Genomics

RSS

Genes2Genes Unlocks New Potential for Detecting Gene Expression Changes

Genes2Genes an accurately infer alignments in simulated and real datasets of single-cell trajectories and capture sequential mismatches and matches in individual genes.

4 Oct 2024

Structural Discovery of Fanzor Proteins Offers New Directions in Genome Engineering

A revolution in biomedicine is currently underway, driven by the application of genome engineering tools such as the prokaryotic CRISPR-Cas9.

3 Oct 2024

New Insights into the Epigenetic Hallmarks of Cancer

Cancer mortality has just surpassed cardiovascular disease for the first time ever and one in two men, and one in three women, will be diagnosed with some form of the disease in the US, according to the NIH.

3 Oct 2024

Unlocking the Mysteries of Repeat Expansion in Genetics

Research led by scientists at Queen Mary University of London is heralding in a new era for genetic sequencing and testing.

3 Oct 2024

New Insights into U1 Snrnp Functions in Plant Splicing Mechanisms Using Arabidopsis

U1 snRNP interactions in Arabidopsis highlight its dual role in splicing and mRNA regulation, essential for maintaining transcript integrity and growth.

2 Oct 2024

Study Reveals Gene Linked to Cold Resistance in Hibernating Mammals

A gene that limits cellular damage could be the key to surviving prolonged cold exposure.

1 Oct 2024

New Tool START Enables Precision Mapping of Neuronal Connectivity

Scientists at the Salk Institute are unveiling a new brain-mapping neurotechnology called Single Transcriptome Assisted Rabies Tracing (START). The cutting-edge tool combines two advanced technologies-;monosynaptic rabies virus tracing and single-cell transcriptomics-;to map the brain's intricate neuronal connections with unparalleled precision.

1 Oct 2024

Bipolar Disorder and Epilepsy Share Genetic Roots

A team of researchers from the Chinese Academy of Sciences has uncovered compelling evidence of a genetic link between bipolar disorder type I (BD-I) and epilepsy, potentially revolutionizing our understanding of these complex neuropsychiatric conditions.

1 Oct 2024

Two Alzheimer’s Genetic Risk Factors Trigger Harmful Inflammation in Females

Weill Cornell Medicine investigators have found that two genetic variants that confer high risk of Alzheimer's disease (AD) together trigger a harmful inflammatory response in the brain's immune cells, particularly in females, in a preclinical model.

1 Oct 2024

A Novel Genetic Inference Method for Detecting Rare Disease Variants

Undiagnosed cases of Long QT syndrome have been found, thanks to an inventive examination of shared genomic sequences, which is a sign of distant “relatedness” and can cause irregular heart rhythms, fainting, and sudden cardiac death.

30 Sep 2024

Hydrogen Sulfide Plays a Crucial Role in Bacterial Survival

Two crucial biological processes that support the growth of bacteria, particularly pathogenic bacteria like Escherichia coli, are antibiotic resistance and the oxidative stress response.

30 Sep 2024

Huntington's Disease Protein Disrupts DNA Repair

Researchers at McMaster University have found that the mutated protein in Huntington's disease patients disrupts DNA repair as it should, which affects the capacity of brain cells to regenerate.

30 Sep 2024

Motor And Extracellular Matrix Proteins Play A Critical Role In Cleft Palate Formation

The study reveals 44 differentially expressed proteins in cleft palate models, shedding light on molecular mechanisms and potential prenatal diagnostic markers.

30 Sep 2024

Genomic Insights Reveal Path Forward for Inbred Red Fox Populations

A rescue effort can take many forms – a life raft, a firehose, an airlift. For animals whose populations are in decline from inbreeding, genetics itself can be a lifesaver.

27 Sep 2024

Gut Bacteria Influence Hormonal Balance and Hypopituitarism Symptoms in Mice

Researchers at the Francis Crick Institute have shown that the balance of bacteria in the gut can influence symptoms of hypopituitarism in mice.

27 Sep 2024

Study: Vaping Alters DNA in Ways Similar to Smoking

Young adults who vape show chemical changes in their DNA similar to those found in young adults who smoke -; changes known to be linked to the development of cancer -; according to a new study just published in the American Journal of Respiratory Cell and Molecular Biology.

26 Sep 2024

New AI Tool Revolutionizes Prediction of Rare Genetic Variant Effects

Whether we are predisposed to particular diseases depends to a large extent on the countless variants in our genome.

26 Sep 2024

Study Reveals Simplified Rules for Predicting Protein Behavior

In a study published today in the journal Nature, researchers from the Centre for Genomic Regulation (CRG) and the Wellcome Sanger Institute have discovered that mutations affect protein stability following remarkably simple rules.

26 Sep 2024

Metagenomic Study Reveals the Most Ancient Dairy Remains Known to Date

The oldest method of producing food with microorganisms in human history is food fermentation. Cheese production and consumption dates back to 7000 before the present (BP) among Mediterranean populations, and milk fermentation, for instance, dates back to 6000–4000 BC in India.

26 Sep 2024

Bacteria Can Recode Their Genetics With a Single Flip

Envision being a single cartwheel away from altering looks. The brown locks will turn platinum blond with just one flip. That is similar to what occurs in certain prokaryotes, or single-celled creatures like bacteria when they go through a process known as inversions.

26 Sep 2024