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Research Reveals Molecular Link Between Matrix Protein Motifs and Ameloblast Organization

Tooth enamel looks simple from the outside and consists of a hard, smooth surface built to withstand years of wear.

12 Sep 2026

Human Embryos Repair Single-Strand DNA Damage Reliably but Fail at Double-Strand Breaks

Although DNA repair is one of the fundamental processes required for normal human embryonic development, little has been known about how it operates during the earliest stages of development.

10 Sep 2026

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one specialized for cytokine production and the other for direct killing.

7 Sep 2026

AI-Designed Protein Vehicle Enables Lower RNA Dosing While Maximizing Therapeutic Protein Expression

Researchers at Helmholtz Munich and TUM have developed Synthetic Transfer Vehicles (STVs), an entirely new class of RNA transporters. To do so, they combined naturally occurring protein building blocks with synthetic protein structures designed using generative AI.

3 Sep 2026

Single-Gene Edits Fall Short of Stopping Immune Rejection in Beta Cell Grafts

In people with type 1 diabetes, the immune system mistakenly destroys the pancreatic beta cells responsible for producing insulin. Patients therefore require lifelong insulin therapy to regulate their blood glucose levels.

21 Aug 2026

Method Reveals How Influenza A Takes Over Host Cell Machinery

A new study identifies influenza A virus interactions with human proteins, uncovering mechanisms of paraspeckle disruption and insights for antiviral development.

4 Aug 2026

Structure-Guided Protein Engineering Unlocks Safer Methods for Gene Therapy

A joint research team led by Professor Daesik Kim (Department of Medicine, Sungkyunkwan University), along with Professor Yong-Sub Kim (University of Ulsan College of Medicine) and Professor Jae-Hyun Park (Sungkyunkwan University School of Medicine), has announced the development of 'OpenABE' (Open Adenine Base Editor).

31 Jul 2026

CRISPR Technology Enables First Successful Gene Editing in Biting Midges

Scientists have successfully edited the genome of biting midges, opening the door to new research on how these insects transmit disease.

20 Jul 2026

New Method Derives Red Blood Cell-Like Cells From Canine iPSCs

Blood transfusions are crucial in human and veterinary medicine, yet human blood reserves are in constant need of donors while blood bank systems in veterinary care are nearly non-existent.

20 Jul 2026

Single Nucleus RNA Sequencing Decodes Tomato Plant Early Stage Development

Seedling emergence is one of the most vulnerable stages in plant life. In darkness, seedlings undergo skotomorphogenesis, forming elongated hypocotyls and curved apical hooks that protect the shoot tip as it pushes through soil.

29 Jun 2026

Biologists Capture Snapshot of Evolutionary Transition in Y Chromosome Gene

The study, published in Volume 153, Issue 9 of the journal Development on May 14, 2026, by The Company of Biologists, is the first to precisely map endogenous UTY occupancy across the human genome and demonstrate that UTY remains functionally involved in transcriptional regulation during early human development.

8 Jun 2026

Antibody-Directed Xenophagy Pathway Blocks Intracellular Infections From Spreading

Scientists have revealed the process by which cells can internally digest bacteria and viruses.

5 Jun 2026

New Gene-Editing Strategy Ensures Quality Control in Stem Cell Therapies

A team of researchers led by Luigi Naldini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) has developed a new strategy to significantly improve the precision and safety of CRISPR-Cas9 gene editing.

3 Jun 2026

Cornell Researchers Develop Safer CRISPR Technique Using DNA Nicks

Researchers at Cornell University have developed a safer and more precise way to study how genes function in living tissues by refining a recently developed CRISPR-based genetic technique in fruit flies, enabling researchers to better study how genes contribute to development and disease.

28 May 2026

Essential Keratin Guides Embryonic Cell Movement in Developing Zebrafish

Hair, nails, and horns, all made up of keratin, are some of the hardest and most resilient structures in animals. Inside zebrafish cells, keratin plays a distinct role, giving them the strength they need to move together as a coherent tissue while modulating the driving forces behind their movement during early development. But what happens when keratin is missing?

22 May 2026

Prime Assembly Enables Precise Insertion of Large DNA Segments Into the Genome

Researchers at UMass Chan Medical School have developed a gene editing technology that allows for the precise and efficient insertion of very large DNA segments into the human genome.

13 May 2026

New CRISPR System Destroys Diseased Cells With High Precision

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched.

8 May 2026

Breakthrough CRISPR Discovery Enables Selective Destruction of Cancerous Cells

Among the challenges in treating disease, including cancer, is wiping out malignancies, infection, contaminants or other pathologies, without destroying healthy tissue.

7 May 2026

Regulatory Genetic Elements Coordinate Temporal Activity of Key Developmental Gene

In a new study published in Genes & Development, research led by Dr Lila Allou at the MRC Laboratory of Medical Sciences (LMS) in London and Professor Stefan Mundlos at the Max Planck Institute for Molecular Genetics and Charité in Berlin demonstrates how different regulatory genetic elements coordinate the temporal activity of a key developmental gene.

20 Apr 2026

Nonviral Nanoparticles Show Promise for Safer Gene Delivery Methods

In a demonstration that helps pave the way for gene therapies with fewer side effects, several human cell types were genetically modified with protein nanoparticles designed at University of Michigan Engineering and Michigan Medicine.

1 Apr 2026