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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Structure-Guided Protein Engineering Unlocks Safer Methods for Gene Therapy

A joint research team led by Professor Daesik Kim (Department of Medicine, Sungkyunkwan University), along with Professor Yong-Sub Kim (University of Ulsan College of Medicine) and Professor Jae-Hyun Park (Sungkyunkwan University School of Medicine), has announced the development of 'OpenABE' (Open Adenine Base Editor).

31 Jul 2026

Innovative SenMayo Gene Set Consistently Identifies Diverse Senescent Cells

A series of seven Mayo Clinic studies is helping reshape scientists' understanding of senescent, or "zombie," cells - aging cells that no longer divide but remain metabolically active and release inflammatory molecules that contribute to age-related diseases.

31 Jul 2026

Dysfunctional Mitochondria Control Epigenetic Switches to Turn On Inflammatory Genes

Researchers have uncovered a previously unknown mechanism that helps aging cells drive the chronic inflammation linked to many age-related diseases.

31 Jul 2026

New Base Editing Strategy Rewrites Genetic Code to Minimize Huntington's Symptoms

A gene editing tool designed to precisely rewrite the gene that causes Huntington's disease reduced toxic protein fragments and symptoms associated with the disease in mice, researchers at the University of Illinois Urbana-Champaign report.

30 Jul 2026

Northwestern Chemists Repurpose Flexible DNA as Programmable Molecular Glue

For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms.

30 Jul 2026

New Method Enables Faster Oxidation-Free Oligonucleotide Synthesis

Oligonucleotide synthesis is fundamental to genetic analysis, biological research, and nucleic acid therapeutics.

30 Jul 2026

Genetic Breakthrough Allows Early Prediction of Avocado Tree Flower Trait

Scientists have found a genetic switch that could shave years off avocado breeding by allowing researchers to identify one of a young tree's most important traits long before it flowers.

29 Jul 2026

3D Mapping of Tonsil Genetic Structures Unlocks Antibody Optimization

About 2 meters worth of genetic material must fit into the nucleus of each and every one of most of our trillions of cells, coiling and winding to form what looks like a tangled mess.

28 Jul 2026

Molecular Insights Into Fungal Effectors Disabling Host Immune Transcription Factors

Plants defend themselves through a layered innate immune system: pathogen-associated molecular pattern-triggered immunity (PTI) and effector-triggered immunity (ETI), mediated by pattern recognition receptors (PRRs) and nucleotide-binding leucine-rich repeat (NLR) receptors, respectively.

28 Jul 2026

Study Uncovers Two Distinct Embryonic Macrophage Populations with Different Repair Abilities

In leukemia's most aggressive forms, the blood cell factories in our bone marrow falter. Instead of dividing and multiplying at their usual prolific pace, generating hundreds of billions of new cells daily, some precursor cells stall out at an immature stage.

27 Jul 2026

Synthetic Biology Breakthrough Rebuilds Basic Features of Cellular Life

Nature is beautiful, powerful and essential. But nature is not always gentle. The same biological world that gives rise to forests, coral reefs and human life also produces infections, cancer, genetic disease, crop blights and toxins.

24 Jul 2026

Kobe University Unveils Mass-Producible Off-the-Shelf Cancer Fighters

Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted into mice. The Kobe University development is a significant contribution towards faster and cheaper cancer immunotherapy.

24 Jul 2026

Scientists Uncover Unexpected Mechanism Behind Extreme Antibiotic Resistance

A patient with a severe infection is prescribed a potent antibiotic. Hopes for improvement are high, but just after treatment is given, resistance to the drug increases thousands of times. How could this happen?

24 Jul 2026

Scientists Discover Altered 3D Genome Structure in Alzheimer’s Brains

Researchers from Carnegie Mellon University's School of Computer Science, the University of Pittsburgh School of Medicine and the University of Washington shed new light on Alzheimer's disease that could point to new directions for treatment.

24 Jul 2026

Chemotherapy Leaves Distinct DNA Changes in Childhood Tumors

Nearly half of childhood tumors treated with common types of chemotherapy showed detectable DNA changes linked to treatment within 18 months, according to a new international study led by The Hospital for Sick Children (SickKids).

24 Jul 2026

CRISPR Gene Editing Reveals How Enhancer Hierarchies Regulate Gene Expression

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated.

23 Jul 2026

Bacteria Use CRISPR-Cas to Control Diverse Innate Defense Systems

All cellular life-from humans to bacteria-possesses two layers of immunity: innate and adaptive. Scientists have long understood how these two types of immunity work together in higher organisms but not in the microbial world.

23 Jul 2026

New Research Explains How Toxoplasma Parasite Bookmarks Its Genes

A parasite carried by billions of people worldwide often causes harmful infections during pregnancy, in immunocompromised individuals, and is the cause of a leading infectious blindness in South America.

22 Jul 2026

Tough Bacterial Spores Unlock New Bioengineering Frontiers

A remarkable quality of bioengineering is the fact that scientists can take biological processes honed by millions of years of evolution and use them to efficiently create drugs, chemicals, and other products to improve our lives.

21 Jul 2026