Genomic News and Research

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Genetic Prediction Tools May Misjudge Mutation Risks, Study Finds

When a patient has their DNA read, it gets compared against a reference version of the human genome. It allows geneticists and rare disease experts to look at a list of places where the patient's DNA differs.

4 Sep 2026

OGT Expands Sureseq™ Universal NGS Unique Dual Index (UDI) Capabilities to Support Upto 384 Samples Per Sequencing Run

OGT, a leading global provider of genomic research and diagnostic solutions, today announced the expansion of its SureSeq™ Universal NGS Unique Dual Index (UDI) range, enabling laboratories to multiplex up to 384 uniquely indexed samples in a single sequencing run.

4 Sep 2026

Study Reveals Hidden Mutational Process in Colorectal Cancer

The discovery of SBS111 in colorectal cancer offers new perspectives on mutational processes and DNA repair, emphasizing its significance in tumor biology.

3 Sep 2026

Research Sheds Light on Molecular Origins of Pediatric Brain Cancers

Melbourne researchers have uncovered a critical signaling pathway that controls the timing of brain development, shedding new light on how neurodevelopmental disorders may develop.

3 Sep 2026

Bacterial Protein Fragment Disrupts Cell Quality Systems Causing Tissue Scarring

A bacterial protein fragment called corisin drives the process of pulmonary fibrosis by infiltrating and disrupting the cell's quality-control system, researchers at the University of Illinois Urbana-Champaign and Mie University in Japan found in a new study.

1 Sep 2026

Super-Resolution DNA Imaging Platform Links Chromatin Loosening to Tumor Progression

Scientists have engineered fluorescent molecules enabling the visualization of DNA organization within living cells with unparalleled resolution, and in fixed cells, nearly the width of the double helix itself.

31 Aug 2026

Moving Beyond DNA Sequencing Unlocks New Paths Managing Human Health

Scientists from Gladstone Institutes, UC San Francisco, and Stanford University, in collaboration with Biohub, have unveiled a massive, high-resolution functional map of human immune cells that promises to transform our understanding of how genetics control health and disease.

31 Aug 2026

Researchers Struggle Tracking Human Dementia Progress Using Traditional Laboratory Mice

Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional animal models.

31 Aug 2026

Primate-Specific DNA Change Reveals a New Link to Dementia-Related Neurodegeneration

29 Aug 2026

Cellular Glue Helps Engulf Dying Cells

A protein which sticks cells and tissues together has been found to have a surprising second job: helping cells which are packed into a continuous sealed layer, also known as epithelial cells, engulf nearby dead cells.

28 Aug 2026

Bat DNA Offers Insights Into Longevity and Cancer Resistance

Bats are anomalies in the mammalian world-they fly, have long lifespans, and rarely get cancer. Scientists now suspect the bat immune system enables them to live longer without disease, according to a new study published today in Nature.

27 Aug 2026

Researchers Map First Chromosome-Scale Genomes for Sustainable Prairie Crops

The Land Institute and HudsonAlpha Institute for Biotechnology, in collaboration with key partners, have assembled the first chromosome-scale, haplotype-phased genomes for Silphium integrifolium (rosinweed, silflower) and Silphium perfoliatum (cup plant, silphie).

25 Aug 2026

Study Redefines How Cancer Cells Enter Senescence

Stopping tumor growth is only half the battle. Rather than kill tumor cells, many cancer therapies can only push them into cellular senescence, a state in which cells stop dividing but do not die. These "undead" cells will continue to release signals that reshape the tumor environment.

21 Aug 2026

New Potential Target for Triple-Negative Breast Cancer

The study uncovers how macrophages recruit nerves in triple-negative breast cancer, suggesting BDNF signaling as a critical factor in tumor progression.

18 Aug 2026

New Chromosome-Level Pangenome Graph Maps Apricot's Genetic Diversity

Cultivated apricot, Prunus armeniaca, emerged through at least two domestication routes from Central Asia before spreading toward China and the Mediterranean.

17 Aug 2026

Histone Variants Control DNA Methylation Patterns in Plant Genomes

Histone variants help establish DNA methylation at transposons (jumping genes) while preventing this epigenetic modification from spreading to essential genes in plants, reveals a study from Institute of Science Tokyo.

17 Aug 2026

Genomic Database Analysis Identifies New Target for Triple-Negative Breast Tumors

Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence of estrogen receptor, progesterone receptor, and HER2 expression, rendering it insensitive to conventional endocrine and targeted therapies.

13 Aug 2026

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight loss also helps protect the liver from inflammation through a previously unknown signaling pathway, opening new possibilities for treating advanced fatty liver disease.

11 Aug 2026

Bone Marrow T Cells Exhibit Conditional Preparedness Against Cancer

A team led by researchers from the German Cancer Research Center (DKFZ), the HI-STEM Stem Cell Institute, and Medical Clinic V at Heidelberg University Hospital (UKHD) has characterized T cells in the bone marrow in cases of multiple myeloma and acute myeloid leukemia: A specific group of tumor-reactive T cells can recognize and, in principle, fight cancer cells, but is often not sufficiently activated.

10 Aug 2026

Mapping Alternative RNA Splice Isoforms to Identify Novel Therapeutic Targets

Proteogenomics represents a transformative approach in cancer research that bridges the gap between genomic alterations and their functional consequences at the protein level.

8 Aug 2026