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Study Highlights Cellular and Molecular Characteristics of Senescent Ocular Surface Cells

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 18, entitled, "Gene expression signatures of human senescent corneal and conjunctival epithelial cells."

4 Oct 2023

Research Offers a Promising Avenue for Improving T-Cell-Based Cancer Therapies

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

4 Oct 2023

New Computational Approach Efficiently Identifies Optimal Genetic Perturbations

A strategy for cellular reprogramming involves using targeted genetic interventions to engineer a cell into a new state.

3 Oct 2023

Wildling Mice With High Microbial Exposure can Develop Allergies

The notion that some level of microbial exposure might reduce our risk of developing allergies has arisen over the last few decades and has been termed the hygiene hypothesis.

3 Oct 2023

Improving the Efficiency of Gene Delivery to the Brain

Researchers from Rice University conducted tests to assess the safety and feasibility of gene delivery to various regions of the brain using a noninvasive technique based on ultrasound in rodents.

28 Sep 2023

Unraveling the Link Between Chromosomal Instability and Cancer Spread

Chromosomal instability is a phenomenon marked by rapid alterations in the count and configuration of chromosomes during cell division. This occurrence is prevalent in solid tumors and is closely associated with the aggressive dissemination of cancer, known as metastasis.

27 Sep 2023

Using Genetic Engineering to Facilitate Mutualistic Relationships Between Plants and Nitrogen-Fixing Microbes

Nitrogen is an essential nutrient for plant growth, but the overuse of synthetic nitrogen fertilizers in agriculture is not sustainable.

27 Sep 2023

Scientists Develop Molecular Radar to Detect Active Cullin-RING Ligases

Our cells have a fleet of 300 molecular machines, called cullin-RING ligases, or "CRLs" for short, that each is capable of triggering destruction of specific proteins for the well-being of our cells.

27 Sep 2023

Mathematical Recipe for Sperm Tail Motion Discovered

Patterns of chemical interactions are thought to create patterns in nature such as stripes and spots. This new study shows that the mathematical basis of these patterns also governs how the sperm tail moves.

27 Sep 2023

Ultra-High Field 7 Tesla MRI Helps Better Understand How Light Stimulates the Brain

New research conducted at the University of Liège, using ultra-high field 7 Tesla MRI, provides a better understanding of how light stimulates our brain and could provide new insights into how it works.

25 Sep 2023

Breakthrough Method Uncovers MicroRNA Tasks in Single Cells

Scientists at Stockholm University and SciLifeLab have achieved a groundbreaking feat by creating the first technique capable of unveiling the specific functions that microRNAs carry out within individual cells.

22 Sep 2023

Ribo-seq Optimization to Gain Insights into Protein Production

Ribosome profiling, a gene sequencing approach, has increased the understanding of the human genome by uncovering previously undiscovered protein-coding regions.

22 Sep 2023

New Method That Genetically Modifies Individual Cells in Animals

Researchers at ETH Zurich have created a technique that enables them to genetically alter every animal cell in a unique way.

22 Sep 2023

How Scientists are Using iPSCs to Develop New Therapies

In 1998, scientists reported being able to derive cells from human embryos that could develop into almost any cell in the body. In 2007, the field took a huge leap when scientists discovered they could reprogram human adult skin cells to act like these embryonic stem cells.

20 Sep 2023

How Whole Orchard Recycling can Benefit Microbial Nitrogen in Soils

What happens to orchards when they’ve reached the end of their lifespan and are no longer producing crops? Conventionally, orchards are burned. However, concerns about biomass burning and air quality have led to an alternative practice known as whole orchard recycling.

19 Sep 2023

Fruit Fly Study Reveals New Insights into Exercise and Cold Tolerance

As the northern hemisphere experiences shorter and colder days, individuals who prefer morning workouts may encounter increased difficulty in getting up and running.

19 Sep 2023

Oregon State Receives $7.5M Grant to Modernize Zebrafish Research Lab

Oregon State University has received a $7.5 million National Institutes of Health grant to modernize a lab focused on using zebrafish to address pressing human health challenges.

19 Sep 2023

Pre-Targeted Radioimmunotherapy System Cures Fatal Ovarian Cancer in Preclinical Study

A new 225Ac-DOTA-based pre-targeted radioimmunotherapy (PRIT) system has been shown to cure a highly lethal form of advanced intraperitoneal ovarian cancer in a preclinical setting with minimal side effects.

19 Sep 2023

Scientists Uncover New Genetic Insights into Staphylococcus Aureus

New genetic insights into Staphylococcus aureus have been discovered by Australian researchers, showing what makes the bacteria so hazardous when it enters the bloodstream.

13 Sep 2023

Genomic Surveillance Finds Malaria-Causing Parasites Resistant to Treatments

Scientists have discovered new strains of malaria-causing parasites in Ethiopia that are both resistant to current treatments and evade detection by common diagnostic tests—a development that could increase malaria cases and deaths while making eradicating the disease even more difficult.

12 Sep 2023