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Ultrasound-Controlled Mechanochemical Systems Offer Precision Drug Activation

Conventional drug delivery often relies on passive diffusion or chemical triggers, which may lead to systemic exposure, toxicity, and decreased therapeutic performance.

20 Nov 2025

Innovative Human Cell Model Shows How Melanoma Thrives in the Brain

Using human cells and cutting-edge technology, the team created a three-dimensional (3D) model that accurately simulates the brain invaded by aggressive cancer.

19 Nov 2025

LEVA Enables Real-Time Tracking of Extracellular Vesicle Communication

In stunning new time-lapse videos, biological nanoparticles scoot and flit across a starry field of glowing dots.

19 Nov 2025

CRISPR Gene Editing Reverses Chemotherapy Resistance in Lung Cancer

In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in lung cancer. The approach restores drug sensitivity and slows tumor growth.

18 Nov 2025

Molecular Test Targets Three Significant Pathogenic Fungi

This innovative assay detects key fungal pathogens with 100% accuracy, addressing urgent diagnostic needs for infections affecting immunocompromised patients.

17 Nov 2025

RNA Imaging Predicts Early Cell Damage with High Sensitivity

NIMS, in collaboration with Nagoya University, Gifu University, and the University of Adelaide, has developed a method for simultaneously imaging DNA and RNA inside cells using harmless infrared to near-infrared light.

14 Nov 2025

Cellarity's AI Model Predicts Drug Induced Liver Injury

Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in Nature Communications, which describes a novel framework for the prediction and characterization of drug-induced liver injury (DILI), along with open-source posting of the model and validation data.

14 Nov 2025

Studying Disease Evolution Through Ancient DNA Analysis

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries. However, because DNA degrades over time, it is difficult for researchers to analyze DNA samples older than 20 years using conventional analytical approaches.

14 Nov 2025

New Tool Studies Kinase Activity During DNA Damage

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases – enzymes that control nearly all cellular processes – turn on and off inside living cells.

14 Nov 2025

New "Ultra-Mild" Method Corrects Cancer DNA Methylation Test Errors

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature Communications. UMBS-seq achieves both accuracy and gentleness, unlocking more reliable cancer biomarker detection.

13 Nov 2025

Bone Regeneration Breakthrough: Next-Gen Nanoparticle-Stem Cell Hybrids Show Promise

A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to significantly improve 3D bone tissue regeneration.

13 Nov 2025

Animal Testing to Be Phased Out Faster as UK Unveils Roadmap for Alternative Methods

Animal testing in science is set to be phased out faster under a new plan to deliver on the government’s manifesto commitment, unveiled by Science Minister Lord Vallance today (Tuesday 11 November).

13 Nov 2025

AlphaSync Brings Continuous Updates to Global Protein Structure Predictions

The shape, or structure, of proteins determines how they work, making it essential for researchers to have access to high-quality structural models.

12 Nov 2025

CellWhisperer Enables Natural Language Exploration of Single-Cell Biology

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.

12 Nov 2025

Study Exposes Critical Security Flaws in Widely Used DNA Sequencing Tech

Portable genetic sequencers used around the world to sequence DNA have critical, previously unreported security vulnerabilities that could reveal or alter genetic information without detection, according to a new study.

11 Nov 2025

New Tool Merges Ex-Vivo and In-Vivo Brain Data for White Matter Research

BraDiPho is an innovative tool for the study of white matter connections in the human brain. A realistic map developed by a group of researchers from the University of Trento, the Provincial Healthcare Service of Trento, Fondazione Bruno Kessler and the Universities of Bordeaux and Sherbrooke.

7 Nov 2025

Decoding DNA’s Spatial Organization With Precision Tools

DNA is more than simply a lengthy string of genetic code; it is a complex three-dimensional structure folded inside each cell. That means that the equipment used to examine DNA must be as sophisticated, capable of reading not just the code itself but also its spatial arrangement.

7 Nov 2025

Using AI and "Protein Language" Models to Speed Monoclonal Antibody Design

Artificial intelligence (AI) and "protein language" models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study led by researchers at Vanderbilt University Medical Center.

6 Nov 2025

3D Ultrasound That Sees Entire Organ Blood Flow in Real Time

This study presents a multi-lens ultrasound system that offers tenfold higher resolution for whole-organ imaging, improving microvascular network visualization.

6 Nov 2025

Weill Cornell Scientists Develop Safe and Precise Tool to Control Gene Activity

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such "gene-switch" tools allow scientists to "turn on" or "turn off" a target gene to study how it works, model diseases and design new therapies.

4 Nov 2025