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Human genome may explain the neonatal origins of immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

29 Jul 2020

Study sheds new light on core regulatory networks that govern cell types in vertebrates

The FANTOM Consortium has shed new light into the main regulatory networks that govern the types of cells found in different vertebrate species.

29 Jul 2020

New technology helps visualize entire genome at molecular resolution

Scientists from Harvard University, CNAG, and CRG have demonstrated a pioneering technology that helps observe hundreds of genomes under the microscope.

29 Jul 2020

Study pinpoints the miRNA that promotes hair follicle growth

A research team from North Carolina State University has discovered a microRNA, or miRNA, that could make hairs to grow again.

29 Jul 2020

A novel approach to identify cancer targets using 'synthetic lethality'

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells.

28 Jul 2020

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

28 Jul 2020

Artificial intelligence-based process can help design novel proteins

Proteins are known to perform complex tasks and catalyze chemical reactions, making them crucial for cell survival.

27 Jul 2020

Research identifies TLR7 gene that predisposes individuals to severe COVID-19

Current observations suggest that the coronavirus SARS-CoV-2 causes severe symptoms mainly in elderly patients with chronic disease.

27 Jul 2020

Computational tool can help study APA mechanism that regulates gene expression

Scientists keen on solving the regulation of genes implicated in human health and disease are widening their horizons by closely APA.

27 Jul 2020

Study shows how cancer develops resistance to chemotherapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back.

24 Jul 2020

Study shows KBTBD2 gene plays a key role in regulating insulin sensitivity

Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows.

24 Jul 2020

Epigenomic data can help characterize genes that play key role in cancer progression

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

From Massachusetts Institute of Technology (MIT) 24 Jul 2020

Researchers identify the role of calcium channel subunits in synapse development

The ability of the human brain to process and store information is determined to a large extent by the connectivity between nerve cells. Chemical synapses are very important in this context as they constitute the interface for the transmission of information between individual nerve cells.

23 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Humans are mutating SARS-CoV-2, but natural selection enables the virus to bounce back

Scientists investigating the evolution of the virus that causes Covid19 say that its mutation seems to be directed by human proteins that degrade it, but natural selection of the virus enables it to bounce back. The findings could help in the design of vaccines against the virus.

From University of Bath 23 Jul 2020

Infectious bacteria can produce genetic variants among siblings, study finds

A research team from the University of Tübingen and the German Center for Infection Research is investigating how pathogens influence the immune response of their host with genetic variation.

23 Jul 2020

Fusion protein found to effective at treating pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is an insidious disease. Symptoms may begin slowly, and even before they appear, extensive damage has caused the obstruction of small arteries leading to increased blood pressure in the lungs.

22 Jul 2020

Boosting metabolic resources in the brain could be a way to slow neurodegeneration

Researchers at Vanderbilt University Medical Center have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy.

From Vanderbilt University 22 Jul 2020

Researchers identify a potential biomarker of aging

The skin is the only organ that shows age more profoundly. While researchers have hypothesized about the ravages of time on skin and also the epidermal stem cells that undergo differentiation to restore the external layer of the skin, no suitable method is available to assess their aging at the molecular level.

22 Jul 2020

Novel genetic measure could improve screening for osteoporosis

An international team of scientists has developed a novel genetic measure that could dramatically improve how doctors assess the risk of sustaining a fracture due to osteoporosis or fragility.

22 Jul 2020

Genes News and Research

Human genome may explain the neonatal origins of immune and inflammatory diseases

Study sheds new light on core regulatory networks that govern cell types in vertebrates

New technology helps visualize entire genome at molecular resolution

Study pinpoints the miRNA that promotes hair follicle growth

A novel approach to identify cancer targets using 'synthetic lethality'

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

Artificial intelligence-based process can help design novel proteins

Research identifies TLR7 gene that predisposes individuals to severe COVID-19

Computational tool can help study APA mechanism that regulates gene expression

Study shows how cancer develops resistance to chemotherapy

Study shows KBTBD2 gene plays a key role in regulating insulin sensitivity

Epigenomic data can help characterize genes that play key role in cancer progression

Researchers identify the role of calcium channel subunits in synapse development

New startup launched to overcome the challenge of delivering next-generation therapeutics

Humans are mutating SARS-CoV-2, but natural selection enables the virus to bounce back

Infectious bacteria can produce genetic variants among siblings, study finds

Fusion protein found to effective at treating pulmonary arterial hypertension

Boosting metabolic resources in the brain could be a way to slow neurodegeneration

Researchers identify a potential biomarker of aging

Novel genetic measure could improve screening for osteoporosis

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