Molecular & Structural Biology

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SIDT1 in the mammalian stomach mediates absorption of dietary miRNAs

In a new study published in Cell Research, Chen-Yu Zhang's group at Nanjing University School of Life Sciences, China, reports that SIDT1 in the mammalian stomach mediates host uptake of dietary and orally administered microRNAs (miRNAs), thus exerting biological functions in the host.

18 Aug 2020

New fluorescent probe to detect damaged mitochondria could help treat neurodegenerative disorders

Scientists have developed a new, multipurpose probe that is capable of detecting the programmed destruction of faulty mitochondria with pinpoint precision.

17 Aug 2020

Scientists describe the mechanism of action of therapeutic antibodies

Since the late 1990s, immunotherapy has been the frontline treatment against lymphomas where synthetic antibodies are used to stop the proliferation of cancerous white blood cells.

14 Aug 2020

Harnessing natural enzymes to create complex, oxygen-containing molecules

Chemists at Scripps Research have efficiently created three families of complex, oxygen-containing molecules that are normally obtainable only from plants.

14 Aug 2020

Recalling memories from an observer-like perspective activates different parts of the brain

Adopting a third-person, observer point of view when recalling your past activates different parts of your brain than recalling a memory seen through your own eyes, according to a new paper.

14 Aug 2020

Researchers use supercomputer to gain new insights into hepatitis B virus

Researchers at the University of Delaware, using supercomputing resources and collaborating with scientists at Indiana University, have gained new understanding of the virus that causes hepatitis B and the "spiky ball" that encloses the virus's genetic blueprint.

14 Aug 2020

Scientists shed new light on the evolution and function of shapes seen in nature

Researchers have shed fresh light on the evolution and function of the shapes we see in nature - using as a model the heart shaped fruits of the Capsella genus.

14 Aug 2020

Internal structure of fossilized trilobite eye found to be identical to modern bee eyes

The internal structure of a 429-million-year-old fossilized trilobite eye is almost identical to that of modern bees, according to a study published in Scientific Reports.

14 Aug 2020

Single-cell analysis uncovers new details concerning mitochondrial diseases

Investigators led by a team at Massachusetts General Hospital (MGH) have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases-- inherited disorders that interfere with energy production in the body and currently have no cure.

14 Aug 2020

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

New study shows how mitochondrial calcium transporter evolved over the years

According to a study performed by IRB Barcelona, the system that controls calcium levels in cells duplicated, giving rise to a pair of non-equivalent systems.

13 Aug 2020

Study identifies a protein that facilitates spread of SARS-CoV-2 virus through cells

Eric Ross and Sean Cascarina, biochemistry and molecular biology researchers at Colorado State University, have released a research paper identifying a protein encoded by SARS-CoV-2, the virus that causes COVID-19, that may be associated with the quick spread of the virus through cells in the human body.

13 Aug 2020

Exercise induces changes in sweat biomolecule levels, shows study

A new study shows that in addition to blood, endurance exercise induces changes in sweat biomolecule levels. These findings lay the groundwork for the development of future noninvasive exercise monitoring systems that utilize sweat as a biomarker source.

13 Aug 2020

Study shows how FAK protein is activated on lipid membranes

A team of researchers has recently described the mechanistic details regarding the activation of the Focal Adhesion Kinase (FAK) on lipid membranes.

12 Aug 2020

Enzyme in the gut could provide a useful biomarker for intestinal diseases

Enzymes used by bacteria to break down mucus in the gut could provide a useful biomarker for intestinal diseases, according to new research published in Nature Communications.

12 Aug 2020

New method helps track actin involved in mitochondrial dysfunction

The human skeleton helps in moving the body. Similarly, fine skeleton-like filaments inside the cells also help in the movement of cellular structures.

11 Aug 2020

A genetic switch in brain cells can toggle between sex-specific states when necessary

Biological sex is typically understood in binary terms: male and female. However, there are many examples of animals that are able to modify sex-typical biological and behavioral features and even change sex.

11 Aug 2020

Mathematical model shows how stability inherently arises in the brain

Whether you are playing Go in a park amid chirping birds, a gentle breeze and kids playing catch nearby or you are playing in a den with a ticking clock on a bookcase and a purring cat on the sofa, if the game situation is identical and clear, your next move likely would be, too, regardless of those different conditions.

11 Aug 2020

Finned nanoporous materials can speed up molecular transport

Thousands of chemical processes used by the energy industry and for other applications rely on the high speed of catalytic reactions, but molecules frequently are hindered by molecular traffic jams that slow them down.

11 Aug 2020

Study may reduce transmissible cancer in Tasmanian devils, offers hope for treating human cancers

A rare, transmissible tumor has brought the iconic Tasmanian devil to the brink of extinction, but new research by scientists at Washington State University and the Fred Hutchinson Cancer Research Center in Seattle indicates hope for the animals' survival and possibly new treatment for human cancers.

10 Aug 2020

Molecular & Structural Biology

SIDT1 in the mammalian stomach mediates absorption of dietary miRNAs

New fluorescent probe to detect damaged mitochondria could help treat neurodegenerative disorders

Scientists describe the mechanism of action of therapeutic antibodies

Harnessing natural enzymes to create complex, oxygen-containing molecules

Recalling memories from an observer-like perspective activates different parts of the brain

Researchers use supercomputer to gain new insights into hepatitis B virus

Scientists shed new light on the evolution and function of shapes seen in nature

Internal structure of fossilized trilobite eye found to be identical to modern bee eyes

Single-cell analysis uncovers new details concerning mitochondrial diseases

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

New study shows how mitochondrial calcium transporter evolved over the years

Study identifies a protein that facilitates spread of SARS-CoV-2 virus through cells

Exercise induces changes in sweat biomolecule levels, shows study

Study shows how FAK protein is activated on lipid membranes

Enzyme in the gut could provide a useful biomarker for intestinal diseases

New method helps track actin involved in mitochondrial dysfunction

A genetic switch in brain cells can toggle between sex-specific states when necessary

Mathematical model shows how stability inherently arises in the brain

Finned nanoporous materials can speed up molecular transport

Study may reduce transmissible cancer in Tasmanian devils, offers hope for treating human cancers

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