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Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Why is Innovation Critical to Life Sciences Research?

In this interview, we speak to Kirstie Speck from Abcam about the importance of innovation within the life sciences and how its role will change over the next 10 years.

From Abcam 13 Dec 2021

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

New mechanism makes cells under stress conditions stop their polarized growth

The Oxidative Stress and Cell Cycle Research Group at UPF has discovered a mechanism whereby cells under stress conditions stop their polarized growth. The study, published in the journal Cell Reports, was led by Elena Hidalgo and José Ayté, and the first author is Clàudia Salat-Canela.

13 Dec 2021

Common plants are displacing rarer plant species, study shows

"Common species" are on the advance in several ecosystems in Europe and are displacing rarer plant species. As a result, the plant communities become more and more similar.

13 Dec 2021

Research offers alternative cell option for organs-on-chips

Organ-on-a-chip technology has provided a push to discover new drugs for a variety of rare and ignored diseases for which current models either don't exist or lack precision. In particular, these platforms can include the cells of a patient, thus resulting in patient-specific discovery.

13 Dec 2021

New technology can help detect the activity of CRISPR gene editing tools

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at the Department of Energy's Oak Ridge National Laboratory.

13 Dec 2021

Sustainable dietary habits are linked to health benefits, says study

Large population research from Lund University in Sweden has revealed that sustainable dietary habits are associated with health benefits like a decreased risk of premature death from cancer and cardiovascular disease.

13 Dec 2021

Detachable head-mounted photoacoustic microscope images brain activity in mice

Scientists recently generated the first detachable head-mounted photoacoustic microscope for imaging brain activity in freely roaming mice.

13 Dec 2021

Study helps identify how immune system cells identify and eradicate tumors

In the last 10 years, immunotherapy has been used to save the lives of several cancer patients with lung cancer.

13 Dec 2021

Study shows how proteases help keep cells clean

Waste collectors collect and dispose of household waste. In cells, a similar process works to eliminate damaged and potentially hazardous proteins.

13 Dec 2021

Researchers regenerate cartilage using novel protein fragment

The existing methods for the regeneration of injured cartilage generate tissue that breaks down. This deterioration eventually leads to osteoarthritis—the commonly seen form of arthritis—affecting over 32.5 million grown-ups in the United States, as per the Centers for Disease Control and Prevention.

13 Dec 2021

Cocktails of llama nanobodies effective against COVID-19 variants, says study

According to recent research, cocktails of small llama antibodies against SARS-CoV-2—the causative agent of COVID-19—can help fight novel variants of the virus.

13 Dec 2021

Experts grow novel cell lines in a chemically defined medium

Researchers for the first time acquired stem cells from livestock that was grown under chemically defined conditions.

13 Dec 2021

Multiple exposure enhances antibody efficacy against COVID-19 variants

Antibodies produced by the immune system against the SARS-CoV-2 spike protein help pinpoint and avoid future infections.

13 Dec 2021

Review: Transmission, origin, pathogenesis, animal model and diagnosis of Zika virus

Announcing a new article publication for Zoonoses journal. Dallas Vue and Qiyi Tang from Howard University College of Medicine, Washington, DC, USA review transmission, origin, pathogenesis, animal model and diagnosis of Zika Virus.

10 Dec 2021

Battery-free, wearable device could quantify airborne nicotine exposure from e-cigarettes

Some studies have shown that nicotine, an addictive substance in electronic cigarettes, increases the risk of cardiovascular and respiratory disorders.

10 Dec 2021

Powering the Biotechnology Revolution through Cloud R&D

In this interview, we speak to Sajith Wickramasekara, CEO and Co-Founder of Benchling, about cloud R&D and how it is powering the biotechnology revolution.

From Benchling 10 Dec 2021

New classification method divides breast cancers into 12 distinct biological groups

Researchers at UNC Lineberger Comprehensive Cancer Center have taken a major step forward in melding two key methods for studying breast cancer: one by genetic analysis and the second by looking at the architecture of cells, or their pathology.

9 Dec 2021

Commonly used drugs have powerful effects on the gut microbiome, research shows

We are one of the most medicated generations of humans to live on our planet. Cardiometabolic diseases like type 2 diabetes, obesity, and coronary artery disease continue to increase in prevalence and together constitute the highest cause of mortality worldwide.

9 Dec 2021