Molecular & Structural Biology

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New blueprint of brain connectivity provides detailed understanding of the basal ganglia

Thousands of our daily activities, from making coffee to taking a walk to saying hello to a neighbor, are made possible through an ancient collection of brain structures tucked away near the center of the cranium.

6 Apr 2021

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

For a long time, James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has investigated neglected tropical diseases, which are chronic, disabling parasitic infections mainly affecting the poor and underserved communities in developing nations.

From UC San Diego 5 Apr 2021

Study sheds new light on age-related neurodegenerative disorders

Neurons cannot simulate their DNA and hence they work continuously to repair any damage caused to their genome.

2 Apr 2021

New AI-based method can lead to faster, low-cost development of protein-based drugs

Thanks to a newly published study by scientists, artificial intelligence (AI) can now create novel and functionally active proteins.

1 Apr 2021

Supercomputer simulations help uncover the mechanism for HIV replication

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. The HIV-1 virus, like all viruses, needs to hijack a host cell through infection in order to make copies of itself.

1 Apr 2021

New atomic force microscopy enables faster, less-invasive imaging of biological samples

Kanazawa University researchers have reported a new approach of atomic force microscopy for imaging biological processes and specimens.

31 Mar 2021

Study shows how WAVE2 protein maintains the immune system balance

Sinai Health researchers have reported that they have uncovered a new mechanism that regulates harmful overreactions in the body’s immune system.

26 Mar 2021

Specific protein helps insect-eating plants trap their prey

A Venus flytrap will shut immediately just at the brush of an insect’s wing.

26 Mar 2021

Study reveals molecular mechanisms involved in the maintenance of naïve embryonic stem cells

Researchers have explained mechanisms that play a role in maintaining the embryonic stem cells in the most optimized state for use in regenerative medicine.

26 Mar 2021

Study reveals how lipids and water molecules control 5-hydroxytryptamine receptors

Serotonin, or 5-hydroxytryptamine (5-HT), is a kind of neurotransmitter. 5-HT can regulate multifaceted physiological functions such as mood, cognition, learning, memory, and emotions through 5-HT receptors.

26 Mar 2021

Silencing a key protein to “domesticate” COVID-19 virus

When cells in the human body are invaded by a virus, they send a signal to adjacent cells to boost their antiviral defenses to stop the spread of infection.

25 Mar 2021

Electron cryo-tomography reveals 3D images of sarcomeres at high resolution

Using electron cryo-tomography, researchers have created the first high-resolution 3D image of the sarcomere.

25 Mar 2021

Scientists generate a detailed molecular atlas of lung development

Researchers at the Perelman School of Medicine at the University of Pennsylvania have produced a detailed molecular atlas of lung development, which is expected to be a fundamental reference in future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs.

25 Mar 2021

Molecular & Structural Biology

New blueprint of brain connectivity provides detailed understanding of the basal ganglia

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

Study sheds new light on age-related neurodegenerative disorders

New AI-based method can lead to faster, low-cost development of protein-based drugs

Supercomputer simulations help uncover the mechanism for HIV replication

New atomic force microscopy enables faster, less-invasive imaging of biological samples

Study shows how WAVE2 protein maintains the immune system balance

Specific protein helps insect-eating plants trap their prey

Study reveals molecular mechanisms involved in the maintenance of naïve embryonic stem cells

Study reveals how lipids and water molecules control 5-hydroxytryptamine receptors

Silencing a key protein to “domesticate” COVID-19 virus

Electron cryo-tomography reveals 3D images of sarcomeres at high resolution

Scientists generate a detailed molecular atlas of lung development

New function of BMI1 gene can protect against Alzheimer’s disease

Study reveals a promising material to control root-knot nematodes

Study into cellular filopodia could optimize cancer therapy and wound closure

“Hidden genetic defects” can cause a variety of illnesses in children

Non-circulating memory T cells contribute to chronic transplant rejection

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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