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Prehistoric Genome Pushes Back Origins of Treponemal Diseases in the Americas

Scientists have recovered a genome of Treponema pallidum – the bacterium whose subspecies today are responsible for four treponemal diseases, including syphilis – from 5,500-year-old human remains in Sabana de Bogotá, Colombia.

24 Jan 2026

Large African Ancestry Genetic Study Reveals Shared Biology Of Schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

24 Jan 2026

Hidden Sperm RNA Remodeling With Age May Impact Next Generation

Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity and stillbirth. But what drives this increased risk remains unknown.

21 Jan 2026

Yeast-Based Platform Achieves Animal-Free High Quality Chondroitin Sulfate

By systematically redesigning multiple metabolic modules inside Komagataella phaffii, the researchers achieved both high product yield and high sulfation quality, two goals that have long been difficult to reach at the same time.

21 Jan 2026

Replacing Large Mouse Gene Regions with Human DNA

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges.

19 Jan 2026

Unveiling How a Respiratory Bacterium Obtains Lipids and Targets Fatty Tissues

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body.

16 Jan 2026

Giant Virus with A Massive Genome and Unusual Infection Strategy

Ushikuvirus, a newly identified giant virus, showcases unique cytopathic effects and structural features, enhancing knowledge of viral evolution and diversity.

14 Jan 2026

Population-Specific Proteomic Analysis Advances Precision Medicine for Type 2 Diabetes

Researchers have conducted the most comprehensive analysis to date linking plasma proteins to genetic variation in individuals from continental Africa.

9 Jan 2026

Synthetic RNA Platform Converts Viral Replication Into Detectable Cellular Signals

The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication machinery to switch on reporter or therapeutic genes precisely in infected cells.

9 Jan 2026

MD Anderson and SOPHiA GENETICS Partner to Advance AI-Driven Cancer Care

The University of Texas MD Anderson Cancer Center and SOPHiA GENETICS today announced a strategic collaboration that unites SOPHiA GENETICS' AI-powered analytics with MD Anderson's clinical and scientific expertise to accelerate data-driven cancer care through new tools that can accurately analyze, interpret and translate diagnostic results into clinical practice.

8 Jan 2026

High-Tech Imaging Unlocks Genetic Secrets Of Nutrient-Rich Seeds

By rapidly analyzing nearly 12,000 individual seeds, the approach uncovers genetic loci that simultaneously influence seed morphology and mineral composition, opening new avenues for crop biofortification and safer food production.

7 Jan 2026

LINE-1 Retrotransposons Reshape Cancer Genome Architecture

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.

6 Jan 2026

Study Resolves Ancient Genome Duplication History of Flowering Plants

Angiosperms, also known as flowering plants, represent the most diverse group of seed plants, and their origin and evolution have long been a central question in plant evolutionary biology.

5 Jan 2026

Mapping Two Millennia of Betaherpesvirus Evolution via Ancient Human Genomes

Researchers have successfully reconstructed the ancient genomes of Human betaherpesvirus 6A and 6B (HHV-6A/B) from human remains that are over two thousand years old.

5 Jan 2026

Base-Pair Resolution Benchmark Uncovers Structural Variation Complexity in Tomato Genomes

Structural variations (SVs), including insertions, deletions, inversions, and substitutions, can profoundly influence gene regulation and phenotype.

2 Jan 2026

Genomic Test Can Accurately Identify Early Recurrence Risk in Prostate Cancer Patients

A new Moffitt Cancer Center study suggests a widely used genomic test can more accurately identify which men with early prostate cancer are at high risk for their disease to come back quickly after treatment, particularly African American men who face the highest burden from this disease.

26 Dec 2025

Antibiotic Resistance: A Global Crisis Threatening Modern Medicine's Future

Once a medical miracle, antibiotics are now losing their power. Across the world, common infections are becoming harder-and sometimes impossible-to treat. This new review paints a sobering picture of global antimicrobial resistance (AMR), tracing how bacteria and fungi are evolving faster than medicine can respond.

24 Dec 2025