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Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread.

From National Cancer Institute (NCI) 25 Mar 2021

Non-circulating memory T cells contribute to chronic transplant rejection

The main function of non-circulating memory T cells is to offer local protection against re-infection.

From University of Pittsburgh 22 Mar 2021

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

A study headed by UCM reports that polymorphisms in gene TGFB1 and low plasma levels of protein TGFB1 serve as biomarkers for the gastric adenocarcinoma prognosis.

19 Mar 2021

New “genome scalpel” can rapidly trim microalgal genomes

A single-celled alga removes non-essential pieces by undergoing genome surgery.

18 Mar 2021

Lowering apolipoprotein CIII levels can prevent deleterious effects of a high-fat diet

Consumption of a diet with high fat levels increases the risk of fatty liver, obesity, cardiovascular diseases, and type 2 diabetes.

15 Mar 2021

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Scientists have created a CRISPR-based gene editor named C-to-G Base Editor (CGBE) that can correct mutations responsible for genetic disorders.

15 Mar 2021

Targeted immunotherapy could improve radiotherapy response in cancer cells

Cancers that are resistant to radiotherapy could be rendered susceptible through treatment with immunotherapy, a new study suggests.

9 Mar 2021

Researchers identify gene variant associated with childhood asthma

Researchers at Henry Ford Health System, as part of a national asthma collaborative, have identified a gene variant associated with childhood asthma that underscores the importance of including diverse patient populations in research studies.

1 Mar 2021

Study identifies how CTLA-4 blockade can disable suppressive immune cells to aid tumor destruction

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

18 Feb 2021

Protein imbalance leads to cataract

Cataracts are the most prevalent eye disease in humans. But despite this fact, the actual processes that lead to this disease are not entirely known.

17 Feb 2021

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Cancer cells and immune cells share something in common: They both love sugar. Sugar is an important nutrient. All cells use sugar as a vital source of energy and building blocks. For immune cells, gobbling up sugar is a good thing, since it means getting enough nutrients to grow and divide for stronger immune responses. But cancer cells use sugar for more nefarious ends.

17 Feb 2021

Genomic test helps identify prostate cancer patients who may benefit from hormone therapy

A commercially available genomic test may help oncologists better determine which patients with recurrent prostate cancer may benefit from hormone therapy, according to new research from the Johns Hopkins Kimmel Cancer Center and 15 other medical centers.

12 Feb 2021

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease.

12 Feb 2021

Bernese researchers create sophisticated lung-on-chip

The lung is a complex organ whose main function is to exchange gases. It is the largest organ in the human body and plays a key role in the oxygenation of all the organs.

10 Feb 2021

Blocking autophagy could help treat certain cancers

Recycling cans and bottles is a good practice. It helps keep the planet clean. The same is true for recycling within cells in the body. Each cell has a way of cleaning out waste in order to regenerate newer, healthier cells. This "cell recycling" is called autophagy.

9 Feb 2021

Intensive BP lowering effective in reducing cardiovascular risk in patients exposed to air pollution

Evidence suggests particulate matter is the air pollutant which poses the greatest threat to global health. Studies have shown that exposure to particulate matter smaller than 2.5 microns is associated with acute and chronic elevations in blood pressure (BP) as well as hypertension.

2 Feb 2021

Surgery News and Research

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Non-circulating memory T cells contribute to chronic transplant rejection

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

New “genome scalpel” can rapidly trim microalgal genomes

Lowering apolipoprotein CIII levels can prevent deleterious effects of a high-fat diet

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Targeted immunotherapy could improve radiotherapy response in cancer cells

Researchers identify gene variant associated with childhood asthma

Study identifies how CTLA-4 blockade can disable suppressive immune cells to aid tumor destruction

Protein imbalance leads to cataract

Study suggests a way to improve immunotherapy by altering immune cells’ access to sugar

Genomic test helps identify prostate cancer patients who may benefit from hormone therapy

New tool reveals potentially risky DNA alterations at site of CRISPR gene repair

Bernese researchers create sophisticated lung-on-chip

Blocking autophagy could help treat certain cancers

Intensive BP lowering effective in reducing cardiovascular risk in patients exposed to air pollution

Targeting glycoprotein could improve response to immune checkpoint therapy

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Synthetic cannabidiol can kill bacteria that causes gonorrhoea

New computational technique accurately differentiates between normal and cancer cells

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