Cas9 News and Research

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RNA-Based Molecular Switch Enhances Disease Resistance in Pears

In recent years, scientists have uncovered the remarkable regulatory power of long non-coding RNAs (lncRNAs) - RNA molecules once dismissed as "genetic dark matter."

24 Oct 2025

Molecular Brake SlKNU Regulates Flower Formation and Fruit Development in Tomato

Floral meristems (FMs) are small clusters of stem cells that orchestrate flower formation and ultimately determine the size and structure of the fruit.

17 Oct 2025

Research Reveals Transcriptional Mechanism Behind Salt Tolerance in Watermelon

High soil salinity disrupts water absorption, ion balance, and photosynthesis in plants, leading to growth inhibition and yield loss.

16 Oct 2025

Acidic Tumor Environment Found to Rewire Cancer Cell Metabolism

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

10 Oct 2025

SHAT2 Transcription Factor Influences Rice Seed Shattering and Grain Traits

In natural ecosystems, the timely abscission of seeds in wild plants is a crucial adaptive trait that contributes to reproductive success, population renewal, and colony expansion.

22 Sep 2025

Innovative Alternative Gene Editing Approach May Be Safer Than CRISPR

Genetic editing holds promise to treat incurable diseases, but the most popular method - CRISPR - sometimes does more harm than good.

22 Sep 2025

Editing SlVI Gene Enhances Sugar Content and Disease Resistance in Tomato Fruit

Tomato fruit development relies on complex sugar metabolism, including the conversion of stored starch into sucrose, glucose, and fructose.

22 Sep 2025

Modified Cas9 Proteins Dramatically Lower Error Rates in Prime Editing

A genome-editing technique known as prime editing holds potential for treating many diseases by transforming faulty genes into functional ones.

18 Sep 2025

Loss of Zfy Genes Explains Why Some Sperm Fail

A study at the University of Hawaiʻi at Mānoa by researchers from the John A. Burns School of Medicine (JABSOM) found that losing a crucial male fertility gene causes infertility and alters the expression of hundreds of other genes.

17 Sep 2025

CRISPR Breakthrough Makes Cacao Plants More Resistant To Deadly Disease

This study shows CRISPR-Cas9 modifications to the TcNPR3 gene in cacao reduce Phytophthora susceptibility, supporting eco-friendly agricultural practices.

17 Sep 2025

Engineered Base Editor Corrects ACTA2 Mutation in Rare Childhood Disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

13 Sep 2025

New Method Discovers Genetic Switches More Quickly

Researchers led by Dubravka Vučićević at the Max Delbrück Center have developed a new method for discovering how DNA controls genes. Published in “Cell Genomics,” their technique can reveal the genetic “switches” that regulate important genes more quickly than existing methods.

10 Sep 2025