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Zebrafish Protein Promotes Cardiac Repair in Mice

Researchers from the Hubrecht Institute's Bakkers group have used a zebrafish protein to successfully repair damaged mouse hearts.

3 Jan 2025

New Insights into How Early Life Experiences Influence Genetic Expression and Brain Health

In a comprehensive Genomic Press Interview, renowned neuroscientist Dr. Michael Meaney reveals pivotal discoveries about the intricate relationship between genes and environment in shaping brain health.

2 Jan 2025

New Sequencing Method Unveils Adaptive States and Host-Phage Interactions in the Gut

The human gut microbiome is complex and diverse, with significant implications for health and disease. The study develops smRandom-seq2, a droplet-based method that overcomes the limitations of existing techniques by capturing RNA from a wide variety of species.

2 Jan 2025

Uncovering the Cellular Mechanisms of Brain Aging

Not all brain cell types age in the same way, according to new brain mapping research supported by the National Institutes of Health (NIH).

2 Jan 2025

Bumetanide Treatment Alters Early and Late Social Behaviors in Fragile X Mice

In a comprehensive Genomic Press Interview, researchers from the University of Texas Health Science Center at San Antonio and Hirosaki University have uncovered critical new insights into the developmental trajectory of social behaviors in fragile X syndrome, the leading genetic cause of autism spectrum disorder.

30 Dec 2024

AI-Designed Nanocages Mimic Intricate Structures of Viruses

Professor Sangmin Lee from POSTECH's Department of Chemical Engineering, in collaboration with 2024 Nobel Chemistry Laureate Professor David Baker from the University of Washington, has developed an innovative therapeutic platform by mimicking the intricate structures of viruses using artificial intelligence (AI).

26 Dec 2024

Fruit Flies Evolve New Defense Through Gene Transfer

In the continual arms race between parasites and their hosts, innovation was thought to be the key to a successful attack or defense that one-ups the competition.

26 Dec 2024

New Gene Editing Tool Targets Alzheimer's by Skipping Disease-Causing Gene Segments

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report.

24 Dec 2024

Plant Research Reveals Unexpected Function for Key Cellular Protein

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's genetic code expresses itself. The fundamental breakthrough was discovered in apple cells but is relevant to all living organisms made of nucleus-containing cells, including humans.

24 Dec 2024

New Synthetic Biology Tool Improves Genetic Circuit Integration and Functionality

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic Translational Coupling Element (SynTCE),' significantly enhancing the precision and integration density of genetic circuits in synthetic biology.

23 Dec 2024

Discovery of ALAS1's Secret Role Could Boost Cancer Therapy Development

In everyday life, when things turn out the opposite of what you expect, it's usually cause for frustration. In science, it's often the starting point for discovery.

23 Dec 2024

New Genetic Link to Autism Identified

New research published in The American Journal of Human Genetics has identified a previously unknown genetic link to autism spectrum disorder (ASD). The study found that variants in the DDX53 gene contribute to ASD, providing new insights into the genetic underpinnings of the condition.

20 Dec 2024

New Insights into Pseudomonas syringae Toxin’s Impact on Non-Flowering Plants

The capacity of bacteria to spread disease across the Plant Kingdom may be much more widespread than previously suspected, according to new analysis.

20 Dec 2024

Engineering Yeast Promoters for Biologic Manufacturing

When introducing genes into yeast to make it produce drugs and other useful substances, it is also necessary to reliably switch the production on or off. A Kobe University team found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production.

19 Dec 2024

Scientists Mimic Fungal Process to Create Novel Medicines

Since the unintentional 1928 discovery of penicillin by Alexander Fleming, fungi have been a treasure trove of medicinal compounds for almost a century.

19 Dec 2024

New Virus Found to Alter Cell Machinery in Eukaryotic Cells

Julie Thomy, lead author of the study and postdoctoral researcher in the Daniel K. Inouye Center for Microbial Oceanography: Research and Education (C-MORE) and Department of Oceanography in the UH Mānoa School of Ocean and Earth Science and Technology (SOEST)

18 Dec 2024

Space Experiment Reveals Surprising Brain Cell Behavior

Microgravity exposure accelerates brain cell development in organoids, revealing potential implications for neurodegenerative disease research and space health.

18 Dec 2024

New Strategy to Combat Antibiotic-Resistant Bacteria

The discovery of a vulnerability in antibiotic resistance mechanisms may lead to improved strategies for combating superbugs and enhancing current therapies.

18 Dec 2024

Scientists Discover Key to Overcoming Cancer's Evasion Tactics

A cunning culprit that aids cancer cells in avoiding CAR T cell therapy has been identified by researchers at City of Hope®, one of the biggest and most cutting-edge cancer research and treatment organizations in the United States, with a comprehensive cancer center in Los Angeles that is ranked among the top five cancer centers in the country by US News & World Report.

18 Dec 2024