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Study charts seasonal and circadian genetic variation across the human body

The daily rotation of Earth and its yearly voyage around the Sun marks the natural rhythm of life on the planet.

14 Feb 2023

Study finds similar levels of DNA damage in vapers and smokers

E-cigarettes-; used regularly by more than 10% of U.S. teens and more than 3% of adults-; were once pitched as a healthy alternative to tobacco cigarettes.

14 Feb 2023

Blastocystis can promote or disrupt gut health, study finds

The gut microbiota contains trillions of bacteria that can promote health or cause disease under different conditions.

14 Feb 2023

UChicago scientists shed light on the longstanding puzzle of RNA methylation

University of Chicago scientists have discovered a new wrinkle in our understanding of how our genes work.

14 Feb 2023

Study explains why cancers stop responding to kinase inhibitors and come back stronger

More than 70 FDA-approved cancer drugs are kinase inhibitors, which work by blocking kinases-;enzymes that add phosphate groups to molecules in the cell-;and preventing the chemical activity necessary for signaling and growth in cancer cells.

14 Feb 2023

Researchers discover target enzyme for blast disease

A fungus that plagues rice crops worldwide gains entry to plant cells in a way that leaves it vulnerable to simple chemical blockers, a discovery that could lead to new fungicides to reduce the substantial annual losses of rice and other valuable cereals.

14 Feb 2023

Research provides insight into the regulation of heartbeats

UT Southwestern Medical Center researchers have mapped gene control elements in specialized cardiac cells responsible for coordinating heartbeats. The findings of the genome exploration study, published in The Journal of Clinical Investigation, provide insight into how heartbeats are regulated and could impact diagnosis and risk prediction for a variety of common arrhythmias.

14 Feb 2023

Importance of drying temperature in the technological properties of OSPF

Orange, starchy sweet potatoes are great mashed, cut into fries or just roasted whole. But you likely haven't considered grinding them into a flour and baking them into your next batch of cookies -; or at least, not yet!

14 Feb 2023

Novel analytical platform quantitatively characterizes mRNA vaccines

Researchers from Tokyo Metropolitan University and RIKEN CSRS have developed a new analytical platform based on liquid chromatography, mass spectrometry and software analysis that quantifies the structure of messenger RNA (mRNA) based medicines.

14 Feb 2023

Study reveals the mechanisms that prevent effective cancer cell death

Cancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors and oncogenes. Mutations in tumor suppressor genes can allow tumors to grow unchecked – a case of no brakes – while mutations in oncogenes can activate cell proliferation, pushing the gas pedal all the way to the floor.

14 Feb 2023

New software helps identify genes that play vital roles in the development

Computer software developed at Washington University School of Medicine in St. Louis can predict what happens to complex gene networks when individual genes are missing or dialed up more than usual.

14 Feb 2023

Robust new method accurately identifies eight antidepressants

In recent years, a mass spectrometry process that can detect the amounts of drugs in a biological sample, such as blood, has become a powerful diagnostic tool for helping medical professionals identify and monitor levels of therapeutic drugs in patients, which can cause unwanted or dangerous side effects.

14 Feb 2023

Review highlights the pathological significance of CEACAM1, 5, and 6

A new review was published in Genes & Cancer on February 1, 2023, entitled, "CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens."

14 Feb 2023

BlueRemediomics aims to synergize marine microbiome data and biobank resources from across Europe

The European Commission has funded the BlueRemediomics project, which will develop novel tools and approaches to cataloguing marine microbiome data and marine culture collections.

13 Feb 2023

Extracts from two common wild plants block SARS-CoV-2 from entering human cells

Two common wild plants contain extracts that inhibit the ability of the virus that causes COVID-19 to infect living cells, an Emory University study finds.

13 Feb 2023

New method maps spontaneous formation of protein-rich droplets

Terahertz spectroscopy maps spontaneous formation of protein-rich droplets that may lead to neurodegenerative diseases.

13 Feb 2023

Engineering a phage's DNA by introducing modified CRISPR-Cas machinery genes

Bacteriophages (or phages) are viruses that infect bacteria. They are the most abundant biological entity, and they can be found wherever bacteria live. To propagate themselves, phages inject their DNA into their bacterial hosts.

13 Feb 2023

New models provide better understanding of how life originated

The first signs of life emerged on Earth in the form of microbes about four billion years ago. While scientists are still determining exactly when and how these microbes appeared, it's clear that the emergence of life is intricately intertwined with the chemical and physical characteristics of early Earth.

13 Feb 2023

Two-step screening of aroma compounds reveals a novel and effective modulator of dendritic cells

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

13 Feb 2023

New route to understanding the origins of life

A team of scientists from France and Austria has discovered a new abiotic pathway for the formation of peptide chains from amino acids - a key chemical step in the origin of life.

13 Feb 2023