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Stress-induced chemoresistance is linked to changes in cellular metabolism

There is a wide range of mechanisms related to chemoresistance, a majority of which are yet to be fully understood.

11 Jun 2020

Microneedle depots effectively deliver stem cells into damaged tissues

Mesenchymal stem cells are multipotent in that they naturally replenish the cell types that build our bone, cartilage and adipose tissues.

10 Jun 2020

Researchers identify genes involved in the development of malignant brain tumor

Researchers have developed a new approach to identify functional mutations and their impact on genes applicable to the development of malignant brain tumors.

10 Jun 2020

Immune system could be 're-trained' to stop attack of healthy cells, study finds

The body's immune system can be re-wired to prevent it from recognizing its own proteins which, when attacked by the body, can cause autoimmune diseases like multiple sclerosis, a significant new study by UK scientists has found.

10 Jun 2020

High sodium intake affects health of gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

10 Jun 2020

KAUST scientists reveal the genetic metronome within malaria parasites

The parasites responsible for malaria seem to march to their own beat.The mystery behind the molecular basis of how these parasites synch their rhythm in replication to the host's clock-driven rhythms has been solved.

10 Jun 2020

Study shows how a network of genes directs trachea and esophagus development

A new study reporting how a network of genes directs the development of the trachea and oesophagus in mice has been published today in eLife.

10 Jun 2020

RDP1 gene regulates the production of pollen grains

An international study has discovered a gene in the plant model Arabidopsis that reduces the number of pollen grains.

9 Jun 2020

Study reveals the relationship between genome folding and cellular functions

According to a study, the 3D structure of the human genome is fundamental to provide a quick and strong inflammatory response.

9 Jun 2020

Researchers identify a promising biomarker to screen stem cell quality

Published recently in the Stem Cells journal, a new study addresses a major issue that has been challenging the human mesenchymal stem cells (hMSCs) therapy.

9 Jun 2020

Study investigates how cancer adapts its metabolism to overcome treatment

Knowing what cancer will do next could lessen the likelihood of it becoming resistant to treatment. A new Canadian study investigates how cancer adapts its metabolism to potentially overcome therapies still in development.

From University of Toronto 9 Jun 2020

Study reveals new insight on vaccines and antimicrobials

Bacteria are known to be versatile living organisms capable of colonizing a wide variety of tissues, hosts, or environments inside a host.

9 Jun 2020

Genome rewiring could help explain evolution of multi-cellular organisms

InsideOutBio expert Dr Alan Herbert has explained a pioneering research in a paper recently published online by the Royal Society Open Science journal.

9 Jun 2020

Study shows how a fat cell's immune response exacerbates obesity

When obesity occurs, a person's own fat cells can set off a complex inflammatory chain reaction that can further disrupt metabolism and weaken immune response--potentially placing people at higher risk of poor outcomes from a variety of diseases and infections, including COVID-19.

8 Jun 2020

Study uncovers new risk genes for problematic alcohol use

Do you have what is known as problematic alcohol use? Then statistically you will also be particularly genetically predisposed to develop e.g. depression and insomnia. And to become dependent on drugs and tobacco. This is shown by a new international study in which researchers from iPSYCH are involved.

8 Jun 2020

A synthetic microbial system can determine location of origin for objects

Every year, an estimated 48 million Americans get sick from foodborne illnesses, resulting in some 128,000 hospitalizations and 3,000 deaths, according to the U.S. Centers for Disease Control and Prevention.

5 Jun 2020

Single-cell-resolution technologies help map brain regions in humans and primates

Using the single-cell-resolution transcriptomics technologies, researchers have performed a large-scale analysis of gene expression in 33 different brain regions of chimpanzees, bonobos, macaques, and humans, and successfully generated a map of the various brain regions with their particular cell structures.

5 Jun 2020