Cell Biology

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Bioengineers Harness 3D Printing to Create Functional Heart Ventricle

Over the last decade, advances in 3D printing have unlocked new possibilities for bioengineers to build heart tissues and structures.

28 Jul 2023

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients.

28 Jul 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023

A Common Diabetes Drug Helps Prevent Muscle Atrophy and Muscular Fibrosis

You might not think of diabetes when you think of muscle function. But a common diabetes drug that regulates blood sugar can also prevent muscle atrophy and muscular fibrosis-;which can help the elderly bounce back faster from injury or illness.

26 Jul 2023

Researchers Design New Algorithm to Boost Pandemic Preparedness

Immune system researchers have designed a computational tool to boost pandemic preparedness. Scientists can use this new algorithm to compare data from vastly different experiments and better predict how individuals may respond to disease.

26 Jul 2023

Towards Artificial Photosynthesis with Engineering of Protein Crystals in Bacteria

In-cell engineering can be a powerful tool for synthesizing functional protein crystals with promising catalytic properties, show researchers at Tokyo Tech.

26 Jul 2023

New Class of Brain Inhibitory Neurons May Contribute to Autism and Schizophrenia

A University of California, Irvine-led team of researchers working at the Center for Neural Circuit Mapping find links between brain disorders and dysfunction of newly identified inhibitory brain cell types.

26 Jul 2023

Lactate Signaling Found to Be Critical for Neuronal Differentiation

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

25 Jul 2023

'Orphan' Gene may Have Evolved to Give Seahorses Their Unique Brood Pouch

Teleost fish encompass a diverse group, among which seahorses display a unique morphology. The characteristic spines and brood pouch seen in seahorses feature distinctive epithelial cells-;called flame cone cells-;covered by a mucous cap.

25 Jul 2023

Caecilians Pass Microbes to Their Young Through Skin-Feeding

Caecilians are an elusive type of amphibian that primarily live underground and look like a cross between a worm and a snake. One of the few things that is known about caecilians is their unique method for feeding their young.

25 Jul 2023

Dietary Fiber Regulates Gut Microbiota and Improves Epithelial Cell Proliferation

A high-fiber diet is known to have several health benefits. Scientific studies point to protection against such diseases as cancer and diabetes.

25 Jul 2023

Male and Female Rats Show Different Brain Responses to Enriched Environment

Neurobiologists from Immanuel Kant Baltic Federal University found out differences of educability level and processes of formation of spatial memory of adult male and female rats, that live together in large cages and played with toys.

25 Jul 2023

New Protein Found to be Key to Proper Functioning of Acinar Cells

The energy supply in the body has been regulated by the pancreas, located behind the stomach. This mechanism happens by secreting proteins (enzymes) accountable for glucose–the body’s primary fuel–reaching other organs when needed and in the exact amount.

24 Jul 2023