Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Identifying genetic factors that mitigate the risk of diabetes

A rice-based diet is a traditional food among certain east-Asian population and has ushered in several genomic adaptations that may play a role in obesity.

22 Sep 2020

Protein in the pancreas protects beta-cells from high-fat diet induced stress

Every time we eat, the glucose level in our body goes up. This spurs our pancreatic machinery into action and through intricate physiological mechanisms, appropriate amounts of insulin are produced, our blood glucose levels are controlled, and we remain healthy.

17 Sep 2020

Study offers insight on how muscles and fat tissue communicate to improve fitness

Why does exercise training make you more fit? It's well established that exercising enhances insulin sensitivity and improves our metabolism that, in turn, increases exercise performance. But the biological mechanisms underlying this adaptation are not fully understood.

15 Sep 2020

Treatments targeting the gut microbiome can protect space travelers from adverse health problems

Space travelers who spend long periods of time in space can experience health problems, such as adverse effects on metabolism, and immunity.

9 Sep 2020

Study shows different cell response offers more control to muscles

Slight variations in individual muscle cell contractions enable the whole muscle to bend with more precision and control.

2 Sep 2020

New method shows promise for treating diabetes and obesity

Obesity, the leading cause of type 2 diabetes and chronic illnesses, will collectively kill more people around the world in 2020 than COVID-19 coronavirus.

1 Sep 2020

Study shows how DUSP8 protein regulates glucose tolerance, insulin sensitivity

The brain plays a major role in controlling our blood glucose levels. In type 2 diabetics this glucose metabolism brain control is often dysfunctional. Genetic components for this phenomenon have so far remained elusive.

24 Aug 2020

Study examines the impact of low-carb, high-fat diet in older people

A new study, published in Nutrition and Metabolism, from researchers with the University of Alabama at Birmingham's Nutrition Obesity Research Center observed improvements in body composition, fat distribution and metabolic health in response to an eight-week, very low-carbohydrate diet.

21 Aug 2020

Exposure to air pollution may increase risk of cardiometabolic diseases

Air pollution is the world's leading environmental risk factor, and causes more than nine million deaths per year.

21 Aug 2020

Newly developed transplantable human cells can help cure type 1 diabetes

Researchers have made a significant advancement in the quest for a safe, effective treatment for type 1 diabetes.

20 Aug 2020

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

20 Aug 2020

Elevated levels of heart failure marker increase risk for diabetes-related complications

Healthy people - especially women - with elevated levels of the heart failure marker NT-proBNP have a lower risk of developing type 2 diabetes.

19 Aug 2020

Shielded stem cells can improve heart healing

Ghanta, R.K., et al. (2020) Immune-modulatory alginate protects mesenchymal stem cells for sustained delivery of reparative factors to ischemic myocardium. Biomaterials Science. doi.org/10.1039/D0BM00855A.

19 Aug 2020

Increased fructose intake during pregnancy can alter offspring's metabolism

An increased level of fructose intake during pregnancy can cause significant changes in maternal metabolic function and milk composition and alter the metabolism of their offspring, researchers from the University of Otago, Wellington, have found.

19 Aug 2020

Simple blood test is useful in screening youth for prediabetes and diabetes

A simple blood test that does not require overnight fasting has been found to be an accurate screening tool for identifying youth at risk for type 2 diabetes and heart disease risk later in life, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

11 Aug 2020

Metabolic "switch" may offer clues to increased risk of glucose intolerance in post-menopausal women

Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have discovered neural mechanisms in mice specific to females that can shift estrogen from playing a protective role in glucose metabolism to one that is disruptive.

7 Aug 2020

Insulin News and Research

Identifying genetic factors that mitigate the risk of diabetes

Protein in the pancreas protects beta-cells from high-fat diet induced stress

Study offers insight on how muscles and fat tissue communicate to improve fitness

Treatments targeting the gut microbiome can protect space travelers from adverse health problems

Study shows different cell response offers more control to muscles

New method shows promise for treating diabetes and obesity

Study shows how DUSP8 protein regulates glucose tolerance, insulin sensitivity

Study examines the impact of low-carb, high-fat diet in older people

Exposure to air pollution may increase risk of cardiometabolic diseases

Newly developed transplantable human cells can help cure type 1 diabetes

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Elevated levels of heart failure marker increase risk for diabetes-related complications

Shielded stem cells can improve heart healing

Increased fructose intake during pregnancy can alter offspring's metabolism

Simple blood test is useful in screening youth for prediabetes and diabetes

Metabolic "switch" may offer clues to increased risk of glucose intolerance in post-menopausal women

Researchers identify receptor responsible for activating energy-burning property of brown fat

Study may help identify women at risk of developing type 2 diabetes after pregnancy

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Genetic analysis helps determine causal relationships between diabetes, obesity and NAFLD

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