Biochemistry

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Chloride ions evoke taste sensation by binding to sweet taste receptors

Humans perceive five basic taste sensations: sweet, umami, bitter, salty, and sour. Specific foods trigger taste recognition of these sensations through the activation of different receptors in our taste buds.

24 Mar 2023

Foods with a high fat and sugar content change our brain, shows study

Chocolate bars, crisps and fries - why can't we just ignore them in the supermarket? Researchers at the Max Planck Institute for Metabolism Research in Cologne, in collaboration with Yale University, have now shown that foods with a high fat and sugar content change our brain: If we regularly eat even small amounts of them, the brain learns to consume precisely these foods in the future.

23 Mar 2023

Pesticide residues in water test kit for sustainable and safe agriculture

Farmers in Thailand still largely use chemical herbicides, especially paraquat and atrazine, to control weeds on their farms. According to research by the Office of Agricultural Economics, in 2019, Thailand imported almost 10 million kilograms of paraquat and close to 3.5 million kilograms of atrazine.

23 Mar 2023

Curcumin could enhance ovarian cancer treatments

A pharmacology researcher at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) has co-authored a new study that makes a strong case for why a golden spice commonly found in curry could enhance ovarian cancer treatments.

23 Mar 2023

Gyros Protein Technologies introduces new PurePep EasyClean services to accelerate development and manufacturing of peptide-based drugs

Gyros Protein Technologies AB today announced the launch of three service offerings to support development and manufacturing of peptide-based drugs.

From Gyros Protein Technologies AB 22 Mar 2023

Amide-to-ester substitutions can enhance the membrane permeability of cyclic hexapeptides

Cyclic peptides often exhibit low membrane permeability which can be significantly improved via amide-to-ester substitutions-;as demonstrated by researchers from Tokyo Institute of Technology.

20 Mar 2023

New antibody "cocktail" may help counter the Lassa virus

The finding, made with the use of the Advanced Photon Source, shows a new way to exploit monoclonal antibodies to subvert the "shield" of the virus, potentially paving the way for new therapies.

20 Mar 2023

Fomepizole may reduce disease severity in the lungs of mice with bacterial pneumonia

Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually.

17 Mar 2023

Potential approach to improve solid tumor T cell therapy

Researchers at the Perelman School of Medicine at the University of Pennsylvania have been working on a preclinical study that focuses on a new strategy that uses a “one-two punch” to assist T cells in attacking solid tumors.

17 Mar 2023

New therapeutic approaches to treat autoimmune diseases using a metabolite

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.

16 Mar 2023

Merging cryo-TEM and tomography methods to reveal 3D morphology of dendrites

Documenting the lithiation process in TEM can provide a deep understanding of the electrode degradation mechanism during battery cycling, which enhances material modification for improved performance. The research was guided by Prof. Dong Su (Institute of Physics, Chinese Academy of Sciences).

15 Mar 2023

Transforming the natural mineral shells of algae into functional perovskites

Perovskites are materials that are increasingly popular for a wide range of applications because of their remarkable electrical, optical, and photonic properties.

14 Mar 2023

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Synthetic biologists at Rice University are embarking on a three-year project to create "genetically encoded antibiotics," strands of RNA that bacteria will readily copy and share that will selectively kill only disease-causing, pathogenic bacteria.

14 Mar 2023

Novel method quantifies the total polysulfide content in fresh vegetables

Sulfur-rich foods, like onions and garlic, have long been recognized to have health-promoting properties. It has been difficult to investigate how food containing sulfur compounds enhances health because the levels—and types—of reactive polysulfides found in various vegetables have not been adequately assessed.

14 Mar 2023

Bile salt hydrolase cocktails may offer a new approach to inhibit C. diff colonization

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

14 Mar 2023

Novel model tracks hippocampal synaptic plasticity to reveal molecular mechanisms

The accumulation of amyloid beta proteins, which encourage synaptic malfunction, causes cognitive decline in Alzheimer’s disease (AD), according to scientific evidence.

10 Mar 2023

Olive oil by-products could have antioxidant benefits

New research has found that a natural by-product of olive oil production could potentially have antioxidant benefits and support exercise.

10 Mar 2023

Scientists shed new light on aging processes in the brain

Scientists from the Trinity Biomedical Sciences Institute (TBSI) have shed new light on aging processes in the brain.

9 Mar 2023

Understanding gas transfer between the atmosphere and ocean can lead to better climate models

The injection of bubbles from waves breaking in turbulent and cold high-latitude regions of the high seas is an underappreciated way in which atmospheric gases are transported into the interior ocean.

8 Mar 2023

Liver-produced hormone protects mice against the harmful effects of intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

Biochemistry

Chloride ions evoke taste sensation by binding to sweet taste receptors

Foods with a high fat and sugar content change our brain, shows study

Pesticide residues in water test kit for sustainable and safe agriculture

Curcumin could enhance ovarian cancer treatments

Gyros Protein Technologies introduces new PurePep EasyClean services to accelerate development and manufacturing of peptide-based drugs

Amide-to-ester substitutions can enhance the membrane permeability of cyclic hexapeptides

New antibody "cocktail" may help counter the Lassa virus

Fomepizole may reduce disease severity in the lungs of mice with bacterial pneumonia

Potential approach to improve solid tumor T cell therapy

New therapeutic approaches to treat autoimmune diseases using a metabolite

Merging cryo-TEM and tomography methods to reveal 3D morphology of dendrites

Transforming the natural mineral shells of algae into functional perovskites

Rice biologists embark on a three-year project to create genetically encoded antibiotics

Novel method quantifies the total polysulfide content in fresh vegetables

Bile salt hydrolase cocktails may offer a new approach to inhibit C. diff colonization

Novel model tracks hippocampal synaptic plasticity to reveal molecular mechanisms

Olive oil by-products could have antioxidant benefits

Scientists shed new light on aging processes in the brain

Understanding gas transfer between the atmosphere and ocean can lead to better climate models

Liver-produced hormone protects mice against the harmful effects of intoxication

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