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Researchers Discover Key Factor Behind Disease Resistance in Gene Carriers

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms.

3 Jan 2025

New Insights into How Early Life Experiences Influence Genetic Expression and Brain Health

In a comprehensive Genomic Press Interview, renowned neuroscientist Dr. Michael Meaney reveals pivotal discoveries about the intricate relationship between genes and environment in shaping brain health.

2 Jan 2025

New Sequencing Method Unveils Adaptive States and Host-Phage Interactions in the Gut

The human gut microbiome is complex and diverse, with significant implications for health and disease. The study develops smRandom-seq2, a droplet-based method that overcomes the limitations of existing techniques by capturing RNA from a wide variety of species.

2 Jan 2025

New Model for Studying Ebola Virus Pathogenesis

Ebola is a fatal hemorrhagic disease caused by a virus that is found in parts of East-Central and West Africa. Most individuals are aware that the major mode of person-to-person transmission is through contact with an infected person’s bodily fluids.

2 Jan 2025

Bumetanide Treatment Alters Early and Late Social Behaviors in Fragile X Mice

In a comprehensive Genomic Press Interview, researchers from the University of Texas Health Science Center at San Antonio and Hirosaki University have uncovered critical new insights into the developmental trajectory of social behaviors in fragile X syndrome, the leading genetic cause of autism spectrum disorder.

30 Dec 2024

Scientists Develop Non-Destructive Method to Study Fish Teeth

Can we examine the teeth of living fish and other vertebrates in detail, repeatedly over time, without harming them?

27 Dec 2024

Discovery of ALAS1's Secret Role Could Boost Cancer Therapy Development

In everyday life, when things turn out the opposite of what you expect, it's usually cause for frustration. In science, it's often the starting point for discovery.

23 Dec 2024

New Genetic Link to Autism Identified

New research published in The American Journal of Human Genetics has identified a previously unknown genetic link to autism spectrum disorder (ASD). The study found that variants in the DDX53 gene contribute to ASD, providing new insights into the genetic underpinnings of the condition.

20 Dec 2024

Extracellular Vesicles from Mesenchymal Stromal Cells Restore Joint Health in Osteoarthritis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21 on November 22, 2024, entitled, "Anti-aging effect of extracellular vesicles from mesenchymal stromal cells on senescence-induced chondrocytes in osteoarthritis."

20 Dec 2024

Overactive Chemoreceptors Affect Cardiovascular and Metabolic Consequences of Type 2 Diabetes

Researchers from the University of Missouri are studying potential therapies to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes.

20 Dec 2024

ALS Stem Cell Model Reveals Increased Susceptibility to Cell Death

Amyotrophic lateral sclerosis (ALS) is a fast-progressing neurodegenerative disease with an average survival time of three years. In ALS, certain types of neurons called motor neurons that are required for muscle contractions die off, leading to progressive paralysis affecting most muscles of the body. The molecular causes of ALS are poorly understood, and effective treatments are missing.

20 Dec 2024

Scientists Discover Key to Overcoming Cancer's Evasion Tactics

A cunning culprit that aids cancer cells in avoiding CAR T cell therapy has been identified by researchers at City of Hope®, one of the biggest and most cutting-edge cancer research and treatment organizations in the United States, with a comprehensive cancer center in Los Angeles that is ranked among the top five cancer centers in the country by US News & World Report.

18 Dec 2024

Terumo Blood and Cell Technologies Presents Data on Automated Red Blood Cell Exchange to Treat Sickle Cell Disease at the American Society of Hematology

The abstracts highlight the potential to improve SCD treatment using aRBCX. The first poster presents data from U.S. insurance claims, examined in a study performed with researchers at University of Pittsburgh.

18 Dec 2024

Exploring the Potential of Probiotics to Restore Gut Microbiota After Antibiotic Disruption

Antibiotics are important clinical tools for treating bacterial infections, yet we recognize that an important side effect of antibiotic use is disruption of the microbial community living in the human gut.

17 Dec 2024

Single-Cell RNA Sequencing Sheds Light on Craniopharyngioma Tumor Subtypes

Craniopharyngiomas are brain tumors that negatively impact the hormonal function of the nearby pituitary.

17 Dec 2024

Stem Cell-Derived Brain Organoids Model Mitochondrial Diseases

Mini-brains, also known as brain organoids, have been created by researchers at the University of Bergen using cutting-edge stem cell technology.

16 Dec 2024

Targeting Cancer with Nanoparticle-Delivered Gene Therapy

Scientists are literally shining a laser on the energy centers of cancer cells in an attempt to harm these sources of power and cause widespread cancer cell death.

16 Dec 2024

Deadly Mould Strains Highly Likely to Acquire Resistance to New Drugs

Scientists have identified strains of one of the world’s most dangerous fungal pathogens, already resistant to our most effective antifungal drugs, which are also 5-times more likely to acquire resistance to desperately needed new treatments in development.

From The University of Manchester 16 Dec 2024

New Imaging Method Reveals Sharper Layers of Cells in Living Tissue

Metabolic imaging is a noninvasive method that enables clinicians and scientists to study living cells using laser light, which can help them assess disease progression and treatment responses.

12 Dec 2024

Exosome-Mediated Immune Escape and Tumor Growth in Hepatocellular Carcinoma

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME attempts to eliminate abnormal cells through immune surveillance.

12 Dec 2024

Clinical News and Research

Researchers Discover Key Factor Behind Disease Resistance in Gene Carriers

New Insights into How Early Life Experiences Influence Genetic Expression and Brain Health

New Sequencing Method Unveils Adaptive States and Host-Phage Interactions in the Gut

New Model for Studying Ebola Virus Pathogenesis

Bumetanide Treatment Alters Early and Late Social Behaviors in Fragile X Mice

Scientists Develop Non-Destructive Method to Study Fish Teeth

Discovery of ALAS1's Secret Role Could Boost Cancer Therapy Development

New Genetic Link to Autism Identified

Extracellular Vesicles from Mesenchymal Stromal Cells Restore Joint Health in Osteoarthritis

Overactive Chemoreceptors Affect Cardiovascular and Metabolic Consequences of Type 2 Diabetes

ALS Stem Cell Model Reveals Increased Susceptibility to Cell Death

Scientists Discover Key to Overcoming Cancer's Evasion Tactics

Terumo Blood and Cell Technologies Presents Data on Automated Red Blood Cell Exchange to Treat Sickle Cell Disease at the American Society of Hematology

Exploring the Potential of Probiotics to Restore Gut Microbiota After Antibiotic Disruption

Single-Cell RNA Sequencing Sheds Light on Craniopharyngioma Tumor Subtypes

Stem Cell-Derived Brain Organoids Model Mitochondrial Diseases

Targeting Cancer with Nanoparticle-Delivered Gene Therapy

Deadly Mould Strains Highly Likely to Acquire Resistance to New Drugs

New Imaging Method Reveals Sharper Layers of Cells in Living Tissue

Exosome-Mediated Immune Escape and Tumor Growth in Hepatocellular Carcinoma

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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