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Microfluidics Paves the Way for More Efficient Neural Stem Cell Generation

Swedish researchers have enhanced a method for transforming ordinary skin cells into neural stem cells, a development they believe narrows the accessibility gap for personalized cell-based therapies for Alzheimer's and Parkinson's diseases.

25 Apr 2024

Small RNA-Binding Protein Promotes Prime Editing Efficiency

Through years of engineering gene-editing systems, researchers have developed a suite of tools that enable the modification of genomes in living cells, akin to 'genome surgery'.

23 Apr 2024

OrthoID Method Revolutionizes Protein Identification in Organelle Communication

A collaboration between POSTECH, Daegu Catholic University School of Medicine, and Seoul National University unveils a novel strategy for identifying key proteins in organelle communication.

15 Apr 2024

Leveraging the Materiobiology Approach to Design Biomaterials for Aged Bone Repair

In the elderly, a multitude of factors contribute to diminished bone regeneration capabilities, including a reduction in the self-renewal and differentiation abilities of mesenchymal stem cells, an excessive accumulation of inflammatory signals, compromised blood vessel regeneration capacity, an imbalance between bone anabolism and catabolism, and inadequate bone innervation.

13 Apr 2024

AI Predicts Mutations for Improved Protein Function

To design proteins with beneficial functions, researchers typically start with a natural protein possessing a desirable function, such as emitting fluorescent light.

5 Apr 2024

New Tool Predicts How Proteins Interact with RNA Structures

Scientists at the Italian Institute of Technology and Aarhus University have figured out how specific proteins can bind to G-quadruplexes, which are unique RNA structures.

4 Apr 2024

TAM-Sense Offers Painless Imaging of Tumor Inflammation

The National Institutes of Health (NIH) has awarded two new grants totaling $6.7 million to researchers at the University of California San Diego School of Medicine.

2 Apr 2024

Groundbreaking AI Framework Revolutionizes Drug Discovery

A transformative study published in Health Data Science, a Science Partner Journal, introduces a groundbreaking end-to-end deep learning framework, known as Knowledge-Empowered Drug Discovery, aimed at revolutionizing the field of drug discovery.

1 Apr 2024

Scientists Create Lifelike Human Ear Replica with 3D Printing

Using state-of-the-art tissue engineering techniques and a 3D printer, researchers at Weill Cornell Medicine and Cornell Engineering have assembled a replica of an adult human ear that looks and feels natural.

1 Apr 2024

Autofluorescence Reveals Clues to Stem Cell Dormancy

With the help of a tool created at the University of Wisconsin–Madison, researchers can better study the various states of stem cells in the nervous system by utilizing the light naturally emitted by biological specimens.

28 Mar 2024

GPT-4 Streamlines Cell Type Identification in Single-Cell RNA Sequencing

A new study by Columbia University’s Mailman School of Public Health shows that GPT-4, a large language model, can accurately identify cell types in single-cell RNA sequencing data.

26 Mar 2024

Artificial Glycocalyx-Based Method Detects Intact Bacteria

Each year, bacterial infections claim several million lives worldwide. That is why detecting harmful microorganisms is crucial – not only in the diagnosis of diseases but also, for example, in food production.

26 Mar 2024

Novel Microfluidic Device for Rapid Plant Stress Diagnosis via miRNA Detection

In natural environments, plants encounter biotic and abiotic stresses that can significantly affect their productivity and health.

25 Mar 2024

Groundbreaking Physics Study Offers Insights Into Self-Organization of Biological Particles

Erin McCarthy '23, physics summa cum laude, is a rarity among young scientists. As an undergraduate researcher in Syracuse University's College of Arts & Sciences' Department of Physics, she guided a study that appeared in March 2024 in Physical Review Letters. It is the most-cited physics letters journal and the eighth-most cited journal in science overall.

25 Mar 2024

Integrating Computational Intelligence for Accurate 3D Modeling of Maize Canopies

Understanding the structure of crop canopies is essential for optimizing crop production as it significantly influences resource utilization efficiency, yield and stress resistance.

22 Mar 2024

Bioinformatics Tool Recognizes Chromosome Changes in Cancer Cells

A group from IRB Barcelona and the University of Barcelona has created a novel bioinformatics instrument to recognize the chromosomal changes characteristic of cancerous cells.

22 Mar 2024

AI Tool Discovers Hidden Diversity in Major Crops

Researchers have created a new computational tool that quickly and effectively exposes genetic variety inside DNA databases of different plant species, which is a significant advancement for agricultural science.

21 Mar 2024

Machine Learning Accelerates Personalized T Cell Therapy Development for Cancer Patients

Making a personalized T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center and the University Medical Center Mannheim have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.

18 Mar 2024

Method Seeks to Eliminate the Need for Frozen mRNA Vaccines

CEPI has provided funding to a public research university in Belgium to investigate whether a novel vaccine stabilization method could eliminate the need for mRNA vaccines to be stored in frozen storage and enable a quick and expanded response to future outbreaks in as little as 100 days.

14 Mar 2024

New CRISPR Method Allows Comprehensive Screening of Cancer Mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

13 Mar 2024