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Genomic-First Approach Offers Potential for Earlier Diagnosis of Rare Disorders

A "genomic-first" approach to screening for rare genetic disorders -identifying specific genetic variants and then studying associated traits and symptoms - can identify these conditions earlier and more frequently than standard genetic testing driven by clinical symptoms, a Geisinger study found.

8 Oct 2025

Living Biofilms Act as Natural Batteries to Degrade Antibiotics at Night

Researchers have unveiled a surprising new way that soil microbes can use sunlight energy - even after the lights go out.

8 Oct 2025

Structural Variation and Resistance Gene Clusters Drive Disease Defense in Wild Grapes

Grapes are a cornerstone of global agriculture and the foundation of the wine and table grape industries.

8 Oct 2025

Multiple Genetic Changes Play Key Role in the Development of Complex Disorders

The genetic roots of a disease or disorder do not always grow into clear cut, easily diagnosed clinical features.

8 Oct 2025

Measuring KIF1A Motor Protein Force with DNA Nanosprings

Cells all require the transport of materials to maintain their function. In nerve cells, a tiny motor made of protein called KIF1A is responsible for that.

8 Oct 2025

New Computer-Driven Strategy Reveals How Membrane Proteins Maintain Stability

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring cells stick together.

8 Oct 2025

Studies Uncover PAR2 Receptor’s Role in Gut Inflammation and Pain

Abdominal pain is common in a variety of digestive diseases, including inflammatory bowel disease and irritable bowel syndrome.

8 Oct 2025

Antibody 04_A06 Neutralizes Nearly All Tested HIV Variants in Laboratory Studies

A Cologne-led research team has discovered the antibody 04_A06, which neutralizes the human immunodeficiency virus (HIV) in almost all tested variants in vitro and even overcomes typical resistance mechanisms.

7 Oct 2025

Intergenerational Transmission of Exercise Benefits Mediated by Sperm MicroRNAs

n a recent study published in Cell Metabolism, a collaborative research team led by Chen-Yu Zhang, Xi Chen, and Di-Jun Chen from Nanjing University, together with Tao Zhang from Nanjing Medical University, reported groundbreaking findings in their paper entitled "Paternal exercise confers endurance capacity to offspring through sperm microRNAs."

7 Oct 2025

Study Reveals Tissue-Specific DNA Patterns Used by HIV to Evade Detection

Researchers at Western University and the University of Calgary have discovered how HIV hides in different parts of the body by embedding itself into the DNA of cells in a tissue-specific manner, offering new insights into why the virus is so difficult to eliminate and cure – even decades after infection and treatment.

7 Oct 2025

Wasatch Biolabs Expands Service Portfolio with Oxford Nanopore Assays in Pharmacogenomics, Telomere Sequencing, and mRNA Vaccine Quality Control

Wasatch BioLabs (WBL), a Renew Biotechnologies subsidiary, and the largest U.S. sequencing service provider dedicated exclusively to long-read sequencing, today announced the addition of three Oxford Nanopore-developed research-use-only (RUO) assays to its service portfolio: a Pharmacogenomics (PgX) panel, Telomere Sequencing, and mRNA Vaccine Quality Control.

7 Oct 2025

EZH2 Inhibition Restores Order in Cancer Cell Division and Reduces Metastasis

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from spreading.

6 Oct 2025

New NMR Method Reveals How Enzymes Move During Reactions

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex molecular machinery like enzymes move while they help catalyze reactions.

6 Oct 2025

Golden Broccoli Aptamer Enables Real-Time Measurement of Glycine

The amino acid glycine is an important neurotransmitter that regulates memory, reflex and brain development, and it may also be a biomarker for bacterial virulence.

6 Oct 2025

New Genetic Map of Human Metabolism Reveals How Genes Influence Health and Disease

A recent study published in Nature Genetics developed the largest genetic map of human metabolism, giving new insights into the role of metabolites in health and disease and providing a framework for future research.

6 Oct 2025

Understanding the Impact of Phytohormones on Plant Adaptation in Extreme Environments

Which plant hormones are critical in responding to drought conditions? How do plant hormone responses adjust to environmental changes?

3 Oct 2025

New Technology can Map RNA-Protein Interactions Inside Human Cells

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells - an achievement that could offer new strategies for treating diseases ranging from cancer to Alzheimer's.

3 Oct 2025