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Molecular Simulations and AI Reveal Rapid Activation of Catch-Bonds Under Force

Imagine tugging on a Chinese finger trap. The harder you pull, the tighter it grips. This counterintuitive behavior also exists in biology.

13 Sep 2025

Engineered Base Editor Corrects ACTA2 Mutation in Rare Childhood Disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

13 Sep 2025

Adaptive Microfluidic Channel Enhances Impedance Flow Cytometry Sensitivity

Many advances in medicine and drug development were possible owing to flow cytometry, a single-cell analysis technique that analyzes cells using the emitted fluorescence of their chemical tags while passing through a laser beam.

13 Sep 2025

New Genomic Analysis Platform Launched for Tracking for Zoonotic Pathogens

Zoonotic pathogens, capable of crossing between animals and humans, pose escalating threats due to antimicrobial resistance, genetic diversification, and complex transmission patterns.

11 Sep 2025

PhoBITs Enable Unprecedented Control of Cellular Pathways with Blue Light

Imagine being able to flip a light switch to control disease pathways inside a living cell. A team of visionary researchers at the Texas A&M University Health Science Center (Texas A&M Health) is making this dream a reality with their groundbreaking genetic tools known as photo-inducible binary interaction tools, or PhoBITs.

10 Sep 2025

Predicting Protein Metal Binding with New Artificial Intelligence Model

Biologists and computational scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory recently refined two artificial intelligence (AI) programs originally built by Meta, the company that owns Facebook, to predict protein shapes.

10 Sep 2025

Researchers Develop New Technique to Detect Causality in Neural Spike Trains

Understanding the brain's functional architecture is a fundamental challenge in neuroscience. The connections between neurons ultimately dictate how information is processed, transmitted, stored, and retrieved, thus forming the basis of our cognitive functions.

10 Sep 2025

Scientists Engineer E. Coli To Produce Plastic-Building Chemical

This study reveals a novel pathway in E. coli for synthesizing 2,5-pyridinedicarboxylate from glucose, offering a sustainable alternative to fossil fuels.

10 Sep 2025

spVelo: A New Method for Integrating Spatial and Temporal Data in RNA Velocity Analysis

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it will be and its function.

8 Sep 2025

AI Tool for Designing Antibiotics from Scratch

In a recent Cell Biomaterials study, University of Pennsylvania researchers offer AMP-Diffusion, a generative AI tool for creating tens of thousands of novel antimicrobial peptides (AMPs) — short strings of amino acids that serve as the building blocks of proteins — with bacteria-killing capability.

3 Sep 2025

Human-Derived 3D Skin Model May Replace Animals In Wound Studies

Engineered 3D skin model successfully simulates early wound healing, offering insights into inflammatory responses and potential therapeutic applications.

3 Sep 2025

DNA-Wrapped Nanoparticles Enhance Efficiency of Gene Editing Tools

With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine.

2 Sep 2025

GEMORNA Platform Generates Novel mRNA Sequences With Superior Drug Properties

Raina Biosciences Inc., ("Raina"), an mRNA technology and therapeutics company, today announced the publication of data from its generative AI platform in Science.

28 Aug 2025

Ultrack Enables Fast and Accurate Cell Tracking in 3D Embryo Imaging

With today's advanced microscopes, scientists can capture videos of entire embryos developing in real time.

27 Aug 2025

New Computational Tool Enhances Cancer Tissue Analysis for Personalized Treatment

Scientists at the Icahn School of Medicine at Mount Sinai have developed a powerful new computational tool that could transform how cancer tissues are analyzed and help pave the way for more personalized treatments.

27 Aug 2025

Atomic Force Microscopy and AI Transform Understanding of Tangled DNA

At school, it's often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.

22 Aug 2025

Mitsui, QSimulate, and Quantinuum Launch “QIDO”: A Quantum-Integrated Chemistry Platform Targeting Faster Drug and Materials Discovery

Mitsui & Co., Ltd. (“Mitsui”), QSimulate, and Quantinuum today announced the launch of a new quantum-integrated chemistry platform, QIDO (Quantum-Integrated Discovery Orchestrator).

From Quantinuum Ltd 22 Aug 2025

Machine Learning Model Accounts for Biological Variability in Culture Media Design

Cell culture is a foundational technology widely used across fields such as pharmaceutical production, regenerative medicine, food science, and materials engineering. A critical component of successful cell culture is the culture medium-a solution containing essential nutrients that support cell growth.

21 Aug 2025

New Tool Offers Insight Into When Genes Turn On and Off in the Brain

A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on and off over time during brain development - a finding that may one day help doctors identify the optimal window to deploy gene therapy treatments.

20 Aug 2025