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Study opens new avenues for therapies against Charcot-Marie-Tooth disease

CMT, a rare hereditary condition, commences when genetic changes interrupt the transmission of nerve signals from the brain to the muscles of the extremities, specifically those of the lower limbs.

16 Sep 2021

Researchers infer chemical steps involved in methylthiolation of tRNAs

Recent research revealed the chemical steps in a vital cellular modification mechanism that inserts a chemical tag to certain RNAs. Interference of this process in humans can result in cancers, diabetes, and neuronal diseases.

From Penn State University 16 Sep 2021

Researchers reveal why nerve cell’s protein production slows down in CMT patients

A team led by MDC researcher Marina Chekulaeva has figured out why protein production slows down in the nerve cells of people suffering from Charcot-Marie-Tooth disease. This discovery could lead to a new therapeutic approach, the scientists report in the journal "Nucleic Acids Research".

16 Sep 2021

Aptamers for Targeting SARS-CoV-2 Proteins

AMSBIO has further expanded its product range to help in the fight against COVID-19 with the introduction of a new range of aptamers targeting SARS-CoV-2 proteins to aid development of new kits and assays.

From AMS Biotechnology 15 Sep 2021

Scientists develop a technique for reconstructing whole genomes on a personal computer

Scientists at the Massachusetts Institute of Technology and the Institut Pasteur in France have developed a technique for reconstructing whole genomes, including the human genome, on a personal computer.

From Massachusetts Institute of Technology (MIT) 15 Sep 2021

Scientists devise a strategy to enhance anti-tumor immunity

A synthetic molecular code exhibits the potential of enhancing the response of certain cancer patients to immunotherapy treatments.

15 Sep 2021

Scientists discover how thousands of tiny anchors help the cells stay put and resist disruptions

Most of the cells in our bodies – be they bone, muscle or pancreas cells – are locked into the right place with the help of tiny anchors (called 'focal adhesions').

From The University of New South Wales (UNSW) 14 Sep 2021

Study unravels the DNA repair mechanism by enzymes

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Study reveals how autoimmune antibodies can predict severe cases of COVID-19

The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows.

From New York University (NYU) 9 Sep 2021

New technology harnesses a natural feature of therapeutic antibodies to attack blood cancer cells

Researchers at the University of Southampton and biopharma company UCB have found a way to enhance the natural ability of therapeutic antibodies to attack blood cancer cells using part of the human immune system known as the complement cascade, opening the way for a potential new class of treatments.

8 Sep 2021

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

A compact CRISPR-Cas system, known as CasMINI, can be employed for gene-therapy and cell-engineering applications as it is easier to deliver into cells.

7 Sep 2021

Study provides deep insights into the association between genes and diseases

Scientists examined genomic data from more than 30,000 individuals and unraveled thousands of new regulatory regions that regulate disease-linked genes.

7 Sep 2021

Miniature CRISPR-Cas system expands applicability and implications further

For the first time, Stanford researchers have miniaturized CRISPR for mammalian gene editing, which magnifies the scope of CRISPR technology.

3 Sep 2021

Research shows how dendrimers avoid detection by the immune system

Tiny synthetic particles known as dendrimers have been shown to avoid detection by our immune system and so could be used to develop a new system to deliver drugs into the body without triggering a reaction.

3 Sep 2021

Study: Fat tissue of older mice lose the ability to restore body heat in cold temperatures

The evolution of humans has given them a level of protection from the risk of cold temperature with the ability to generate heat from fat stored in the body.

3 Sep 2021

Study reveals possibilities to disrupt dynamics and halt SARS-CoV-2 transmission

Researchers have simulated the transition of the SARS-CoV-2 spike protein structure from the time it recognizes the host cell to its entry into the cell.

2 Sep 2021

New approach to enhance cell-free biosynthesis with engineered yeast extracts

Think of cells as tiny factories: within their walls they have both the machinery to make products such as proteins, and the mechanisms for maintenance to keep processes running smoothly.

31 Aug 2021

Researchers fabricate 3D-integrated nanopores to detect single DNA molecules

Detecting DNA from a single cell is vital for the identification of genetic disorders and diseases.

From Osaka University 31 Aug 2021

Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.

From UC San Diego 20 Aug 2021

New method can efficiently convert plant matter into high-value bioproducts

A team of scientists at the University of Illinois Urbana-Champaign developed a bioprocess using engineered yeast that completely and efficiently converted plant matter consisting of acetate and xylose into high-value bioproducts.

18 Aug 2021

Molecule News and Research

Study opens new avenues for therapies against Charcot-Marie-Tooth disease

Researchers infer chemical steps involved in methylthiolation of tRNAs

Researchers reveal why nerve cell’s protein production slows down in CMT patients

Aptamers for Targeting SARS-CoV-2 Proteins

Scientists develop a technique for reconstructing whole genomes on a personal computer

Scientists devise a strategy to enhance anti-tumor immunity

Scientists discover how thousands of tiny anchors help the cells stay put and resist disruptions

Study unravels the DNA repair mechanism by enzymes

Study reveals how autoimmune antibodies can predict severe cases of COVID-19

New technology harnesses a natural feature of therapeutic antibodies to attack blood cancer cells

Study explores the efficiency of CasMINI, an engineered CRISPR-Cas system

Study provides deep insights into the association between genes and diseases

Miniature CRISPR-Cas system expands applicability and implications further

Research shows how dendrimers avoid detection by the immune system

Study: Fat tissue of older mice lose the ability to restore body heat in cold temperatures

Study reveals possibilities to disrupt dynamics and halt SARS-CoV-2 transmission

New approach to enhance cell-free biosynthesis with engineered yeast extracts

Researchers fabricate 3D-integrated nanopores to detect single DNA molecules

Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

New method can efficiently convert plant matter into high-value bioproducts

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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