Genomics

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Sampling zoo air could help collect enough DNA to identify the animals nearby

The air in a zoo is full of smells, from the fish used for feed to the manure from the grazing herbivores, but now we know it is also full of DNA from the animals living there.

7 Jan 2022

Experts develop Immuno-CRISPR assay to detect kidney transplant complications

Doctors monitor kidney transplant recipients for signs of rejection in several ways, including biopsy.

7 Jan 2022

Research shows how bacteria silence potentially deadly genes

Humans are all made of collections of cells, where each cell contains instructions in the DNA to become another cell.

7 Jan 2022

Experts introduce new gene therapy approach for muscle weakness

Experts at Children’s National Hospital have created a new pre-clinical gene therapy for the rare condition limb-girdle muscular dystrophy (LGMD) 2B.

7 Jan 2022

Novel delivery system for genome editing in vascular endothelial cells developed

The laboratory of Youyang Zhao developed a novel nanoparticle to deliver genome editing technology, such as CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

7 Jan 2022

Researchers use genomics to dig deeper into lychee’s history

Lychees, prickly on the exterior but sweet inside are loved for their iconic pink shells and pearly, fragrance.

7 Jan 2022

Research analyzes horizontal gene transfer between viruses and eukaryotes

The level at which viruses can pick up genes from their hosts to hone their infection process is illustrated by the first analysis of viral horizontal gene transfer.

7 Jan 2022

Researchers fine-tune an additional system for more efficient gene editing

Over the past decade, the CRISPR genome-editing system has revolutionized molecular biology, giving scientists the ability to alter genes inside living cells for research or medical applications. Now, researchers at Gladstone Institutes have fine-tuned an additional system for more efficient gene editing, using molecules called retrons.

6 Jan 2022

Genetic material found in blood samples can detect women at risk of pre-eclampsia

A study of pregnant women's blood RNA has found specific molecular profiles that identify women at risk of pre-eclampsia. These insights can identify complications before a woman experiences symptoms.

6 Jan 2022

A folic acid-like drug changes a DNA process within brain tumors

A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.

From Vanderbilt University 6 Jan 2022

Olfactory receptor gene may drive breast cancer metastasis to the brain

An olfactory receptor gene that aids in the sense of smell may also play a role in the metastasis of breast cancer to the brain, bones and lung, researchers from Massachusetts General Hospital have found.

4 Jan 2022

Study reveals a tug-of-war between genes inherited from the father and the mother

Cambridge scientists have identified a key signal that the fetus uses to control its supply of nutrients from the placenta, revealing a tug-of-war between genes inherited from the father and from the mother. The study, carried out in mice, could help explain why some babies grow poorly in the womb.

28 Dec 2021

Genes key to microbial colonization of plant roots discovered

Some microbes can form thin films called biofilms. These biofilms give them an advantage over other microbes by protecting them from stresses such as a lack of nutrients or the presence of harmful substances in the environment.

24 Dec 2021

Scientists discover hotspots in the 'dark genome' associated with schizophrenia and bipolar disorder

Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder.

24 Dec 2021

A genetic variation makes sugar healthy for some Greenlanders

A genetic variation among some Greenlanders makes sugar healthy – significantly more than for most people.

23 Dec 2021

Researchers identify genes responsible for “spinach teeth”

People are generally familiar with “spinach teeth,” the harmless but gritty-chalky mouthfeel triggered because of a vegetable.

23 Dec 2021

Experts carry out the first major genetic study into cortical folding patterns

The brain’s surface, the cortex, is folded into an intricate pattern of grooves (sulci) and bumps (gyri). Individual differences in this pattern are associated with cognitive performance and brain disorders, however very little is known on how the “bumpiness and grooviness” of the cortex is determined.

23 Dec 2021