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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Parkinson’s Gene Mutation Blocks Vital Neuroprotective Signals

GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a shared pathogenic pathway.

7 Aug 2025

Uncovering How Cells Precisely Control Protein Production

It's known as biology's central dogma: All living organisms' genetic information is stored in DNA, which is transcribed into RNA, which is translated into proteins that perform nearly all essential tasks in a cell.

6 Aug 2025

New Computational Tool Reveals How Long Non-Coding RNAs Control Gene Expression

Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed.

6 Aug 2025

Small Changes in Brain Enzyme May Have Shaped Modern Human Behavior

The evolutionary success of our species may have hinged on minute changes to our brain biochemistry after we diverged from the lineage leading to Neanderthals and Denisovans about half a million years ago.

5 Aug 2025

AI Tool Accelerates Hunt for Elusive Genome‐Encoded Microproteins

Proteins sustain life as we know it, serving many important structural and functional roles throughout the body.

1 Aug 2025

Mitochondrial Gene Found to Regulate Wood Formation in Poplar

Mitochondria are widely known as the "powerhouses" of the cell, generating the energy needed for life. But in plants, their role goes far beyond metabolism.

31 Jul 2025

Blocking TG2 Could Help Immune Cells Attack Ovarian Tumors

The study reveals TG2's role in ovarian cancer metastasis, suggesting that its inhibition could re-educate the immune system for better anti-tumor efficacy.

30 Jul 2025

scLT-kit Empowers Single-Cell Lineage Tracing with Automated Analysis

Researchers at Tsinghua University have released a novel Python toolkit, scLT-kit, which automates the processing and analysis of single-cell lineage tracing data, delivering clear insights into how individual cells develop, differentiate, and respond to treatments.

29 Jul 2025

Multi-Omics Approaches Reveal New Insights into Colorectal Cancer Liver Metastasis

Colorectal cancer is among the most prevalent and lethal malignancies worldwide, with liver metastases occurring in nearly one-third of patients and accounting for a major share of cancer-related deaths.

29 Jul 2025

Rewriting rRNA Alters the Architecture of the Nucleolus

Ribosomes carry out the cell's most essential function-translating genetic information into proteins.

28 Jul 2025

New Computer Program Mimics Human and Animal Cell Behavior

Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body.

28 Jul 2025

Gene Editing Offers New Hope to Stop Malaria Transmission

Mosquitoes kill more people each year than any other animal. In 2023, the blood-sucking insects infected a reported 263 million people with malaria, leading to nearly 600,000 deaths, 80% of which were children.

24 Jul 2025

Improved Agrobacterium Strains Enhance Plant Genetic Engineering Efficiency

These mutations improve biocontainment, transformation stability, and overall performance in genetic engineering of plants.

22 Jul 2025

New Chemical Tool Protects Mitochondrial DNA from Environmental Damage

When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration, and chronic inflammation.

22 Jul 2025

mRNA Vaccine Supercharges Immunotherapy Against Cancer

An experimental mRNA vaccine improved the tumor-fighting benefits of immunotherapy in a mouse model study, bringing researchers one step closer to their aim of generating a universal vaccination to “wake up” the immune system against cancer.

21 Jul 2025

New Research Reveals Key Protein Behind Plant Heat Tolerance

While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive extreme heat? It's a question many have wondered-and now, science has an answer.

15 Jul 2025

Elegen and Nutcracker Therapeutics to Pilot First Fully Cell-Free Manufacturing Process for RNA-based Personalized Cancer Therapeutics

Elegen, a global leader in next-generation DNA manufacturing, and Nutcracker Therapeutics, a global leader in next-generation RNA design and manufacturing, today announced the launch of a pilot program to demonstrate the industry's first fully synthetic, cell-free manufacturing platform for RNA-based personalized cancer therapeutics (PCTs).

From Elegen 15 Jul 2025