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Breakthrough Discovery in Mitochondrial Recycling Could Impact Health Treatments

Mitochondria, the so-called "powerhouse of the cell," depend on a newly discovered recycling mechanism identified by scientists at The Hospital for Sick Children (SickKids).

22 Aug 2024

UChicago Team Secures $7.4 Million Grant to Study Cellular Adaptation

Cells use a variety of processes to adapt to changes and stressors in their environment, like increased temperature.

21 Aug 2024

New Imaging Technique Offers Clearer View of Brain Function

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue than traditional two-photon microscopy, the new approach could provide a clearer view of how neurons communicate in real time, leading to new insights into brain function and neurological diseases.

16 Aug 2024

Spontaneous Brain Activity Drives Early Neural Circuit Formation

In humans, the process of learning is driven by different groups of cells in the brain firing together. For instance, when the neurons associated with the process of recognizing a dog begin to fire in a coordinated manner in response to the cells that encode the features of a dog -; four legs, fur, a tail, etc. -; a young child will eventually be able to identify dogs going forward. But brain wiring begins before humans are born, before they have experiences or senses like sight to guide this cellular circuitry. How does that happen?

16 Aug 2024

Deep-Learning Model Identifies Parkinson's Disease-Specific Neuroanatomical Features

A deep-learning-based contrastive approach to examine magnetic resonance imaging (MRI) scans from Parkinson’s disease patients.

14 Aug 2024

Advancing Genome Visualization with CRISPR/Cas9 Technology in Live Cells

Understanding the spatiotemporal organization of the genome in the nucleus is crucial for advancing our knowledge of chromatin structure and its functional dynamics in both normal and diseased states.

13 Aug 2024

Noninvasive Ultrasound Method Enables Tracking of Gene Expression in Specific Brain Regions

The ability to alter or prevent the expression of faulty genes in the brain could be leveraged as a powerful therapeutic against neurodegenerative disease. However, the molecular underpinnings of the living brain are still largely inaccessible, hampering progress on such promising therapeutics.

9 Aug 2024

UCL Scientists Uncover New Role of Ribosomes in Protein Folding

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature.

8 Aug 2024

Novel Microscopy Method Revolutionizes Imaging with Reduced Radiation and Faster Results

An international team of scientists, led by Trinity College Dublin, has devised an innovative imaging method using state-of-the-art microscopes that significantly reduces the time and radiation required.

1 Aug 2024

New CRISPR-Based Test Achieves Rapid Detection of Tuberculosis

The rapid detection of Mycobacterium tuberculosis, the etiological agent of tuberculosis.

1 Aug 2024

The Role of Chemical Proteomics in Understanding Small Molecule-Protein Interactions

The various chemical proteomics methods with relevant examples.

31 Jul 2024

Probing Plasma Membrane Dynamics with Cryo-Electron Microscopy

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood.

25 Jul 2024

Novel ATP Imaging System Reveals Insights into Kidney Energy Metabolism

The prevalence of kidney disease has been increasing in Japan, with it now affecting one in eight adults, but developing effective treatment remains a challenge.

24 Jul 2024

High Performance SEM Helps Drive NZ Towards a Smart, Green Future

The existing electron microscopy capabilities have been improved with the installation of a TESCAN CLARA Scanning Electron Microscope (SEM).

24 Jul 2024

Cell Dynamics Drive Dramatic Shape Changes in Insect Development

A small leg might uncover significant insights into how closely related insect species can exhibit dramatic differences in body shape, according to a new study led by researchers at the University of Tokyo.

23 Jul 2024

Researchers Capture Protein Tangle Formation in Real-Time

Protein tangles known as amyloid-beta (A-beta) aggregates are most famously linked to neurodegenerative illnesses like Alzheimer's. Nevertheless, despite its frequent attention, scientists have not been able to fully comprehend how A-beta assembles and disassembles.

22 Jul 2024