Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Combination therapy encourages innate immune cells to eat GBM tumors

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020

A New Therapeutic Target Turns The Immune System Against Lymphoma

Non-Hodgkin lymphoma (NHL) is a group of cancers that originate in the lymph nodes and affect white blood cells of the immune system called B cells.

24 Apr 2020

Orujo Olive Oil Reduces Obesity

Researchers have confirmed that Orujo olive oil produces a significant reduction in obesity and inflammatory complications in obese mice.

24 Apr 2020

Antibodies Could Provide New Treatment For OCD

Scientists have discovered that patients suffering from OCD have increased levels of a protein called Immuno-moodulin (Imood) in their lymphocytes.

24 Apr 2020

Specialized Nerve Cells Increase The Appetite For High-Fat Foods

Researchers have discovered that a group of nerve cells promotes the consumption of high-fat food.

24 Apr 2020

A Cellular Mechanism Protecting Against Cancer

Researchers at the University of Bayreuth have discovered a natural protective mechanism that leads to the programmed death of potentially diseased cells.

24 Apr 2020

Study sheds light on the regulation of microRNAs

In all the organisms, including humans, proteins are encoded by genes and these proteins, in turn, control the body’s diverse specific cellular functions.

24 Apr 2020

DNA may not be the 'blueprint' for life, just a scrambled list of ingredients

The common view of heredity is that all information passed down from one generation to the next is stored in an organism's DNA. But Antony Jose, associate professor of cell biology and molecular genetics at the University of Maryland, disagrees.

23 Apr 2020

Researchers develop new molecular workflow to study single-cell genomics of diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

23 Apr 2020

Developing novel compounds that inhibit SARS-CoV-2 main protease

A research team from China has now created two novel compounds that block the SARS-CoV-2 main protease (Mpro).

23 Apr 2020

Study reveals the mechanism used by tuberculosis bacteria for their growth

The structure of a protein that plays a role in importing vitamin B12 into the cells of a tuberculosis (TB)-causing bacterium has been revealed by scientists from the Netherlands, Russia, the United States, and Sweden.

23 Apr 2020

Reference genes could lead to genetic improvement in wheat

Wheat sustains the world. The FAO has stated that wheat is one of the main crops in the world, both in terms of scope and production, and it is also one of the rich sources of vegetable protein and carbohydrates in the human diet.

23 Apr 2020

Preventing viral infections by protein shell misassembly

A study published recently in eLife reports new understanding of conditions that govern self-assembly in the protective shell of viruses.

23 Apr 2020

How do cells react to stressful conditions?

Most often, cells are subjected to stressful conditions that can pose a serious threat to life, for example, toxins or high temperatures.

23 Apr 2020

Researchers use CRISPR/Cas9 to search for Alzheimer's-related genes

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "molecular scissors" of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease.

22 Apr 2020

Scientists find gene signature linked to worst prognosis in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

New database of 14,000 known macrolactones could aid future drug discovery

Researchers from North Carolina State University and Collaborations Pharmaceuticals have created a free-to-use database of 14,000 known macrolactones - large molecules used in drug development - which contains information about the molecular characteristics, chemical diversity and biological activities of this structural class.

22 Apr 2020

No fuss technique for accurate characterization of gluten protein

An informative applications article from Postnova Analytics demonstrates how its Asymmetrical Field Flow Fractionation technology can be used, with no sample pre-treatment, to separate large gluten proteins and provide accurate molecular weight and molecular size data.

From Postnova Analytics 22 Apr 2020

Biophysicists uncover new features of molecular elevator

Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate transporter homolog from archaea.

21 Apr 2020

A novel prediction method for promising antiviral drug or vaccine targets

A novel method to predict the most promising targets for antiviral drugs or vaccines is based on the conformational changes viral glycoproteins go through during the process of recognition and binding to the host cell.

21 Apr 2020