Liver News and Research

RSS

Study Identifies Adipogenin as Crucial Driver of Lipid Droplet Formation

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets – a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows.

27 Nov 2025

Breakthrough Reveals How Immune Cells Orchestrate Pathological Scarring

Researchers at the University of Arizona uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead to organ failure and disfigurement.

26 Nov 2025

Discovery Offers a Potential Way to Boost Tissue Resident Memory T Cell Numbers

We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the body's first responders to disease.

24 Nov 2025

CRISPR Gene Editing Reverses Chemotherapy Resistance in Lung Cancer

In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in lung cancer. The approach restores drug sensitivity and slows tumor growth.

18 Nov 2025

Cellarity's AI Model Predicts Drug Induced Liver Injury

Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in Nature Communications, which describes a novel framework for the prediction and characterization of drug-induced liver injury (DILI), along with open-source posting of the model and validation data.

14 Nov 2025

Animal Testing to Be Phased Out Faster as UK Unveils Roadmap for Alternative Methods

Animal testing in science is set to be phased out faster under a new plan to deliver on the government’s manifesto commitment, unveiled by Science Minister Lord Vallance today (Tuesday 11 November).

13 Nov 2025

Long-Term Analysis Provides a Novel Look at Harmful Algal Blooms

A long-term analysis shows that a major Oregon reservoir abruptly swapped one type of toxic algae for another midway through the 12-year study period, absent any obvious cause.

12 Nov 2025

‘Forever chemicals’ build up in British Columbia sea otters

PFAS contamination in British Columbia sea otters underscores urban pollution's effects on marine life and the importance of long-term ecological monitoring.

12 Nov 2025

3D Ultrasound That Sees Entire Organ Blood Flow in Real Time

This study presents a multi-lens ultrasound system that offers tenfold higher resolution for whole-organ imaging, improving microvascular network visualization.

6 Nov 2025

TRF1 Knockout Mice Exhibit Healthier Metabolic States Without Telomere Shortening

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles."

28 Oct 2025

Mitochondria and Lysosomes Orchestrate Metabolic States of Regulatory T Cells

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system.

27 Oct 2025

Understanding the Ecological Trap Threatening Winter-Ready Species

Even as autumn days grow shorter, a warming climate means Ohio winters aren't as cold as they were just a few decades ago, according to National Oceanic and Atmospheric Administration data.

10 Oct 2025

Breakthrough in Understanding How Tick-Borne Encephalitis Virus Infects Human Brain Cells

The protein on human cells that tick-borne encephalitis virus (TBEV) uses for infection has now been identified-a major step toward understanding how TBEV causes neurological disease and for developing antiviral drugs.

3 Oct 2025

PNPLA3 Gene Variant Linked to Liver Injury After Chemotherapy in Colorectal Cancer Patients

A new international study led by Mayo Clinic researchers has identified a genetic factor that may explain why some patients with colorectal cancer that has spread to the liver experience more severe liver damage after chemotherapy.

30 Sep 2025

PANoptosis Could Revolutionize Liver Cancer Diagnostics and Treatment

Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the deadliest cancers, driven by high recurrence and resistance to therapy.

22 Sep 2025

Metastatic Lung Cancer Cells Cozy Up to Neurons and Form Synapses

Small cell lung cancer cells that metastasize to the brain cozy up to neurons and form working electrical connections, called synapses, according to an upcoming study led by Stanford Medicine researchers.

11 Sep 2025

Aptamer Group Introduces Novel Biomarker Discovery Service

Aptamer Group plc, the leading developer of next-generation synthetic binders delivering innovation to the life science industry, today announced the launch of its biomarker discovery service, offering researchers in pharmaceutical, biotechnology, and diagnostic development an innovative approach to identify and validate new disease markers.

28 Aug 2025