Causing Genetic Deletion

Scientists at the Fralin Biomedical Research Institute at VTC have discovered how an experimental therapy can help brain cells overcome the effects of a disease-causing genetic deletion.

29 Jul 2026

Advanced Synthetic Bone Graft Fights Infections and Kills Cancer Cells

Primary bone tumors, such as osteosarcoma, have seen stagnant survival rates over the past four decades.

10 Jul 2026

Winery Waste Becomes Stable Squalane for Greener Cosmetics

Researchers developed an eco-friendly workflow to recover squalene from wine lees using ultrasound-assisted extraction and convert it into more stable squalane using clay-supported palladium catalysts. The upcycled squalane showed improved oxidative stability and enhanced quercetin transport across an artificial membrane, supporting its potential as a sustainable cosmetic excipient.

9 Jul 2026

New Review Outlines Diverse Biological Triggers of Cellular Senescence

A new review was published in Volume 18 of Aging on June 22, 2026, titled "The multifaceted inducers of cellular senescence."

8 Jul 2026

Melatonin Enhances Random Skin Flap Viability by Suppressing Ferroptosis

Random-pattern skin flaps are widely used to repair defects caused by trauma, burns, tumor removal, and other injuries because they can be designed without depending on a single named blood vessel.

29 Jun 2026

Southern Medical University Uncovers Crucial Protein Linked to Lung Fibrosis

A study published recently in Current Molecular Pharmacology has uncovered a key mechanism linking aging to persistent pulmonary fibrosis, identifying the transcriptional regulator fPRDM16 as a potential therapeutic target.

26 Jun 2026

Novel Cyclic Peptides Cross Cell Membranes to Fight Disease

Many diseases are driven by proteins interacting with each other inside cells. But blocking these interactions with drugs is difficult because our typic "small-molecule" drugs often prove to be too small to grip the broad, flat surfaces involved in protein-protein interactions.

1 Jun 2026