Genetic News and Research

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Researchers prove that drugs designed for bacteria have the potential to act on human cells

Antibiotics used to treat common bacterial infections may potentially be used to treat human illnesses such as cancer, at least theoretically.

27 May 2021

Two components of bacterial CRISPR-Cas immunity system are physically linked

Skoltech scientists have demonstrated that the two components of the bacterial CRISPR-Cas immunity system are physically connected.

27 May 2021

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients

The chemotherapy drug decitabine is commonly used to treat patients with blood cancers, but its response rate is somewhat low. Researchers have now identified why this is the case, opening the door to more personalized cancer therapies for those with these types of cancers, and perhaps further afield.

25 May 2021

Study could help develop peptide siRNA carrier for human oral cancer

MUSC Hollings Cancer Center researchers are exploring the use of peptide carriers for the delivery of small RNA drugs as a novel treatment for cancer. The team's recent work, published online March 19 in the Molecular Therapy - Nucleic Acids journal, lays the foundation for developing a clinically relevant peptide carrier RNAi-based drug treatment strategy for human oral cancer.

25 May 2021

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor.

25 May 2021

Plant-based technology reveals key process in virus infection cycle in dynamic detail

A critical process in the infection cycle of viruses has been revealed for the first time in dynamic detail using pioneering plant-based technology.

25 May 2021

Environmental DNA helps track down species on the move

Many individuals would like to prevent sloughed-off skin and bodily fluids. However, for marine biologists like Cheryl Lewis Ames, Associate Professor of Applied Marine Biology in the Graduate School of Agricultural Science at Tohoku University (Japan), such life remnants have become a magical guide to detecting the unseen.

24 May 2021

New genetic pathway plays a critical role in the ripening of tomatoes

An international research team has found that a genetic pathway known as CHLORAD, also plays a critical role in the ripening of tomatoes.

24 May 2021

Three-dimensional organization of genome is extremely dynamic during gamete formation

Inside the nuclei of cells, the genome is tightly organized (packaged). This three-dimensional (3D) genome organization is basic because it controls gene expression.

21 May 2021

Study shows how mitochondrial function impacts schizophrenia in patients with genetic disorder

Researchers have demonstrated how cell “batteries” play a significant role in whether patients with the chromosomal deletion syndrome acquire schizophrenia.

20 May 2021

Study identifies predictive causal role for specific cell types in type 1 diabetes

Researchers revealed a predicted causative role for certain cell types in type 1 diabetes by examining its genetic foundations.

From UC San Diego 20 May 2021

Study shows that Bubonic Plague had a long-term impact on immune gene expression

A new study shows that the Bubonic Plague has had a long-term impact on immune gene expression.

20 May 2021

Study identifies DNA alterations that underpin brain and cognitive decline in the elderly

According to a new mathematical model published recently in eLife, Alzheimer’s disease has some important similarities with healthy aging.

20 May 2021

High-fat, high-sugar diet reduces intestinal immune cell activity in mice

A team of researchers led by Thaddeus Stappenbeck discovered that a high-fat, high-sugar diet relates to reduced intestinal immune cell activity in mice.

20 May 2021

Study: Turning off molecular switch could help treat melanoma

Melanoma accounts for only about 1% of skin cancers but leads to most of the skin cancer-related deaths.

20 May 2021

New study assesses total economic impact of human genomics

Human genetics and genomifefcs contributed $265 billion to the U.S. economy in 2019 and has the potential to drive significant further growth given major new areas of application, according to a new report issued today by the American Society of Human Genetics (ASHG).

19 May 2021

Wild relatives of modern peanut plants can withstand diseases

The wild relatives of modern peanut plants have the ability to withstand disease in ways that peanut plants can't. The genetic diversity of these wild relatives means that they can shrug off the diseases that kill farmers' peanut crops, but they also produce tiny nuts that are difficult to harvest because they burrow deep in the soil.

From University of Georgia 19 May 2021

Successful class of therapeutics attack and shut down unique and harmful genes

A potential class of therapeutics that uses synthetic nucleic acids to attack and shut down harmful genes while preventing viral spread is gathering momentum.

18 May 2021

Study identifies new epigenetic control pathways in multiple myeloma growth

An international group of researchers from Japan, the United States, and the UK studied the role of the histone demethylase KDM5A in multiple myeloma.

18 May 2021

Refreshers develop new DNA sequencing method

An international research team headed by Michal Hocek of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) and Charles University and Ciara K. O'Sullivan of Universitat Rovira i Virgili (URV) in Spain have developed a novel method for labeling DNA, which in the future can be used for sequencing DNA by means of electrochemical detection.

18 May 2021

Genetic News and Research

Researchers prove that drugs designed for bacteria have the potential to act on human cells

Two components of bacterial CRISPR-Cas immunity system are physically linked

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients

Study could help develop peptide siRNA carrier for human oral cancer

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Plant-based technology reveals key process in virus infection cycle in dynamic detail

Environmental DNA helps track down species on the move

New genetic pathway plays a critical role in the ripening of tomatoes

Three-dimensional organization of genome is extremely dynamic during gamete formation

Study shows how mitochondrial function impacts schizophrenia in patients with genetic disorder

Study identifies predictive causal role for specific cell types in type 1 diabetes

Study shows that Bubonic Plague had a long-term impact on immune gene expression

Study identifies DNA alterations that underpin brain and cognitive decline in the elderly

High-fat, high-sugar diet reduces intestinal immune cell activity in mice

Study: Turning off molecular switch could help treat melanoma

New study assesses total economic impact of human genomics

Wild relatives of modern peanut plants can withstand diseases

Successful class of therapeutics attack and shut down unique and harmful genes

Study identifies new epigenetic control pathways in multiple myeloma growth

Refreshers develop new DNA sequencing method

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