Genomics

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Global Gene Expression Data Improves Precision in Genetics

The majority of human genetics research has traditionally concentrated on individuals with European ancestry, a long-standing bias that may reduce the precision of scientific predictions for individuals from other populations.

18 Jul 2024

New Model Reveals Interplay Between Circadian Rhythms and Sleep-Wake Cycles in Gene Expression

A mathematical, driven, damped harmonic oscillator model to assess the varying contributions of circadian cues and sleep-wake processes on gene expression and the rhythmic transcriptome.

18 Jul 2024

ENGRAM: Capturing Cellular Histories Through Genomic Recording

Genomes can now be entrusted to store information about a variety of transient biological events inside of living cells, as they happen, like a flight recorder collecting data from an aircraft.

18 Jul 2024

Reawakened Endogenous Retroviruses can Play a Critical Role in Helping Cancer Survive

Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you'll also find flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago.

18 Jul 2024

Fossils in Our Genes: Giant Viruses Leave Mark on Animal Relative

Recent research published in Science Advances uncovers an unexpected twist in the evolutionary history of complex life.

17 Jul 2024

PUMA: A Breakthrough in CRISPR-Cas12 for RNA Biomarker Detection

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

17 Jul 2024

FAM110A's Dual Role: Orchestrating Microtubule-Actin Interactions in Mitosis

An international research collaboration, led by Prof. Dr. Robert Grosse (Centre for Integrative Biological Signalling Studies and Institute of Clinical and Experimental Pharmacology and Toxicology, University of Freiburg), Dr. Libor Macurek (Institute of Molecular Genetics, Czech Academy of Sciences, Prague) and Dr. Zdenek Lansky (Institute of Biotechnology, Czech Academy of Sciences, Prague) has uncovered a new mechanism of the crosstalk between microtubules and actin cytoskeleton during cell division and revealed unique characteristics of the previously unexplored protein FAM110A.

17 Jul 2024

How an obesity gene influences brain function

A complex condition, obesity is brought on by a confluence of factors including behavior, diet, and heredity. Getting enough food to survive and thrive was a challenge for millennia.

16 Jul 2024

Neuregulin 3 Gene Variant Linked to Gabapentin Effectiveness in Chronic Pelvic Pain

Women who carry a particular form of a pain gene are more likely to respond well to a common medication used to treat long-term discomfort, research shows.

16 Jul 2024

All-RNA Gene Writing Method Paves Way for Precise Gene Editing in Human Cells

A novel gene-writing technology based on retrotransposons.

15 Jul 2024

Advancing Equitable and Inclusive DNA Research in Africa: A Vision for the Future The American Journal Of H...

Today, the American Journal of Human Genetics published a perspective piece on the need for an equitable and inclusive future for DNA and ancient DNA (aDNA) research in Africa.

12 Jul 2024

Scientists Discover Fossils of Ancient Chromosomes in the Remains of Woolly Mammoth

A team led by scientists from Baylor College of Medicine, University of Copenhagen, and Centre Nacional d'Anàlisi Genòmica and Centre for Genomic Regulation report discovering fossils of ancient chromosomes in the remains of a woolly mammoth that died 52,000 years ago.

12 Jul 2024

New Gene Editing Technique Outperforms Existing Therapies

Cystic fibrosis, a prevalent genetic disorder, leads to thick mucus accumulation in the lungs and other parts of the body, resulting in breathing difficulties and infections.

11 Jul 2024

New Insights into ILC2 Development Could Lead to Innovative Therapies for Allergic Diseases

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Phage Protein Discovery Holds New Key to Battling Bacteria

An unexpected find has enabled important progress to be made in the battle against harmful bacteria.

11 Jul 2024

UNC-Chapel Hill Study Reveals New Mechanism of Gene Regulation Beyond Histone Modification

University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation according to the paper, "Drosophila melanogaster Set8 and L(3)mbt function in gene expression independently of histone H4 lysine 20 methylation," published in Genes & Development.

11 Jul 2024

Genomics

Global Gene Expression Data Improves Precision in Genetics

New Model Reveals Interplay Between Circadian Rhythms and Sleep-Wake Cycles in Gene Expression

ENGRAM: Capturing Cellular Histories Through Genomic Recording

Reawakened Endogenous Retroviruses can Play a Critical Role in Helping Cancer Survive

Fossils in Our Genes: Giant Viruses Leave Mark on Animal Relative

PUMA: A Breakthrough in CRISPR-Cas12 for RNA Biomarker Detection

FAM110A's Dual Role: Orchestrating Microtubule-Actin Interactions in Mitosis

How an obesity gene influences brain function

Neuregulin 3 Gene Variant Linked to Gabapentin Effectiveness in Chronic Pelvic Pain

All-RNA Gene Writing Method Paves Way for Precise Gene Editing in Human Cells

Advancing Equitable and Inclusive DNA Research in Africa: A Vision for the Future The American Journal Of H...

Scientists Discover Fossils of Ancient Chromosomes in the Remains of Woolly Mammoth

New Gene Editing Technique Outperforms Existing Therapies

New Insights into ILC2 Development Could Lead to Innovative Therapies for Allergic Diseases

Phage Protein Discovery Holds New Key to Battling Bacteria

UNC-Chapel Hill Study Reveals New Mechanism of Gene Regulation Beyond Histone Modification

Retron-Based Tool Enables Multi-Site DNA Editing

New Pipeline Studies Viruses in Humans and Coral Reefs

Harnessing Proteomics For Food Safety: Allergen Profiling and Food Authenticity Verification

A New Tool to Unravel the Mysteries of Metabolic Genes

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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