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Unraveling How E. histolytica Kills Cells and Evades the Immune System

Understanding how E. histolytica attacks human cells and evades immunity is crucial for developing effective treatments and vaccines against this parasite.

13 May 2025

AI Designs Synthetic DNA to Control Gene Expression in Mammalian Cells

A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

10 May 2025

Study Reveals T Cell Plasticity as a Key Driver of Systemic Autoimmunity

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

5 May 2025

Dr. Jeremy Poschmann’s data-driven approach to immune profiling and translational science

Dr. Jeremy Poschmann discusses data-driven approaches in genomics, revealing how immune profiling can predict disease risk and improve patient outcomes.

1 May 2025

Single DNA Mutation Dysregulates Key Tumor-Suppressing Pathways in Blood Cancer

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer treatment.

30 Apr 2025

New Drug Combo Shows Promise Against Aggressive Leukemia in Landmark Study

A novel drug combination targeting LSD1 and GSK3 shows promise in treating acute myeloid leukemia by promoting cell differentiation and reducing tumor growth.

28 Apr 2025

Unraveling the Role of Long Noncoding RNAs in the Tumor Microenvironment

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to influence tumorigenesis, progression, and metastasis.

25 Apr 2025

DNA Organization Offers Clues for Advancing Stem Cell Therapy

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power. The researchers demonstrate in a paper published in the journal Genes & Development that these cells rely on a group of helper proteins called histone chaperones — organizers or guides known to help package our two-meter-long genome when cells need to divide or switch on specific genes.

22 Apr 2025

New Blood Test Could Revolutionize Alzheimer’s Diagnosis

Research confirms the Lumipulse serum p-tau217 assay's effectiveness in diagnosing Alzheimer's, paving the way for accessible blood-based testing in healthcare.

18 Apr 2025

Genetic Variants Offer Clues to Targeted Asthma Treatments

Genome wide association studies (GWAS) have identified hundreds of genome regions containing thousands of genetic variants associated with asthma, but it's still not clear which variants have an actual causal link to the disease.

11 Apr 2025

Rapid Growth of Blood Cancer Driven by a Single Genetic ‘HIT’

A new study has unveiled when chronic myeloid leukaemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows.

10 Apr 2025

QRICH1 Protein Found to Control T Cell Activation in Cancer and Autoimmune Diseases

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025