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New label-free immune profiling assay to assess rapidly changing host immune response

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP), an Interdisciplinary Research Group (IRG) at the Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have developed a new label-free immune profiling assay that profiles the rapidly changing host immune response in case of infection, in a departure from existing methods that focus on detecting the pathogens themselves, which can often be at low levels within a host.

26 Mar 2021

Depletion of stem cells could be a significant factor behind miscarriage

Depletion of a certain type of stem cell in the womb lining during pregnancy could be a significant factor behind miscarriage, according to a study released today in STEM CELLS. The study, by researchers at Warwick Medical School, University of Warwick, Coventry, England, reports on how recurrent pregnancy loss is a result of the loss of decidual precursor cells prior to conception.

26 Mar 2021

Study reveals how lipids and water molecules control 5-hydroxytryptamine receptors

Serotonin, or 5-hydroxytryptamine (5-HT), is a kind of neurotransmitter. 5-HT can regulate multifaceted physiological functions such as mood, cognition, learning, memory, and emotions through 5-HT receptors.

26 Mar 2021

Toxin in potatoes is a divergent of bitter-tasting compound in tomatoes

A multi-institutional collaboration has revealed that α-solanine, a toxic compound found in potato plants, is a divergent of the bitter-tasting α-tomatine, which is found in tomato plants.

26 Mar 2021

Study of leaf size in grasses can help accurately model the effects of climate change

One-third of the Earth's surface is covered by more than 11,000 grass species -- including crops like wheat, corn, rice and sugar cane that account for the bulk of the world's agricultural food production and important biofuels. But grass is so common that few people realize how diverse and important it really is.

26 Mar 2021

Researchers use mathematical modeling to explain CAR T-cell therapy dynamics

Chimeric antigen receptor T-cell therapy, or CAR T, is a relatively new type of therapy approved to treat several types of aggressive B cell leukemias and lymphomas.

26 Mar 2021

Scientists identify new biomarkers in the blood of patients with malignant melanoma

A team of researchers has studied the molecular profile of small “messenger” vesicles called exosomes, produced by cancer stem cells (CSCs), which play a key role in the process of carcinogenesis and metastasis in the blood of patients with malignant melanoma.

26 Mar 2021

Smart data helps food producers to yield reliable business forecasts

Food production is a complex process involving the careful monitoring and management of raw materials, supply chains, market prices and much more besides.

26 Mar 2021

Xylem filters from native trees help purify drinking water

The interiors of nonflowering trees such as pine and ginkgo contain sapwood lined with straw-like conduits known as xylem, which draw water up through a tree's trunk and branches. Xylem conduits are interconnected via thin membranes that act as natural sieves, filtering out bubbles from water and sap.

From Massachusetts Institute of Technology (MIT) 26 Mar 2021

New chilli hybrids can have better disease resistance, boost productivity

Researchers exploring the genetics of chili pepper species have identified an entire host of new hybrids of chilies hybrids.

From University of Bath 25 Mar 2021

Silencing a key protein to “domesticate” COVID-19 virus

When cells in the human body are invaded by a virus, they send a signal to adjacent cells to boost their antiviral defenses to stop the spread of infection.

25 Mar 2021

Study shows how a subset of T cells is generated in melanoma survivors affected by vitiligo

A few patients suffering from melanoma are known to respond quite well to immunotherapy and experience significant and long-lasting tumor regression.

25 Mar 2021

Electron cryo-tomography reveals 3D images of sarcomeres at high resolution

Using electron cryo-tomography, researchers have created the first high-resolution 3D image of the sarcomere.

25 Mar 2021

Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Immunotherapy, which recruits the body's own immune system to attack cancer, has given many cancer patients a new avenue to treat the disease.

25 Mar 2021

Scientists generate a detailed molecular atlas of lung development

Researchers at the Perelman School of Medicine at the University of Pennsylvania have produced a detailed molecular atlas of lung development, which is expected to be a fundamental reference in future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs.

25 Mar 2021

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread.

From National Cancer Institute (NCI) 25 Mar 2021

Monitoring pollen levels using environmental DNA

In this interview, AZoLifeSciences speaks to Dr. Ben Wheeler about his latest research and how we monitor pollen levels using environmental DNA.

From University of Exeter 25 Mar 2021

Study shows SARS-CoV-2 antibodies wane at different rates

Researchers from Duke-NUS Medical School, the National Centre for Infectious Diseases (NCID), and the Agency for Science, Technology and Research (A*STAR) Infectious Diseases Labs have discovered that antibodies against SARS-CoV-2 decline at different speeds, and these antibodies last for only a few days in some people but remain for many years in other individuals.

24 Mar 2021

Gender difference accounts for major psychiatric disorders

According to an analysis of sex variations in the genetics of bipolar disorder, schizophrenia, and major depressive disorders.

24 Mar 2021

New function of BMI1 gene can protect against Alzheimer’s disease

The Maisonneuve-Rosemont Hospital Research Centre has taken another step toward interpreting Alzheimer’s disease.

24 Mar 2021

Life Science News

New label-free immune profiling assay to assess rapidly changing host immune response

Depletion of stem cells could be a significant factor behind miscarriage

Study reveals how lipids and water molecules control 5-hydroxytryptamine receptors

Toxin in potatoes is a divergent of bitter-tasting compound in tomatoes

Study of leaf size in grasses can help accurately model the effects of climate change

Researchers use mathematical modeling to explain CAR T-cell therapy dynamics

Scientists identify new biomarkers in the blood of patients with malignant melanoma

Smart data helps food producers to yield reliable business forecasts

Xylem filters from native trees help purify drinking water

New chilli hybrids can have better disease resistance, boost productivity

Silencing a key protein to “domesticate” COVID-19 virus

Study shows how a subset of T cells is generated in melanoma survivors affected by vitiligo

Electron cryo-tomography reveals 3D images of sarcomeres at high resolution

Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Scientists generate a detailed molecular atlas of lung development

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Monitoring pollen levels using environmental DNA

Study shows SARS-CoV-2 antibodies wane at different rates

Gender difference accounts for major psychiatric disorders

New function of BMI1 gene can protect against Alzheimer’s disease

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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