Drug Discovery & Pharmaceuticals

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Multiple micronutrient supplements included in the WHO Model List of Essential Medicines

The New York Academy of Sciences today announced that multiple micronutrient supplements (MMS) have now been included in the World Health Organization's (WHO) Model List of Essential Medicines (known as EML), as an antenatal supplement for pregnant women.

6 Oct 2021

Common drug to treat cancer reverses Alzheimer’s symptoms in mice

A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer's disease, new UBC research has found.

6 Oct 2021

Ketone supplement may be a new therapeutic strategy for enhancing brain health in adults with obesity

New research published in The Journal of Physiology has shown that ketone supplements may be a novel therapeutic strategy for protecting and improving brain health in people with obesity.

5 Oct 2021

New datasets published to better train ML models for drug discovery

Polymorphs are molecules that have different molecular packing arrangements despite identical chemical compositions. In a recent paper, researchers at GlaxoSmithKline (GSK) and the Cambridge Crystallographic Data Centre (CCDC) combined their proprietary (GSK) and published (CCDC) datasets to better train machine learning (ML) models to predict stable polymorphs to use in new drug candidates.

4 Oct 2021

Delta opioid receptor agonists modulate immune responses to ameliorate colonic inflammation

Opioids are a class of substances that control sensations such as pain and emotions in animals. While plant-derived opioid narcotics such as morphine are the most well-recognized, other opioid molecules like endorphins can also be synthesized by the body or artificially developed in laboratories.

From Tokyo University of Science 1 Oct 2021

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Researchers elucidate why certain drugs, in clinical trials, for treating a kind of acute myeloid leukemia often fail and revealed a means to restore their efficacy.

1 Oct 2021

The new FlowCam® LO improves particle characterization in drug development

Yokogawa Fluid Imaging Technologies announces the release of the FlowCam® LO, the first and only light obscuration instrument with imaging capabilities.

From Yokogawa Fluid Imaging Technologies, Inc. 29 Sep 2021

Llamas' nanobodies could provide a new frontline treatment against Covid-19

A unique type of tiny antibody produced by llamas could provide a new frontline treatment against Covid-19 that can be taken by patients as a simple nasal spray.

23 Sep 2021

Rice researcher secures $1.9 million NIH grant to improve time-release drugs

Time-released drugs are about to get a geometry lesson, thanks to bioengineers at Rice University.

22 Sep 2021

UC Riverside scientists aim to turn edible plants into mRNA vaccine factories

The future of vaccines may look more like eating a salad than getting a shot in the arm. UC Riverside scientists are studying whether they can turn edible plants like lettuce into mRNA vaccine factories.

17 Sep 2021

New treatment developed from plant virus could keep metastatic cancers at bay

Using a virus that grows in black-eyed pea plants, nanoengineers at the University of California San Diego developed a new treatment that could keep metastatic cancers at bay from the lungs.

From UC San Diego 15 Sep 2021

New drug delivery strategy could make it easier for patients to take their medications

In recent years, scientists have developed monoclonal antibodies -; proteins that mimic the body's own immune defenses -; that can combat a variety of diseases, including some cancers and autoimmune disorders such as Crohn's disease.

31 Aug 2021

Study proposes a novel approach for developing safer analgesics

Opioids are potent painkillers; however, their use is hampered as patients become tolerant to them, necessitating more and more doses.

From The University of California, Davis 31 Aug 2021

Small synthetic molecules could one day cure or prevent COVID-19, herpes

In addition to antibodies and white blood cells, the immune system deploys peptides to fight viruses and other pathogens.

24 Aug 2021

Researchers identify potent antibody that protects against a wide range of viral variants

The virus that causes COVID-19 today is not the same as the one that first sickened people way back in December 2019.

23 Aug 2021

Understanding computational fluid dynamics can inform more effective design of drug delivery devices

Increased air pollution in recent years has not only contributed to deteriorating environmental conditions in cities across the globe.

12 Aug 2021

Researchers create new drug database to facilitate repurposing of drugs

Scientists developed a new open-access database with information on drug candidates and the process of metabolization of the drugs by the body.

5 Aug 2021

Study highlights novel approach for designing anti-viral drugs

Scientists are exploring a novel screening approach that concentrates on the recognition of virus-specific morphological changes in virus-infected cells.

4 Aug 2021

Researchers develop a cost-effective and versatile approach for drug synthesis

Different factors influence the cost-effectiveness of drug synthesis, the amount of waste generated being one of those.

29 Jul 2021

Researchers enhance antibacterial activity of hydrogen peroxide using copper-containing polymers

The discovery of antibiotics is a significant milestone, which saved many lives.

From Tokyo University of Science 29 Jul 2021