Lab Automation and Bioinformatics News and Research

Latest Lab Automation and Bioinformatics News and Research

Microglia Replacement Therapy Offers Hope for Genetic Disorders Affecting the Brain

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

7 Aug 2025

New Atomic Force Microscopy Reveals Biofilm Architecture

Scientists at the Department of Energy's Oak Ridge National Laboratory have reimagined the capabilities of atomic force microscopy, or AFM, transforming it from a tool for imaging nanoscale features into one that also captures large-scale biological architecture.

6 Aug 2025

Ribosome Levels Drop During Early Brain Development

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making proteins.

6 Aug 2025

Uncovering How Cells Precisely Control Protein Production

It's known as biology's central dogma: All living organisms' genetic information is stored in DNA, which is transcribed into RNA, which is translated into proteins that perform nearly all essential tasks in a cell.

6 Aug 2025

New Computational Tool Reveals How Long Non-Coding RNAs Control Gene Expression

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed.

6 Aug 2025

Case Western Researchers Use Stem Cells to “Shut Off” Nerve Cell Strain

Amyotrophic lateral sclerosis (ALS), sometimes known as Lou Gehrig’s disease, is an incurable neurological disease that affects motor neurons, which are nerve cells in the brain and spinal cord that regulate voluntary muscle movement and breathing.

6 Aug 2025

Prime Editing Reverses Symptoms of Severe Childhood Neurological Disease

Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.

From The Jackson Labs 6 Aug 2025

Small Protein LptM Plays Key Role in Assembling Protective Outer Membrane in Bacteria

Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria.

5 Aug 2025

AI-Powered Protein Design Opens Doors to New T-Cell Based Immunotherapies

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function.

4 Aug 2025

Gene-Edited Mosquitoes Block Malaria Transmission

Genetic modification of mosquitoes with the FREP1Q224 allele shows significant promise for malaria elimination, maintaining fitness and reducing infections.

31 Jul 2025

AI-Designed Proteins Offer New Hope for Personalized Cancer Immunotherapy

Precision cancer treatment on a larger scale is moving closer after researchers have developed an AI platform that can tailor protein components and arm the patient's immune cells to fight cancer.

29 Jul 2025

Advanced Genetic Analysis with the epicGEN Solid Cancer and MSI Kit

Highly sensitive and efficient analysis with an emphasis on specific regions of the genome. epicGEN NGS panels are designed for modern diagnostic laboratories.

29 Jul 2025

Discovery of New Mitophagy Trigger Offers Hope for Parkinson’s Disease

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists at the Max Perutz Labs at the University of Vienna investigated mitophagy – a form of autophagy – and came to a remarkable conclusion: the researchers have described a new trigger for mitophagy.

29 Jul 2025

AI-Driven Precision for Next-Gen Cancer Immunotherapy

Consider how immune cells may be tailored to combat any type of cancer. T cell receptor (TCR) therapy has the potential to become the standard cancer treatment.

29 Jul 2025

Every Newborn Sequenced Within a Decade: What Does This Mean for Healthcare?

We spoke with Neil Ward from PacBio about England’s plan to introduce whole genome sequencing for every newborn, and how long-read technology is shaping the future of early diagnosis around the world.

29 Jul 2025

Rewriting rRNA Alters the Architecture of the Nucleolus

Ribosomes carry out the cell's most essential function-translating genetic information into proteins.

28 Jul 2025

Retinal Immune Response Relies on Microglia Not Neutrophils

During most eye infections or injuries, neutrophils, immune cells found in the blood, are usually the first line of defense.

28 Jul 2025

Uncovering the Molecular Roots of Neural Stem Cell Decline

Age often brings a gradual decline in the ability to learn new things and retain memories. This phenomenon, often associated with the elderly, is linked to the brain's deteriorating capacity to generate new neurons-a process that primarily occurs in the hippocampus -as neural stem cells (NSCs) divide and mature.

28 Jul 2025

New Computer Program Mimics Human and Animal Cell Behavior

Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body.

28 Jul 2025