Molecular & Structural Biology

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Study sheds light on the function of ribosome binding sites

Genome sequencing of plants, bacteria, and even human beings has turned out to be a standard process, but despite this fact, the genome continues to raise several unanswered questions.

28 Aug 2020

Study shows how two proteins interact to produce functioning barrier at tricellular contacts

Organs in animals and in humans have one thing in common: they are bounded by so-called epithelial cells. These, along with the muscle, connective, and nervous tissues, belong to the basic types of tissue.

28 Aug 2020

Study describes anatomical embodiment of color sensations in the brain

A recent study published in Neuron described in greater detail than ever before the anatomical embodiment of color sensations in the cerebral cortex, linking brain structure to perceptual function.

28 Aug 2020

DNA repair enzymes offer potential drug targets for personalized cancer therapies

Chemical lesions in the genetic material DNA can have catastrophic consequences for cells, and even for the organism concerned.

28 Aug 2020

Largely ignored 'housekeeping' gene plays unexpected role in neurological diseases

Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.

27 Aug 2020

Protein structural study may lead to more improved research on disease development

Researchers had identified an actin cytoskeketal nucleator, called Arp2/3 complex, more than 20 years ago.

26 Aug 2020

Chemical crosslinking data helps study protein dynamics

The mechanism for protein function can be unraveled by defining protein dynamics.

26 Aug 2020

Scientists document communication pathways in SARS-CoV-2 infected human cells

In the transmission of signals within the cell which, for example, stimulate cell growth or trigger metabolic processes, phosphate groups play an important biochemical role.

26 Aug 2020

Study uncovers how the immune system generates effective antibodies

An in-depth Garvan study of how the immune system generates effective antibodies provides new insights for vaccine design.

25 Aug 2020

New approach could slow colon cancer metastasis

When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths.

25 Aug 2020

Researchers discover antibodies that may provide effective immunity against SARS-CoV-2

A new study by researchers at MassBiologics of UMass Medical School published in Nature Communications suggests that COVID specific IgA monoclonal antibodies may provide effective immunity in the respiratory system against the novel coronavirus - a potentially critical feature of an effective vaccine.

25 Aug 2020

STING protein activates a pathway that kills tumor-fighting immune cells

The immune protein STING has long been noted for helping protect against viruses and tumors by signaling a well-known immune molecule. Now, UT Southwestern scientists have revealed that STING also activates a separate pathway, one that directly kills tumor-fighting immune cells.

25 Aug 2020

Fault in RNA quality control system causes haywire production of toxic proteins

Osaka, Japan - Researchers at Osaka University have identified a fault in the RNA quality control system of cells that leads to the haywire production of toxic proteins in frontotemporal lobar degeneration and amyotrophic lateral sclerosis (FTLD/ALS).

From Osaka University 25 Aug 2020