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Researchers decipher genomic mechanisms involved in complex eye disease

Researchers at Tel Aviv University identified a new genetic risk factor for the complex eye disease AMD (Age-related Macular Degeneration), a leading cause for loss of eyesight at an advanced age.

7 Feb 2023

Scientists discover how a high fat diet expels gut parasitic worm

Scientists have discovered that a high-fat diet allows the immune system to eliminate a parasitic worm which is a major cause of death and illness in the developing world.

7 Feb 2023

Keanumycins: An alternative in the fight against resistant fungi

Pseudomonas bacteria produce a potent antimicrobial natural product, according to scientists at the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI).

7 Feb 2023

Treating ovarian cancer with immunotherapy involving CAR T cells

Recent research revealed that CAR T-cell therapy, a particular type of cancer treatment in which the immune system’s T cells are directed to kill tumor cells, is successful in treating ovarian cancer in mice.

7 Feb 2023

INTEGRA introduces new 8 row and 12 column automation friendly reagent reservoirs

INTEGRA Biosciences has expanded its range of products to include 8 row and 12 column automation friendly reagent reservoirs, offering a greater variety of reservoir dimensions to suit the increasing diverse applications of automated workstations.

From INTEGRA Biosciences 7 Feb 2023

“Reference Epigenome” and regulatory mechanisms in wheat embryogenesis

One of the most basic and amazing processes that occur in both plants and animals is embryogenesis. It is incredible that, within a matter of weeks after fertilization, a single mother egg cell can transform into a living thing with a complex body structure.

6 Feb 2023

Macrophages as new therapeutic target to address obesity-related diseases

Macrophages are immune system cells that control inflammation and tissue function in addition to being crucial in the early response to microbial infection. Since it aids in the repair of damaged tissue, inflammation is a natural physiological response.

6 Feb 2023

New hexameric structure of the protein triggering antibiotic resistance discovered

All living organisms require DNA replication to ensure the genetic integrity of the following generation. On the other hand, bacteria have the ability to horizontally transfer genetic information to other bacteria.

6 Feb 2023

Structure of amyloid fibers formed by the protein hnRNPDL-2 determined

Using high-resolution cryo-electron microscopy (cryo-EM), UAB researchers determined the structure of amyloid fibers formed by the protein hnRNPDL-2, which has been linked to limb-girdle muscular dystrophy type 3 and concluded that the protein’s inability to form amyloid ﬁbers, rather than aggregation, would be the cause of the disease.

6 Feb 2023

Researchers use AI to identify genes that are critical to a cancer cell’s survival

Researchers at the University of Sussex are using Artificial Intelligence (AI) technology to analyze different types of cancer cells to understand different gene dependencies, and to identify genes that are critical to a cell's survival.

6 Feb 2023

CAR T-cell therapy effective in mice with ovarian cancer

CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ImmunoTherapy of Cancer.

6 Feb 2023

Study sheds light on why lung tumors do not respond well to immunotherapy

Immunotherapy -; drug treatment that stimulates the immune system to attack tumors -; works well against some types of cancer, but it has shown mixed success against lung cancer.

6 Feb 2023

Groundbreaking discovery could lead to new ways of controlling gene regulation

UT Southwestern Medical Center researchers have discovered a method cells use to turn genes on and off that involves portions of proteins whose function has long been a mystery.

6 Feb 2023

Antibody that blocks VEGF-B could be a potential therapeutic option for fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

6 Feb 2023

Cerba Research and Teddy Lab sign Memorandum of Understanding on entering into a discussion for Joint Venture

Cerba Research announced today a Memorandum of Understanding with Teddy Clinical Research Laboratory (Wuxi, China), a preeminent central lab provider covering mainland China, to lay the foundation for an in-depth discussion towards the creation of a Joint Venture.

From Cerba Research 3 Feb 2023

Employing molecular anchor for more effective CAR immunotherapies

Researchers at St. Jude Children’s Research Hospital discovered that immune cells with the attached protein boosted the killing of cancer, irrespective of the kind of cancer cell or the type of cancer being targeted.

3 Feb 2023

Countering climate change with nanowires produced by bacteria

Rapid climate change poses a serious and immediate threat to life on Earth. As atmospheric methane traps heat 30 times more effectively than CO2, temperatures are rising as a result.

3 Feb 2023

Non-immunosuppressive strategy mitigates immune-mediated intestinal diseases

The severity of immune-mediated intestinal diseases like graft-versus-host disease (GVHD) or inflammatory bowel disease is known to be associated with changes in the gut microbiome, but what causes such disruption in the microbial community is unknown.

3 Feb 2023

Experimental optimization of prime editing to achieve high efficiency

Genome editing technologies have enormous potential for treating genetic diseases. Techniques like the extensively used CRISPR/Cas9 gene scissors target the source of the disease directly in the DNA.

3 Feb 2023