Genomics

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Cornell scientists explore how human genetics impacts gut microbiome function

New research from Cornell scientists is exploring how human genetics impacts functions of the gut microbiome, and is expanding awareness of the role human genetics plays in shaping the microbiome.

22 Apr 2022

Study shows how whole genome sequencing test reveals details about cancer growth

Professor Serena Nik-Zainal of Cambridge University Hospitals (CUH) and the University of Cambridge headed a group of scientists that analyzed the whole genetic make-up or whole-genome sequencing (WGS) of over 12,000 NHS cancer patients in the largest research of its type.

22 Apr 2022

Study highlights an effective technique to overcome the rice yield constraint

Tradeoffs between diverse agronomic traits constrain crop breeding to a great extent. Because gene pleiotropy causes many of these tradeoffs, lowering gene pleiotropy may make it simpler to overcome tradeoffs in plant breeding.

22 Apr 2022

Extra copies of DNA explain insensitivity to chemotherapy in germ cell cancer

Extra copies of a piece of DNA partly explain insensitivity to chemotherapy in germ cell cancer, a new study shows.

21 Apr 2022

Alzheimer’s patients tend to have differed and increased genetic changes, says study

Errors present in DNA can get accumulated inside brain cells as one is aging. However, in patients with Alzheimer’s disease, these errors called somatic mutations may increase at a quicker rate.

21 Apr 2022

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

The loss of functional neurons in the brain is a characteristic of Alzheimer’s disease. What, on the other hand, is the source of this loss?

21 Apr 2022

Genomics provides a deeper understanding of the cause of hydrocephalus

The cerebral ventricles—four linked cavities of the brain that are packed with cerebrospinal fluid—become enlarged in hydrocephalus, or “water on the brain;” however, the cause is unknown in many instances.

20 Apr 2022

Zbtb38 removal results in early embryonic death

DNA methylation is a critical epigenetic alteration for mammalian development.

20 Apr 2022

Study identifies new targets for treating sorafenib-resistant hepatocellular carcinoma using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

From University of Pittsburgh 20 Apr 2022

Deeper understanding of genomics support researchers discover new perceptions

In genomic studies, researchers look at a population’s DNA to figure out how genetics affects health and disease.

20 Apr 2022

Epigenetic regulator helps determine lung cancer patients and their resistance to drugs

Doctors commonly use tyrosine kinase inhibitors, particularly epidermal growth factor receptor inhibitors, to cure patients with non-small cell lung cancer, a common and typically deadly kind of cancer that accounts for 80% to 85% of lung cancers.

20 Apr 2022

Researchers develop epigenetic methods for effective cancer treatments

If genetics is concerned with gene sequencing, epigenetics is concerned with how genes are employed (or not) by a cell.

19 Apr 2022

Researchers use CRISPR gene editing tool to analyze globin gene switching

CRISPR gene editing—a form of “molecular scissors”—was used by UNSW researchers to investigate how deletions in one section of the genome might impact the expression of surrounding genes.

From The University of New South Wales (UNSW) 19 Apr 2022

AMN1: New gene target for antifungal therapy against cluster-forming pathogenic fungus

A recent study indicates that regulating and deleting a particular gene (AMN1) in yeast might lay the groundwork for a novel method of addressing drug resistance in microbial infections and cancer.

18 Apr 2022

From Test Tube to Cell; Creating Biological Computers from RNA

In this interview, we speak to Dr. Sam Schaffter about his latest research that looked at creating biological computers using RNA and their role within research.

From National Institute of Standards and Technology (NIST) 18 Apr 2022

Researchers provide a roadmap to get genetic ancestry right for science and society

In a Policy Forum, Anna Lewis and colleagues argue that, for researchers and others who want to invoke genetic ancestry, there is a scientific and ethical imperative to move away from continental ancestry categories and to instead embrace a view of genetic ancestry that reflects continuous variation and historical depth.

15 Apr 2022

Genomics

Cornell scientists explore how human genetics impacts gut microbiome function

Study shows how whole genome sequencing test reveals details about cancer growth

Study highlights an effective technique to overcome the rice yield constraint

Extra copies of DNA explain insensitivity to chemotherapy in germ cell cancer

Alzheimer’s patients tend to have differed and increased genetic changes, says study

Researchers analyze single-cell DNA sequencing for having a significant role in Alzheimer’s disease

Genomics provides a deeper understanding of the cause of hydrocephalus

Zbtb38 removal results in early embryonic death

Study identifies new targets for treating sorafenib-resistant hepatocellular carcinoma using CRISPR-Cas9 screening

Study provides a deeper understanding of how gene mutations contribute to breast cancer progression

Deeper understanding of genomics support researchers discover new perceptions

Epigenetic regulator helps determine lung cancer patients and their resistance to drugs

Researchers develop epigenetic methods for effective cancer treatments

Researchers use CRISPR gene editing tool to analyze globin gene switching

AMN1: New gene target for antifungal therapy against cluster-forming pathogenic fungus

From Test Tube to Cell; Creating Biological Computers from RNA

Researchers provide a roadmap to get genetic ancestry right for science and society

A new Yale study identifies a deeper understanding of cancer-relevant genes

Bioprinting bone along with two growth factor encoding genes improves bone repair

Researchers discover a mechanism by which the protein DELE1 detects organelle stress

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Latest in Genomics