Molecular & Structural Biology

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Two plant stem cell proteins control the division of cells and their response to stress

Researchers have discovered that two plant stem cell proteins physically interact and regulate each other to prevent cellular division.

From University of Barcelona 7 Jul 2021

Making memories necessitates a lot of DNA breakage

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations--more than previously realized, according to a new study--to provide quick access to genetic instructions for the mechanisms of memory storage.

7 Jul 2021

Researchers uncover cellular mechanisms by which the silencing therapies act in cells

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

CRISPR-Cas9 system could help perform very effective target gene silencing

CRISPR-Cas9's extraordinary ability to modify specific areas of DNA has made it a favorite among gene-editing tools for researchers.

6 Jul 2021

New study maps the evolutionary history and interrelationships of protein domains

Since the start of the COVID-19 epidemic, proteins have been stealthily taking over human lives.

2 Jul 2021

Study reveals how plants manage to live alongside each other at the time of stress

Scientists have figured out how plants can coexist in dark, shady environments.

1 Jul 2021

Deep machine learning adds to the knowledge of one million molecules’ bioactivity

The Structural Bioinformatics and Network Biology team at IRB Barcelona has developed a tool that predicts the biological activity of chemical compounds.

30 Jun 2021

New 3Cs multiplex approach enables the study of the effect of genetic changes

Dr Manual Kaulich’s team at Goethe University has developed a new 3Cs multiplex approach that permits the effect of genetic alterations in any two genes to be investigated simultaneously in cell cultures.

25 Jun 2021

Prevalent protein in the blood plays a vital role in human fertilization, infection resistance

Albumin activates a proton channel which allows sperm to penetrate and fertilize an egg and white blood cells to secrete large amounts of inflammatory mediators.

23 Jun 2021

Novel protein interactions aid in the recovery process of brain damage

Patients suffering from brain damage largely depend on rehabilitation therapy for recovery, because no other effective treatment options are available.

21 Jun 2021

Polyamines with known functionalities can treat age-related disorders

According to a new scientific study, recently published in the Nature Catalysis journal, baker's yeast can be engineered and improved to create polyamines and polyamine analogs to address major problems in both the health and agriculture sectors.

21 Jun 2021

Protein known to mediate cell death plays a key role in maturation and release of interleukin-1α

Interluekin-1α (IL-1α) is an important part of the immune response, but until now it has been unclear how this molecule is processed from its precursor, pro-IL-1α, and exits the cell during inflammasome activation.

21 Jun 2021

Researchers systematically analyze alternative splicing in the family of glutamate receptors

Alternative splicing can lead to the formation of numerous protein variants. For the first time, alternative splicing has now been systematically analysed for the family of glutamate receptors.

17 Jun 2021

Study reveals the key role of motor proteins in mitotic spindle elongation

Proper chromosome segregation into two future daughter cells requires the mitotic spindle to elongate in anaphase. However, although some candidate proteins are implicated in this process, the molecular mechanism that drives spindle elongation in human cells has been unknown, until now!

16 Jun 2021

New method reveals high-resolution structure of biomolecules

A new study integrates molecular dynamics simulations and experimental data to inspect biomolecules in their natural environment.

16 Jun 2021

Single mutation leads to rare genetic muscle disease

The origin of rare, severe muscle disease has been uncovered by an international team of researchers headed by the University of Bonn (Germany).

16 Jun 2021

Human cells can convert RNA sequences into DNA

Cells include machinery that replicates DNA into a new set, and this, in turn, develops into a newly formed cell.

15 Jun 2021

Naked mole rats' unique DNA repair mechanism helps prevent cancers, dementia

Scientists say naked mole rats - a rodent native to West Africa - may hold the key to new treatments for degenerative diseases such as cancer and dementia.

11 Jun 2021

New understanding of the molecular basis behind continuous stem cell activity in plants

An inter-university research group has succeeded in constructing the gene expression network behind the vascular development process in plants. They achieved this by performing bioinformatics analysis using the 'VISUAL' tissue culture platform, which generates vascular stem cells from leaf cells.

11 Jun 2021

New “phase separation” protects against premature aging, neurological disorders

According to a new study, a mechanism through which an RNA, called NORAD, drives the Pumilio protein to create liquid droplets in cells—similar to oil in water—appears to closely control the activity of this protein.

11 Jun 2021

Molecular & Structural Biology

Two plant stem cell proteins control the division of cells and their response to stress

Making memories necessitates a lot of DNA breakage

Researchers uncover cellular mechanisms by which the silencing therapies act in cells

CRISPR-Cas9 system could help perform very effective target gene silencing

New study maps the evolutionary history and interrelationships of protein domains

Study reveals how plants manage to live alongside each other at the time of stress

Deep machine learning adds to the knowledge of one million molecules’ bioactivity

New 3Cs multiplex approach enables the study of the effect of genetic changes

Prevalent protein in the blood plays a vital role in human fertilization, infection resistance

Novel protein interactions aid in the recovery process of brain damage

Polyamines with known functionalities can treat age-related disorders

Protein known to mediate cell death plays a key role in maturation and release of interleukin-1α

Researchers systematically analyze alternative splicing in the family of glutamate receptors

Study reveals the key role of motor proteins in mitotic spindle elongation

New method reveals high-resolution structure of biomolecules

Single mutation leads to rare genetic muscle disease

Human cells can convert RNA sequences into DNA

Naked mole rats' unique DNA repair mechanism helps prevent cancers, dementia

New understanding of the molecular basis behind continuous stem cell activity in plants

New “phase separation” protects against premature aging, neurological disorders

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