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Researchers demonstrate the impact of epithelial cells, mammary microenvironment on breast cancer cells

The cover for issue 30 of Oncotarget features Figure 4, "RNAseq results demonstrating differences between normal, cancer, and redirected cells," by Frank-Kamenetskii, et al. which reported that the influence of breast cancer cells on normal cells of the microenvironment, such as fibroblasts and macrophages, has been heavily studied but the influence of normal epithelial cells on breast cancer cells has not.

19 Oct 2020

Chemist receives NIH grant to provide new framework for novel flu vaccines

Chemist Mahmoud Moradi has received a $422,579 grant from the National Institutes of Health to advance his work modeling hemagglutinin, the critical protein of the influenza virus.

19 Oct 2020

Cheese-ripening bacteria respond to volatile gases produced by fungi

Scientists have discovered that fungi use many ways to interact with bacteria and one of these methods is through the smells emitted by cheese.

19 Oct 2020

UNM researchers identify medications that could help fight COVID-19 infection

University of New Mexico researchers who combed through a "library" of previously approved drugs believe they have identified a medication with the potential to help speed a patient's recovery from SARS-CoV-2 infection.

19 Oct 2020

New nanoparticles can destroy drug-resistant cancer cells

Multidrug resistance, or MDR, is a process in which tumors become impervious to numerous drugs and is a major cause of failure in cancer chemotherapy.

19 Oct 2020

Atmospheric science professor identifies ways to reduce false alarms on climate change

In this year of extreme weather events -- from devastating West Coast wildfires to tropical Atlantic storms that have exhausted the alphabet -- scientists and members of the public are asking when these extreme events can be scientifically linked to climate change.

19 Oct 2020

Researchers identify “silent” mutations in the genetic code of COVID-19 virus

We know that the coronavirus behind the COVID-19 crisis lived harmlessly in bats and other wildlife before it jumped the species barrier and spilled over to humans.

19 Oct 2020

Bioinformatics expert to design antibody-antigen interface to predict peptide sequences

Dmitri Klimov, Professor, Bioinformatics and Computational Biology, is creating a computational platform for designing an antibody-antigen interface based on DNA origami.

19 Oct 2020

New tool can provide non-invasive decision support for treating lung cancer

Personalized treatment options for patients with lung cancer have come a long way in the past two decades. For patients with non-small cell lung cancer, the most common subtype of lung cancer and the leading cause of cancer-related death worldwide, two major treatment strategies have emerged: tyrosine kinase inhibitors and immune checkpoint inhibitors.

19 Oct 2020

Researchers develop a new method for siRNA stabilization

In the gene controlling mechanism, known as RNA interference, the expression of particular genes is downregulated by siRNAs or endogenic microRNAs.

19 Oct 2020

Study shows antibody levels drop rapidly in recovering COVID-19 patients

The lack of effective treatments for COVID-19 is forcing hospitals to use blood plasma from recovering patients to treat those who have severe symptoms.

19 Oct 2020

Fertilization of paddy soil can help reduce greenhouse gases

A soil scientist from RUDN University discovered the effect of fertilization on the ability of the soil to retain carbon. To understand this mechanism, he and his team studied the movement of organic carbon in the soil of rice paddies.

19 Oct 2020

A new strategy for capturing atmospheric carbon dioxide

Climate change caused by emissions of greenhouse gases into the atmosphere is a most important issue for our society. Acceleration of global warming results in catastrophic heatwaves, wildfires, storms and flooding.

19 Oct 2020

New mechanism of metastatic cancer cells discovered in substrates of different stiffness

During metastasis, cancer cells actively interact with microenvironments of new tissues. How metastatic cancer cells respond to new environments in the secondary tissues is a crucial question in cancer research but still remains elusive.

19 Oct 2020

Plant genetic engineering can help address micronutrient malnutrition

More than two billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

19 Oct 2020

Researchers develop model to encode established biochemical principles at cellular level

The most important components for the functioning of a biological cell are its proteins. As a result, protein production is arguably the most important process for cell growth. The faster the bacterial growth rate, the faster protein synthesis needs to take place.

19 Oct 2020